Advanced search
Publication Cover
Emerging Microbes & Infections Volume 3, 2014 - Issue 1
Submit an article Journal homepage
2,123
Views
95
CrossRef citations to date
0
Altmetric
Original Articles

Pathobiological features of a novel, highly pathogenic avian influenza A(H5N8) virus

Young-Il KimCollege of Medicine and Medical Research Institute, Chungbuk National University, Cheongju 361-763, Korea
,
Philippe Noriel Q PascuaCollege of Medicine and Medical Research Institute, Chungbuk National University, Cheongju 361-763, Korea
,
Hyeok-Il KwonCollege of Medicine and Medical Research Institute, Chungbuk National University, Cheongju 361-763, Korea
,
Gyo-Jin LimCollege of Medicine and Medical Research Institute, Chungbuk National University, Cheongju 361-763, Korea
,
Eun-Ha KimCollege of Medicine and Medical Research Institute, Chungbuk National University, Cheongju 361-763, Korea
,
Sun-Woo YoonViral Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305-806, Korea
,
Su-Jin ParkCollege of Medicine and Medical Research Institute, Chungbuk National University, Cheongju 361-763, Korea
,
Se Mi KimCollege of Medicine and Medical Research Institute, Chungbuk National University, Cheongju 361-763, Korea
,
Eun-Ji ChoiCollege of Medicine and Medical Research Institute, Chungbuk National University, Cheongju 361-763, Korea
,
Young-Jae SiCollege of Medicine and Medical Research Institute, Chungbuk National University, Cheongju 361-763, Korea
,
Ok-Jun LeeCollege of Medicine and Medical Research Institute, Chungbuk National University, Cheongju 361-763, Korea
,
Woo-Sub ShimCollege of Medicine and Medical Research Institute, Chungbuk National University, Cheongju 361-763, Korea
,
Si-Wook KimCollege of Medicine and Medical Research Institute, Chungbuk National University, Cheongju 361-763, Korea
,
In-Pil MoCollege of Veterinary Medicine, Chungbuk National University, Cheongju 361-763, Korea
,
Yeonji BaeCollege of Veterinary Medicine, Chungbuk National University, Cheongju 361-763, Korea
,
Yong Taik LimSKKU Advanced Institute of Technology and Department of Chemical Engineering, Sungkyunkwan University, Suwon 440-746, Korea
,
Moon Hee SungDepartment of Advanced Fermentation Fusion Science & Technology, Kookmin University, Seoul 136-702, Korea; BioLeaders Corporation, Yongsandong, Yuseong-gu, Daejeon 305-500, Korea
,
Chul-Joong KimCollege of Veterinary Medicine, Chungnam National University, Daejeon 305-764, Korea
,
Richard J WebbyDepartment of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105-3678, USA
,
Robert G WebsterDepartment of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN 38105-3678, USA
&
Young Ki ChoiCollege of Medicine and Medical Research Institute, Chungbuk National University, Cheongju 361-763, KoreaCorrespondence[email protected]
 show all
Pages 1-13 | Received 23 Sep 2015, Accepted 02 Nov 2015, Published online: 25 Jan 2019

  • Eagles D, Siregar ES, Dung DH, Weaver J, Wong F, Daniels P.H5N1 highly pathogenic avian influenza in Southeast Asia. Rev Sci Tech2009;28: 341–348.
  • World Health Organization/Global Influenza Programme. Cumulative number of confirmed human cases for avian influenza A(H5N1) reported to WHO, 2003–2014.Geneva: WHO, 2014.Available at http://www.who.int/influenza/human_animal_interface/EN_GIP_20140124CumulativeNumberH5N1cases.pdf?ua=1 (accessed 24 January 2014).
  • Chen H, Smith GJ, Li KS et al.Establishment of multiple sublineages of H5N1 influenza virus in Asia: implications for pandemic control. Proc Natl Acad Sci USA2006;103: 2845–2450.
  • Gu M, Liu W, Cao Y et al.Novel reassortant highly pathogenic avian influenza (H5N5) viruses in domestic ducks, China. Emerg Infect Dis2011;17: 1060–1063.
  • Gu M, Huang J, Chen Y et al.Genome sequence of a natural reassortant H5N2 avian influenza virus from domestic mallard ducks in eastern China. J Virol2012;86: 12463–12464.
