Sustained activation of DNA damage response in irradiated apoptosis-resistant cells induces reversible senescence associated with mTOR downregulation and expression of stem cell markers

Zhanna V Chitikova Institute of Cytology; Russian Academy of Sciences; St. Petersburg, Russia; Saint Petersburg State University; St. Petersburg, Russia

Serguei A Gordeev Institute of Cytology; Russian Academy of Sciences; St. Petersburg, Russia; Saint Petersburg State University; St. Petersburg, Russia

Tatiana V Bykova Institute of Cytology; Russian Academy of Sciences; St. Petersburg, Russia; Saint Petersburg State University; St. Petersburg, Russia

Svetlana G Zubova Institute of Cytology; Russian Academy of Sciences; St. Petersburg, Russia; Saint Petersburg State University; St. Petersburg, Russia

Valery A Pospelov Institute of Cytology; Russian Academy of Sciences; St. Petersburg, Russia; Saint Petersburg State University; St. Petersburg, Russia

Tatiana V Pospelova Institute of Cytology; Russian Academy of Sciences; St. Petersburg, Russia; Saint Petersburg State University; St. Petersburg, RussiaCorrespondence[email protected]

Sustained activation of DNA damage response in irradiated apoptosis-resistant cells induces reversible senescence associated with mTOR downregulation and expression of stem cell markers

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Sustained activation of DNA damage response in irradiated apoptosis-resistant cells induces reversible senescence associated with mTOR downregulation and expression of stem cell markers

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