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Autophagy Volume 10, 2014 - Issue 8
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Clinical Research Paper

Combined MTOR and autophagy inhibition

Phase I trial of hydroxychloroquine and temsirolimus in patients with advanced solid tumors and melanoma

Reshma Rangwala Department of Medicine and the Abramson Cancer Center; Perelman School of Medicine; University of Pennsylvania; Philadelphia, PA USA
,
Yunyoung C Chang Department of Medicine and the Abramson Cancer Center; Perelman School of Medicine; University of Pennsylvania; Philadelphia, PA USA
,
Janice Hu Department of Medicine and the Abramson Cancer Center; Perelman School of Medicine; University of Pennsylvania; Philadelphia, PA USA
,
Kenneth M Algazy Department of Medicine and the Abramson Cancer Center; Perelman School of Medicine; University of Pennsylvania; Philadelphia, PA USA
,
Tracey L Evans Department of Medicine and the Abramson Cancer Center; Perelman School of Medicine; University of Pennsylvania; Philadelphia, PA USA
,
Leslie A Fecher Department of Medicine and the Abramson Cancer Center; Perelman School of Medicine; University of Pennsylvania; Philadelphia, PA USA
,
Lynn M Schuchter Department of Medicine and the Abramson Cancer Center; Perelman School of Medicine; University of Pennsylvania; Philadelphia, PA USA
,
Drew A Torigian Department of Radiology Perelman School of Medicine; University of Pennsylvania; Philadelphia, PA USA
,
Jeffrey T Panosian Department of Radiology Perelman School of Medicine; University of Pennsylvania; Philadelphia, PA USA
,
Andrea B Troxel Center for Biostatistics and Epidemiology; University of Pennsylvania; Philadelphia, PA USA
,
Kay-See Tan Center for Biostatistics and Epidemiology; University of Pennsylvania; Philadelphia, PA USA
,
Daniel F Heitjan Center for Biostatistics and Epidemiology; University of Pennsylvania; Philadelphia, PA USA
,
Angela M DeMichele Department of Medicine and the Abramson Cancer Center; Perelman School of Medicine; University of Pennsylvania; Philadelphia, PA USA
,
David J Vaughn Department of Medicine and the Abramson Cancer Center; Perelman School of Medicine; University of Pennsylvania; Philadelphia, PA USA
,
Maryann Redlinger Department of Medicine and the Abramson Cancer Center; Perelman School of Medicine; University of Pennsylvania; Philadelphia, PA USA
,
Abass Alavi Department of Radiology Perelman School of Medicine; University of Pennsylvania; Philadelphia, PA USA
,
Jonathon Kaiser Department of Pharmacy Practice and Pharmacy Administration; Philadelphia College of Pharmacy; University of the Sciences; Philadelphia, PA USA
,
Laura Pontiggia Department of Mathematics, Physics, and Statistics; University of the Sciences; Philadelphia, PA USA
,
Lisa E Davis Department of Medicine and the Abramson Cancer Center; Perelman School of Medicine; University of Pennsylvania; Philadelphia, PA USA; Department of Pharmacy Practice and Pharmacy Administration; Philadelphia College of Pharmacy; University of the Sciences; Philadelphia, PA USA
,
Peter J O’Dwyer Department of Medicine and the Abramson Cancer Center; Perelman School of Medicine; University of Pennsylvania; Philadelphia, PA USA
&
Ravi K Amaravadi Department of Medicine and the Abramson Cancer Center; Perelman School of Medicine; University of Pennsylvania; Philadelphia, PA USACorrespondence[email protected]
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Pages 1391-1402 | Received 21 Nov 2013, Accepted 05 May 2014, Published online: 20 May 2014

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