Inactivation of Brca2 cooperates with Trp53^R172H to induce invasive pancreatic ductal adenocarcinomas in mice

A mouse model of familial pancreatic cancer

Georg Feldmann University of Bonn, Center of Integrated Oncology Cologne-Bonn, Bonn, Germany; Johns Hopkins University, Baltimore, MD USA

Collins Karikari Johns Hopkins University, Baltimore, MD USA

Marco dal Molin Johns Hopkins University, Baltimore, MD USA

Stephanie Duringer Philipps-University Marburg, Germany

Petra Volkmann Philipps-University Marburg, Germany

Detlef K. Bartsch Philipps-University Marburg, Germany

Savita Bisht University of Bonn, Center of Integrated Oncology Cologne-Bonn, Bonn, Germany; Johns Hopkins University, Baltimore, MD USA

Jan-Bart Koorstra Johns Hopkins University, Baltimore, MD USA

Peter Brossart University of Bonn, Center of Integrated Oncology Cologne-Bonn, Bonn, Germany

Anirban Maitra Johns Hopkins University, Baltimore, MD USACorrespondence[email protected] [email protected]