- World Health Organization. Global tuberculosis control 2011. Geneva: WHO Press, 2011. Available at http://www.who.int/entity/tb/publications/global_report/2011/gtbr11_full.pdf. (accessed 1 February 2012).
- Murray M, Oxlade O, Lin HH.Modeling social, environmental and biological determinants of tuberculosis. Int J Tuberc Lung Dis2011;15 Suppl 2:S64–S70.
- Lienhardt C.From exposure to disease: the role of environmental factors in susceptibility to and development of tuberculosis. Epidemiol Rev2001;23:288–301.
- Lawn SD, Churchyard G.Epidemiology of HIV-associated tuberculosis. Curr Opin HIV AIDS2009;4:325–333.
- Raviglione MC, Snider DE Jr, Kochi A.Global epidemiology of tuberculosis. Morbidity and mortality of a worldwide epidemic. JAMA1995;273:220–226.
- Getahun H, Gunneberg C, Granich R, Nunn P.HIV infection-associated tuberculosis: the epidemiology and the response. Clin Infect Dis2010;50 Suppl 3:S201–S207.
- Caminero JA.Multidrug-resistant tuberculosis: epidemiology, risk factors and case finding. Int J Tuberc Lung Dis2010;14:382–390.
- Cox HS, McDermid C, Azevedo V et al.Epidemic levels of drug resistant tuberculosis (MDR and XDR-TB) in a high HIV prevalence setting in Khayelitsha, South Africa. PLoS One2010;5:e13901.
- Calver AD, Falmer AA, Murray M et al.Emergence of increased resistance and extensively drug-resistant tuberculosis despite treatment adherence, South Africa. Emerg Infect Dis2010;16:264–271.
- Zhao M, Li X, Xu P et al.Transmission of MDR and XDR tuberculosis in Shanghai, China. PLoS One2009;4:e4370.
- Nodieva A, Jansone I, Broka L, Pole I, Skenders G, Baumanis V.Recent nosocomial transmission and genotypes of multidrug-resistant Mycobacterium tuberculosis. Int J Tuberc Lung Dis2010;14:427–433.
- The Stop TB Partnership and the World Health Organization. The Global Plan to Stop TB, 2011–2015. Geneva: WHO Press, 2010. Available at http://www.stoptb.org/assets/documents/global/plan/TB_GlobalPlanToStopTB2011-2015.pdf. (accessed 30 January 2012).
- United Nations General Assembly. United Nations Millennium Declaration. 2000. Available at http://www.un.org/millennium/declaration/ares552e.pdf. (accessed 14 April 2012).
- The Stop TB Partnership and the World Health Organization. An International Roadmap for Tuberculosis Research.Geneva: WHO Press, 2011. Available at http://www.stoptb.org/assets/documents/resources/publications/technical/tbresearchroadmap.pdf. (accessed 14 April, 2012).
- The World Health Organization and the Stop TB Partnership. Priorities in operational research to improve tuberculosis care and control.Geneva: WHO Press, 2011. Available at http://www.who.int/tb/features_archive/operational_research_priorities/en/index.html. (accessed 1 February 2012).
- Policy Cures. G-FINDER 2011: neglected disease research and development.Sydney: Policy Cures, 2011. Available at http://policycures.org/publications.html. (accessed 2 March 2012).
- NIAID Tuberculosis Working Group. NIAID Research Agenda: multidrug-resistant and extensively drug-resistant tuberculosis.Bethesda: NIAID, 2007. Available at http://www.niaid.nih.gov/topics/tuberculosis/research/documents/mdrxdrresearchagenda.pdf. (accessed 30 March 2012).
- Bill and Melinda Gates Foundation Global Health Program. Strategy Overview: Tuberculosis. 2009. Available at http://www.gatesfoundation.org/global-health/Documents/tuberculosis-strategy.pdf. (accessed 2 May 2012).
- Brennan MJ, Thole J.Tuberculosis vaccines: a strategic blueprint for the next decade. Tuberculosis2012;92 Suppl 1:S6–S13.
- Daniel TM.The history of tuberculosis. Respir Med2006;100:1862–1870.
- Abu-Raddad LJ, Sabatelli L, Achterberg JT et al.Epidemiological benefits of more-effective tuberculosis vaccines, drugs, and diagnostics. Proc Natl Acad Sci U S A2009;106:13980–13985.
- Lonnroth K, Raviglione M.Global epidemiology of tuberculosis: prospects for control. Semin Respir Crit Care Med2008;29:481–491.
- Russell DG, Barry CE 3rd, Flynn JL.Tuberculosis: what we don't know can, and does, hurt us. Science2010;328:852–856.
- Global Alliance for TB Drug Development.Tuberculosis. Scientific blueprint for tuberculosis drug development. Tuberculosis (Edinb)2001;81 Suppl 1:S1–S52.
- Walker KB, Brennan MJ, Ho MM et al.The second Geneva Consensus: recommendations for novel live TB vaccines. Vaccine2010;28: 2259–2270.
- The New Diagnostics Working Group of the Stop TB Partnership. Pathways to better diagnostics for tuberculosis: a blueprint for the development of TB diagnostics.Geneva: WHO Press, 2009. Available at http://whqlibdoc.who.int/publications/2009/9789241598811_eng.pdf. (accessed 22 January 2012).
- Vynnycky E, Fine PE.The natural history of tuberculosis: the implications of age-dependent risks of disease and the role of reinfection. Epidemiol Infect1997;119:183–201.
- Lawn SD, Wood R, Wilkinson RJ.Changing concepts of ‘latent tuberculosis infection’ in patients living with HIV infection. Clin Dev Immunol2011;2011 pii: 980594.
- Achkar JM, Jenny-Avital ER.Incipient and subclinical tuberculosis: defining early disease states in the context of host immune response. J Infect Dis2011;204 Suppl 4:S1179–S1186.
- Esmail H, Barry CE 3rd, Wilkinson RJ.Understanding latent tuberculosis: the key to improved diagnostic and novel treatment strategies. Drug Discov Today2012;17:514–521.
- Rangaka MX, Wilkinson KA, Glynn JR et al.Predictive value of interferon-gamma release assays for incident active tuberculosis: a systematic review and meta-analysis. Lancet Infect Dis2012;12:45–55.
- Mandalakas AM, Detjen AK, Hesseling AC, Benedetti A, Menzies D.Interferon-gamma release assays and childhood tuberculosis: systematic review and meta-analysis. Int J Tuberc Lung Dis2011;15:1018–1032.
- Diel R, Loddenkemper R, Nienhaus A.Predictive value of interferon-gamma release assays and tuberculin skin testing for predicting progression from latent TB infection to disease state: a meta-analysis. Chest2012 Apr 5; https://doi.org/10.1378/chest.11-3157 doi:10.1378/chest.11-3157.
- Gideon HP, Flynn JL.Latent tuberculosis: what the host ‘sees’? Immunol Res2011;50:202–212.
- Walzl G, Ronacher K, Hanekom W, Scriba TJ, Zumla A.Immunological biomarkers of tuberculosis. Nat Rev Immunol2011;11:343–354.
- Ottenhoff TH, Ellner JJ, Kaufmann SH.Ten challenges for TB biomarkers. Tuberculosis (Edinb)2012;92 Suppl 1:S17–S20.
- Berry MP, Graham CM, McNab FW et al.An interferon-inducible neutrophil-driven blood transcriptional signature in human tuberculosis. Nature2010;466:973–977.
- Menzies D, Al Jahdali H, Al Otaibi B.Recent developments in treatment of latent tuberculosis infection. Indian J Med Res2011;133:257–266.
- Ehlers S.Lazy, dynamic or minimally recrudescent? On the elusive nature and location of the mycobacterium responsible for latent tuberculosis. Infection2009;37:87–95.
- Trunz BB, Fine P, Dye C.Effect of BCG vaccination on childhood tuberculous meningitis and miliary tuberculosis worldwide: a meta-analysis and assessment of cost-effectiveness. Lancet2006;367:1173–1180.
- Randhawa AK, Shey MS, Keyser A et al.Association of human TLR1 and TLR6 deficiency with altered immune responses to BCG vaccination in South African infants. PLoS Pathog2011;7:e1002174.
- Ritz N, Hanekom WA, Robins-Browne R, Britton WJ, Curtis N.Influence of BCG vaccine strain on the immune response and protection against tuberculosis. FEMS Microbiol Rev2008;32:821–841.
- Brennan MJ, Clagett B, Fitzgerald H et al.Preclinical evidence for implementing a prime-boost vaccine strategy for tuberculosis. Vaccine2012;30:2811–2823.
- Critical path to TB drug regimens.2012.Available at http://cptrinitiative.org/ (accessed 1 June 2012).
- Blumberg HM, Burman WJ, Chaisson RE et al.American Thoracic Society/Centers for Disease Control and Prevention/Infectious Diseases Society of America: treatment of tuberculosis. Am J Respir Crit Care Med2003;167:603–662.
- World Health Organization. Guidelines for programmatic management of drug-resistant tuberculosis.Geneva: WHO Press, 2011. Available at http://whqlibdoc.who.int/publications/2011/9789241501583_eng.pdf. (accessed 14 February 2012).
- Shah NS, Wright A, Bai GH et al.Worldwide emergence of extensively drug-resistant tuberculosis. Emerging infectious diseases2007;13:380–387.
- McDermott W.Microbial persistence. Yale J Biol Med1958;30:257–291.
- Fauvart M, de Groote VN, Michiels J.Role of persister cells in chronic infections: clinical relevance and perspectives on anti-persister therapies. J Med Microbiol2011;60(Pt 6): 699–709.
- Zhang Y, Yew WW, Barer MR.Targeting persisters for tuberculosis control. Antimicrob Agents Chemother2012;56:2223–2230.
- Mitchison DA.The search for new sterilizing anti-tuberculosis drugs. Front Biosci2004;9:1059–1072.
- Yasinskaya Y, Sacks L.Models and approaches for anti-TB drug testing. Expert Rev Anti Infect Ther2011;9:823–831.
- Ma Z, Lienhardt C, McIlleron H, Nunn AJ, Wang X.Global tuberculosis drug development pipeline: the need and the reality. Lancet2010;375:2100–2109.
- Miyata T, Cheigh CI, Casali N et al.An adjunctive therapeutic vaccine against reactivation and post-treatment relapse tuberculosis. Vaccine2012;30:459–465.
- Van Deun A, Salim MA, Das AP, Bastian I, Portaels F.Results of a standardised regimen for multidrug-resistant tuberculosis in Bangladesh. Int J Tuberc Lung Dis2004;8:560–567.
- National Institute of Allergy and Infectious Diseases. Restructuring the NIAID Clinical Trials Networks.Bethesda: National Institute of Allergy and Infectious Diseases; 2012. Available at http://www.niaid.nih.gov/labsandresources/restructuring (accessed 14 February 2012).
- National Institute of Allergy and Infectious Diseases. Resources for researchers.Bethesda: National Institute of Allergy and Infectious Diseases; 2012. Available at http://www.niaid.nih.gov/labsandresources/resources (accessed 1 June 2012).
- Nuermberger EL, Yoshimatsu T, Tyagi S, Bishai WR, Grosset JH.Paucibacillary tuberculosis in mice after prior aerosol immunization with Mycobacterium bovis BCG. Infect Immun2004;72:1065–1071.
- McCune RM, Feldmann FM, Lambert HP, McDermott W.Microbial persistence. I. The capacity of tubercle bacilli to survive sterilization in mouse tissues. J Exp Med1966;123:445–468.
- McCune RM, Feldmann FM, McDermott W.Microbial persistence. II. Characteristics of the sterile state of tubercle bacilli. J Exp Med1966;123:469–486.
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The role of biomedical research in global tuberculosis control: gaps and challenges
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Amanda C Schleif1 National Institute of Allergy and Infectious Diseases, 6610 Rockledge Drive, Bethesda, MD20892, USACorrespondence[email protected]
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Pages 1-6
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Received 02 May 2012, Accepted 23 Jun 2012, Published online: 25 Jan 2019
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