1,398
Views
7
CrossRef citations to date
0
Altmetric
Original Articles

A multi-omic analysis reveals the regulatory role of CD180 during the response of macrophages to Borrelia burgdorferi

, , , , , , ORCID Icon, , , , , , , , , , ORCID Icon, & ORCID Icon show all
Pages 1-13 | Received 11 Sep 2017, Accepted 14 Dec 2017, Published online: 07 Mar 2018

References

  • NaglMPhagocytosis and killing of bacteria by professional phagocytes and dendritic cellsClin. Diagn. Lab. Immunol.20029 1165 1168130096
  • AderemAPhagocytosis and the inflammatory responseJ. Infect. Dis.2003187Suppl 2S340S34510.1086/374747
  • MorettiJBlanderJMInsights into phagocytosis-coupled activation of pattern recognition receptors and inflammasomesCurr. Opin. Immunol.20142610011010.1016/j.coi.2013.11.003
  • RizzoliALyme borreliosis in EuropeEur. Surveill.20111619906
  • Olson, C. J., Fikrig, E., Anguita, J. in Clinical Immunology 4th edn (eds Rich, R.R., Fleisher, T.A., Schoroeder, H.W., Weyand, C.M. & Frew, A.J.) (Elsevier, Philadelphia, PA, 2013).
  • SchotthoeferAMFrostHMEcology and epidemiology of lyme borreliosisClin. Lab. Med.20153572374310.1016/j.cll.2015.08.003
  • KuehnBMCDC estimates 300,000 US cases of lyme disease annuallyJAMA2013310111010.1001/jama.2013.278331
  • MurrayTSShapiroEDLyme diseaseClin. Lab. Med.20103031132810.1016/j.cll.2010.01.0033652387
  • ChomelBLyme diseaseRev. Sci. Technol.20153456957610.20506/rst.34.2.2380
  • LelovasPDontasIBassiakouEXanthosTCardiac implications of Lyme disease, diagnosis and therapeutic approachInt. J. Cardiol.2008129152110.1016/j.ijcard.2008.01.044
  • AucottJNSeifterARebmanAWProbable late lyme disease: a variant manifestation of untreated Borrelia burgdorferi infectionBMC Infect. Dis.20121210.1186/1471-2334-12-1733449205
  • CervantesJLPhagosomal TLR signaling upon Borrelia burgdorferi infectionFront Cell Infect. Microbiol.20144554033037
  • HawleyKLCD14 cooperates with complement receptor 3 to mediate MyD88-independent phagocytosis of Borrelia burgdorferiProc. Natl Acad. Sci. USA20121091228123210.1073/pnas.11120781093268315
  • Petnicki-OcwiejaTTRIF mediates Toll-like receptor 2-dependent inflammatory responses to Borrelia burgdorferiInfect. Immun.20138140241010.1128/IAI.00890-123553797
  • HoviusJWThe urokinase receptor (uPAR) facilitates clearance of Borrelia burgdorferiPLoS Pathog.20095e100044710.1371/journal.ppat.10004472678258
  • OlsonCLocal production of IFN-gamma by invariant NKT cells modulates acute lyme carditisJ. Immunol.20091823728373410.4049/jimmunol.08041112679988
  • HawleyKMacrophage p38 mitogen-activated protein kinase activity regulates invariant natural killer T-cell responses during Borrelia burgdorferi infectionJ. Infect. Dis.201220628329110.1093/infdis/jis3323490691
  • CervantesJLPhagosomal signaling by Borrelia burgdorferi in human monocytes involves toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-{beta}Proc. Natl Acad. Sci. USA20111083683368810.1073/pnas.10137761083048123
  • PetzkeMMBrooksAKrupnaMAMordueDSchwartzIRecognition of Borrelia burgdorferi, the lyme disease spirochete, by TLR7 and TLR9 induces a type I IFN response by human immune cellsJ. Immunol.20091835279529210.4049/jimmunol.0901390
  • SalazarJCActivation of human monocytes by live Borrelia burgdorferi generates TLR2-dependent and -independent responses which include induction of IFN-betaPLoS Pathog.20095e100044410.1371/journal.ppat.10004442679197
  • CruzARPhagocytosis of Borrelia burgdorferi, the Lyme disease spirochete, potentiates innate immune activation and induces apoptosis in human monocytesInfect. Immun.200876567010.1128/IAI.01039-07
  • BadawiAThe potential of omics technologies in lyme disease biomarker discovery and early detectionInfect. Dis. Ther.201768510210.1007/s40121-016-0138-6
  • