- KimJ,SudberyP.Candida albicans, a major human fungal pathogen.J Microbiol2011; 49:171–177.
- OddsFC,BrownAJ,GowNA.Antifungal agents: mechanisms of action.Trends Microbiol2003; 11:272–279.
- WarrilowAG,MartelCM,ParkerJEet al.Azole binding properties of Candida albicans sterol 14-alpha demethylase (CaCYP51).Antimicrob Agents Chemother2010; 54:4235–4245.
- SucherAJ,ChahineEB,BalcerHE.Echinocandins: the newest class of antifungals.Ann Pharmacother2009; 43:1647–1657.
- EllisD.Amphotericin B: spectrum and resistance.J Antimicrob Chemother2002; 49:7–10.
- GhannoumMA,RiceLB.Antifungal agents: mode of action, mechanisms of resistance, and correlation of these mechanisms with bacterial resistance.Clin Microbiol Rev1999; 12:501–517.
- AkinsRA.An update on antifungal targets and mechanisms of resistance in Candida albicans.Med Mycol2005; 43:285–318.
- MartinsCV,da SilvaDL,NeresATet al.Curcumin as a promising antifungal of clinical interest.J Antimicrob Chemother2009; 63:337–339.
- SasakiK,AbeH,YoshizakiF.In vitro antifungal activity of naphthoquinone derivatives.Biol Pharm Bull2002; 25:669–670.
- LeeMJ,KaoSH,HunagJEet al.Shikonin time-dependently induced necrosis or apoptosis in gastric cancer cells via generation of reactive oxygen species.Chem Biol Interact2014; 211:44–53.
- NamKN,SonMS,ParkJHet al.Shikonins attenuate microglial inflammatory responses by inhibition of ERK, Akt, and NF-kappaB: neuroprotective implications.Neuropharmacology2008; 55:819–825.
- MiaoH,ZhaoL,LiCet al.Inhibitory effect of Shikonin on Candida albicans growth.Biol Pharm Bull2012; 35:1956–1963.
- UllmannBD,MyersH,ChiranandWet al.Inducible defense mechanism against nitric oxide in Candida albicans.Eukaryot Cell2004; 3:715–723.
- ZemkeAC,ShivaS,BurnsJLet al.Nitrite modulates bacterial antibiotic susceptibility and biofilm formation in association with airway epithelial cells.Free Radic Biol Med2014; 77:307–316.
- FriedmanAJ,BlecherK,SchairerDet al.Improved antimicrobial efficacy with nitric oxide releasing nanoparticle generated S-nitrosoglutathione.Nitric Oxide2011; 25:381–386.
- HaqueSS.Impact of nitric oxide precursor L-arginine on oxidative stress against typhoid.Bratisl Lek Listy2012; 113:589–591.
- LeitchGJ,HeQ.Arginine-derived nitric oxide reduces fecal oocyst shedding in nude mice infected with Cryptosporidium parvum.Infect Immun1994; 62:5173–5176.
- HeilmanBJ,TadleAC,PimentelLRet al.Selective damage to hyphal form through light-induced delivery of nitric oxide to Candida albicans colonies.J Inorg Biochem2013; 123:18–22.
- HromatkaBS,NobleSM,JohnsonAD.Transcriptional response of Candida albicans to nitric oxide and the role of the YHB1 gene in nitrosative stress and virulence.Mol Biol Cell2005; 16:4814–4826.
- ChiranandW,McLeodI,ZhouHet al.CTA4 transcription factor mediates induction of nitrosative stress response in Candida albicans.Eukaryot Cell2008; 7:268–278.
- FonziWA,IrwinMY.Isogenic strain construction and gene mapping in Candida albicans.Genetics1993; 134:717–728.
- NobleSM,FrenchS,KohnLAet al.Systematic screens of a Candida albicans homozygous deletion library decouple morphogenetic switching and pathogenicity.Nat Genet2010; 42:590–598.
- CostaAC,de Campos RasteiroVM,PereiraCAet al.Susceptibility of Candida albicans and Candida dubliniensis to erythrosine- and LED-mediated photodynamic therapy.Arch Oral Biol2011; 56:1299–1305.
- CaoY,ZhuZ,ChenXet al.Effect of amphotericin B on the metabolic profiles of Candida albicans.J Proteome Res2013; 12:2921–2932.
- KaganS,JabbourA,SionovEet al.Anti-Candida albicans biofilm effect of novel heterocyclic compounds.J Antimicrob Chemother2014; 69:416–427.
- VincentBM,LancasterAK,Scherz-ShouvalRet al.Fitness trade-offs restrict the evolution of resistance to amphotericin B.PLoS Biol2013; 11:e1001692.
- FangFC.Antimicrobial reactive oxygen and nitrogen species: concepts and controversies.Nat Rev Microbiol2004; 2:820–832.
- MacherlaC,SanchezDA,AhmadiMSet al.Nitric oxide releasing nanoparticles for treatment of Candida albicans burn infections.Front Microbiol2012; 3:193.
- AranaDM,NombelaC,PlaJ.Fluconazole at subinhibitory concentrations induces the oxidative- and nitrosative-responsive genes TRR1, GRE2 and YHB1, and enhances the resistance of Candida albicans to phagocytes.J Antimicrob Chemother2010; 65:54–62.
- TillmannA,GowNA,BrownAJ.Nitric oxide and nitrosative stress tolerance in yeast.Biochem Soc Trans2011; 39:219–223.
- HelmickRA,FletcherAE,GardnerAMet al.Imidazole antibiotics inhibit the nitric oxide dioxygenase function of microbial flavohemoglobin.Antimicrob Agents Chemother2005; 49:1837–1843.
- SellamA,TebbjiF,WhitewayMet al.A novel role for the transcription factor Cwt1p as a negative regulator of nitrosative stress in Candida albicans.PLoS One2012; 7:e43956.
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Original Articles
Endogenous nitric oxide accumulation is involved in the antifungal activity of Shikonin against Candida albicans
Zebin LiaoSchool of Pharmacy, Second Military Medical University, Shanghai200433, China
, Yu YanSchool of Pharmacy, Second Military Medical University, Shanghai200433, China
, Huaihuai DongSchool of Pharmacy, Second Military Medical University, Shanghai200433, China
, Zhenyu ZhuSchool of Pharmacy, Second Military Medical University, Shanghai200433, China
, Yuanying JiangSchool of Pharmacy, Second Military Medical University, Shanghai200433, ChinaCorrespondence[email protected] [email protected]
& Yingying CaoSchool of Pharmacy, Second Military Medical University, Shanghai200433, ChinaCorrespondence[email protected] [email protected]
Pages 1-6
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Received 26 Aug 2015, Accepted 22 Mar 2016, Published online: 25 Jan 2019
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