  • Guan Y, Peiris JS, Lipatov AS et al.Emergence of multiple genotypes of H5N1 avian influenza viruses in Hong Kong SAR. Proc Natl Acad Sci USA2002;99: 8950–5955.
  • Zhao G, Gu X, Lu X et al.Novel reassortant highly pathogenic H5N2 avian influenza viruses in poultry in China. PLoS One2012;7: e46183.
  • Zhao K, Gu M, Zhong L et al.Characterization of three H5N5 and one H5N8 highly pathogenic avian influenza viruses in China. Vet Microbiol2013;163: 351–357.
  • Zou W, Guo X, Li S, Yang Y, Jin M.Complete genome sequence of a novel natural recombinant H5N5 influenza virus from ducks in central China. J Virol2012;86: 13878.
  • Kwon YK, Joh SJ, Kim MC et al.Highly pathogenic avian influenza (H5N1) in the commercial domestic ducks of South Korea. Avian Pathol2005;34: 367–370.
  • Lee YJ, Choi YK, Kim YJ et al.Highly pathogenic avian influenza virus (H5N1) in domestic poultry and relationship with migratory birds, South Korea. Emerg Infect Dis2008;14: 487–490.
  • Kim HR, Park CK, Lee YJ et al.An outbreak of highly pathogenic H5N1 avian influenza in Korea, 2008. Vet Microbiol2010;141: 362–366.
  • Kim HR, Lee YJ, Park CK et al.Highly pathogenic avian influenza (H5N1) outbreaks in wild birds and poultry, South Korea. Emerg Infect Dis2012;18: 480–483.
  • World Organization for Animal Health/World Animal Health Information Database. WAHID weekly disease information. Vol. 20, No. 04, 17 January 2014.Paris: OIE, 2012.Available at http://www.oie.int/wahis_2/public/wahid.php/Diseaseinformation/WI (accessed 4 June 2014).
  • Lee YJ, Kang HM, Lee EK et al.Novel reassortant influenza A(H5N8) viruses, South Korea, 2014. Emerg Infect Dis2014;20: 1087–1089.
  • Pascua PN, Song MS, Lee JH et al.Virulence and transmissibility of H1N2 influenza virus in ferrets imply the continuing threat of triple-reassortant swine viruses. Proc Natl Acad Sci USA2012;109: 15900–15905.
  • Lukert PD.Immunofluorescence of avian infectious bronchitis virus in primary chicken embryo kidney, liver, lung, and fibroblast cell cultures. Arch Gesamte Virusforsch1966;19: 265–272.
  • Reed LJ, Muench H.A simple method of estimating fifty percent endpoints. Am J Hyg1938;27: 493–497.
  • Pascua PN, Lim GJ, Kwon HI et al.Emergence of H3N2pM-like and novel reassortant H3N1 swine viruses possessing segments derived from the A (H1N1) pdm09 influenza virus, Korea. Influenza Other Respir Viruses2013;7: 1283–1291.
  • Aiyar A.The use of CLUSTAL W and CLUSTAL X for multiple sequence alignment. Methods Mol Biol2000;132: 221–241.
  • Perriere G, Gouy M.WWW-query: an on-line retrieval system for biological sequence banks. Biochimie1996;78: 364–369.
  • Matrosovich MN, Gambaryan AS.Solid-phase assays of receptor-binding specificity. Methods Mol Biol2012;865: 71–94.
  • Paulson JC, Rogers GN.Resialylated erythrocytes for assessment of the specificity of sialyloligosaccharide binding proteins. Methods Enzymol1987;138: 162–168.
  • Itoh Y, Shinya K, Kiso M et al.In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses. Nature2009;460: 1021–1025.
  • Munster VJ, de Wit E, van den Brand JM et al.Pathogenesis and transmission of swine-origin 2009 A(H1N1) influenza virus in ferrets. Science2009;325: 481–483.
  • Zhang Q, Shi J, Deng G et al.H7N9 influenza viruses are transmissible in ferrets by respiratory droplet. Science2013;341: 410–414.
  • Watanabe T, Kiso M, Fukuyama S et al.Characterization of H7N9 influenza A viruses isolated from humans. Nature2013;501: 551–555.
  • Liu J, Xiao H, Lei F et al.Highly pathogenic H5N1 influenza virus infection in migratory birds. Science2005;309: 1206.
  • Gu M, Zhao G, Zhao K et al.Novel variants of clade 2.3.4 highly pathogenic avian influenza A(H5N1) viruses, China. Emerg Infect Dis2013;19: 2021–2024.
