Niacin improves adiponectin secretion, glucose tolerance and insulin sensitivity in diet-induced obese rats

References

• M.E.Vazquez-VelaN.TorresA.R.TovarWhite adipose tissue as endocrine organ and its role in obesityArch Med Res392008715728
   PubMed Web of Science ®Google Scholar
• M.ChandranS.A.PhillipsT.CiaraldiR.R.HenryAdiponectin: more than just another fat cell hormone?Diabetes Care26200324422450
   PubMed Web of Science ®Google Scholar
• K.OhashiN.OuchiY.MatsuzawaAnti-inflammatory and anti-atherogenic properties of adiponectinBiochimie9410201221372142
   PubMed Web of Science ®Google Scholar
• HanS.H.M.J.QuonJ.A.KimK.K.KohAdiponectin and cardiovascular disease: response to therapeutic interventionsJ Am Coll Cardiol4952007531538
   Web of Science ®Google Scholar
• B.FagerbergD.KellisG.BergstromC.J.BehreAdiponectin in relation to insulin sensitivity and insulin secretion in the development of type 2 diabetes: a prospective study in 64-year-old womenJ Intern Med2692011636643
   Web of Science ®Google Scholar
• ShengT.YangK.Adiponectin and its association with insulin resistance and type 2 diabetesJ Genet Genomics352008321326
   PubMed Web of Science ®Google Scholar
• Y.AritaS.KiharaN.OuchiM.TakahashiK.MaedaJ.Miyagawaet alParadoxical decrease of an adipose-specific protein, adiponectin, in obesityBiochem Biophys Res Commun257119997983
   PubMed Web of Science ®Google Scholar
• C.BambaceM.TelescaE.ZoicoA.SepeD.OliosoA.Rossiet alAdiponectin gene expression and adipocyte diameter: a comparison between epicardial and subcutaneous adipose tissue in menCardiovasc Pathol2052011e1536
   Google Scholar
• ZhuW.ChengK.K.P.M.VanhoutteK.S.LamXuA.Vascular effects of adiponectin: molecular mechanisms and potential therapeutic interventionClin Sci (Lond)1142008361374
   PubMed Web of Science ®Google Scholar
• T.KadowakiT.YamauchiN.KubotaK.HaraK.UekiK.TobeAdiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndromeJ Clin Invest1167200617841792
   PubMed Web of Science ®Google Scholar
• HanS.H.I.SakumaE.K.ShinK.K.KohAnti-atherosclerotic and anti-insulin resistance effects of adiponectin: basic and clinical studiesProg Cardiovasc Dis522009126140
   PubMed Web of Science ®Google Scholar
• D.WandersE.P.PlaisanceR.L.JuddPharmacological effects of lipid-lowering drugs on circulating adipokinesWorld J Diabetes142010116128
   Google Scholar
• M.J.ChapmanJ.S.RedfernM.E.McGovernP.GiralNiacin and fibrates in atherogenic dyslipidemia: pharmacotherapy to reduce cardiovascular riskPharmacol Ther12632010314345
   PubMed Web of Science ®Google Scholar
• SongW.L.G.A.FitzGeraldNiacin, an old drug with a new twistJ Lipid Res5410201325862594
   Web of Science ®Google Scholar
• E.P.PlaisanceM.LukasovaS.OffermannsZhangY.CaoG.R.L.JuddNiacin stimulates adiponectin secretion through the GPR109A receptorAm J Physiol Endocrinol Metab29632009E54958
   Web of Science ®Google Scholar
• J.E.DigbyE.McNeillO.J.DyarV.LamD.R.GreavesR.P.ChoudhuryAnti-inflammatory effects of nicotinic acid in adipocytes demonstrated by suppression of fractalkine, RANTES, and MCP-1 and up-regulation of adiponectinAtherosclerosis209120108995
   Web of Science ®Google Scholar
• A.LinkeA.LinkeM.SonnabendM.FasshauerR.HöllriegelG.Schuleret alEffects of extended-release niacin on lipid profile and adipocyte biology in patients with impaired glucose toleranceAtherosclerosis2052009207213
   PubMed Web of Science ®Google Scholar
• ZhaoS.P.YangJ.LiJ.DongS.Z.WuZ.H.Effect of niacin on LXRalpha and PPARgamma expression and HDL-induced cholesterol efflux in adipocytes of hypercholesterolemic rabbitsInt J Cardiol12422008172178
   Web of Science ®Google Scholar
• O.AstapovaT.LeffAdiponectin and PPARγ: cooperative and interdependent actions of two key regulators of metabolismVitam Horm902012143162
   PubMed Web of Science ®Google Scholar
• S.M.GrundyG.L.VegaM.E.McGovernB.R.TullochD.M.KendallD.Fitz-Patricket alEfficacy, safety, and tolerability of once-daily niacin for the treatment of dyslipidemia associated with type 2 diabetes: results of the assessment of diabetes control and evaluation of the efficacy of niaspan trialArch Intern Med16214200215681576
   PubMedGoogle Scholar
• A.M.PoyntenGanS.K.A.D.KriketosA.O'SullivanJ.J.KellyB.A.Elliset alNicotinic acid-induced insulin resistance is related to increased circulating fatty acids and fat oxidation but not muscle lipid contentMetabolism5262003699704
   PubMed Web of Science ®Google Scholar
• Y.KohH.BidstrupD.L.NicholsNiacin increased glucose, insulin, and C-peptide levels in sedentary non-diabetic postmenopausal womenInt J Womens Health62014913920
   Google Scholar
• J.A.PieperOverview of niacin formulations: differences in pharmacokinetics, efficacy, and safetyAm J Health Syst Pharm602003S914 quiz 25
   PubMed Web of Science ®Google Scholar
• ChenL.W.Y.SoLiS.Y.ChengQ.B.J.BoucherP.S.LeungNiacin-induced hyperglycemia is partially mediated via niacin receptor GPR109a in pancreatic isletsMol Cell Endocrinol40420155666
   Web of Science ®Google Scholar
• Y.W.KimJ.Y.KimS.K.LeeSurgical removal of visceral fat decreases plasma free fatty acid and increases insulin sensitivity on liver and peripheral tissue in monosodium-glutamate (MSG)-obese ratsJ Korean Med Sci141999539545
   PubMed Web of Science ®Google Scholar
• WangW.A.BasingerR.A.NeeseM.ChristiansenM.K.HellersteinEffects of nicotinic acid on fatty acid kinetics, fuel selection, and pathways of glucose production in womenAm J Physiol Endocrinol Metab27912000E509
   Web of Science ®Google Scholar
• M.MasoodiO.KudaM.RossmeislP.FlachsJ.KopeckyLipid signaling in adipose tissue: connecting inflammation and metabolismBiochim Biophys Acta185142015503518
   PubMed Web of Science ®Google Scholar
• M.B.ElamD.B.HunninghakeK.B.DavisR.GargC.JohnsonD.Eganet alEffect of niacin on lipid and lipoprotein levels and glycemic control in patients with diabetes and peripheral arterial disease: the ADMIT study: a randomized trial. Arterial Disease Multiple Intervention TrialJAMA28410200012631270
   PubMed Web of Science ®Google Scholar
• YangS.J.J.M.ChoiL.KimS.E.ParkE.J.RheeW.Y.Leeet alNicotinamide improves glucose metabolism and affects the hepatic NAD-sirtuin pathway in a rodent model of obesity and type 2 diabetesJ Nutr Biochem25120146672
   PubMed Web of Science ®Google Scholar
• R.H.KnoppP.AlagonaM.DavidsonA.C.GoldbergS.D.KafonekM.Kashyapet alEquivalent efficacy of a time-release form of niacin (Niaspan) given once-a-night versus plain niacin in the management of hyperlipidemiaMetabolism479199810971104
   PubMed Web of Science ®Google Scholar
• ChangA.M.M.J.SmithA.T.GaleckiC.J.BloemJ.B.HalterImpaired beta-cell function in human aging: response to nicotinic acid-induced insulin resistanceJ Clin Endocrinol Metab919200633033309
   Web of Science ®Google Scholar
• LiD.TianY.J.GuoJ.SunW.P.Y.Z.LunGuoM.et alNicotinamide supplementation induces detrimental metabolic and epigenetic changes in developing ratsBr J Nutr11012201321562164
   Web of Science ®Google Scholar
• M.BluherAdipose tissue dysfunction in obesityExp Clin Endocrinol Diabetes1172009241250
   PubMed Web of Science ®Google Scholar
• M.BajajR.Medina-NavarroS.SuraamornkulC.MeyerR.A.DeFronzoL.J.MandarinoParadoxical changes in muscle gene expression in insulin-resistant subjects after sustained reduction in plasma free fatty acid concentrationDiabetes5632007743752
   Web of Science ®Google Scholar
• J.A.VitariusThe metabolic syndrome and cardiovascular diseaseMt Sinai J Med722005257262
   Google Scholar
• M.FasshauerJ.KleinS.NeumannM.EszlingerR.PaschkeHormonal regulation of adiponectin gene expression in 3T3- L1 adipocytesBiochem Biophys Res Commun290200210841089
   PubMed Web of Science ®Google Scholar
• A.T.TurerP.E.SchererAdiponectin: mechanistic insights and clinical implicationsDiabetologia55201223192326
   PubMed Web of Science ®Google Scholar