  • Zhao Q, Li Q, Zhong L et al.Complete genomic sequence of a novel reassortant H4N2 avian influenza virus isolated from domestic ducks in Jiangsu, China. Genome Announc2013;1: e0009113.
  • Chen H, Yuan H, Gao R et al.Clinical and epidemiological characteristics of a fatal case of avian influenza A H10N8 virus infection: a descriptive study. Lancet2014;383: 714–721.
  • Gao R, Cao B, Hu Y et al.Human infection with a novel avian-origin influenza A (H7N9) virus. N Engl J Med2013;368: 1888–1897.
  • Stevens J, Blixt O, Tumpey TM, Taubenberger JK, Paulson JC, Wilson IA.Structure and receptor specificity of the hemagglutinin from an H5N1 influenza virus. Science2006;312: 404–410.
  • Imai M, Watanabe T, Hatta M et al.Experimental adaptation of an influenza H5 HA confers respiratory droplet transmission to a reassortant H5 HA/H1N1 virus in ferrets. Nature2012;486: 420–428.
  • Linster M, van Boheemen S, de Graaf M et al.Identification, characterization, and natural selection of mutations driving airborne transmission of A/H5N1 virus. Cell2014;157: 329–339.
  • Conenello GM, Zamarin D, Perrone LA, Tumpey T, Palese P.A single mutation in the PB1-F2 of H5N1 (HK/97) and 1918 influenza A viruses contributes to increased virulence. PLoS Pathog2007;3: 1414–1421.
  • McAuley JL, Hornung F, Boyd KL et al.Expression of the 1918 influenza A virus PB1-F2 enhances the pathogenesis of viral and secondary bacterial pneumonia. Cell Host Microbe2007;2: 240–249.
  • Medina RA, Garcia-Sastre A.Influenza A viruses: new research developments. Nat Rev Microbiol2011;9: 590–603.
  • Mehle A, Doudna JA.Adaptive strategies of the influenza virus polymerase for replication in humans. Proc Natl Acad Sci USA2009;106: 21312–21316.
  • Jiao P, Tian G, Li Y et al.A single-amino-acid substitution in the NS1 protein changes the pathogenicity of H5N1 avian influenza viruses in mice. J Virol2008;82: 1146–1154.
  • Intharathep P, Laohpongspaisan C, Rungrotmongkol T et al.How amantadine and rimantadine inhibit proton transport in the M2 protein channel. J Mol Graph Model2008;27: 342–348.
  • Orozovic G, Orozovic K, Lennerstrand J, Olsen B.Detection of resistance mutations to antivirals oseltamivir and zanamivir in avian influenza A viruses isolated from wild birds. PLoS One2011;6: e16028.
  • Eisen MB, Sabesan S, Skehel JJ, Wiley DC.Binding of the influenza A virus to cell-surface receptors: structures of five hemagglutinin–sialyloligosaccharide complexes determined by X-ray crystallography. Virology1997;232: 19–31.
  • Suarez DL, Perdue ML, Cox N et al.Comparisons of highly virulent H5N1 influenza A viruses isolated from humans and chickens from Hong Kong. J Virol1998;72: 6678–6688.
  • Herfst S, Schrauwen EJ, Linster M et al.Airborne transmission of influenza A/H5N1 virus between ferrets. Science2012;336: 1534–1541.
  • World Organization for Animal Health/World Animal Health Information Database. WAHID weekly disease information. Vol. 27, No. 16, 13 April 2014.Paris: OIE, 2012.Available at http://www.oie.int/wahis_2/public/wahid.php/Diseaseinformation/WI (accessed 4 June 2014).
  • Peiris JS, de Jong MD, Guan Y.Avian influenza virus (H5N1): a threat to human health. Clin Microbiol Rev2007;20: 243–267.
  • Sonnberg S, Webby RJ, Webster RG.Natural history of highly pathogenic avian influenza H5N1. Virus Res2013;178: 63–77.
  • Wu H, Peng X, Xu L et al.Novel reassortant influenza A(H5N8) viruses in domestic ducks, eastern China. Emerg Infect Dis2014;20: 1315–1318.
  • Melen K, Kinnunen L, Fagerlund R et al.Nuclear and nucleolar targeting of influenza A virus NS1 protein: striking differences between different virus subtypes. J Virol2007;81: 5995–6006.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.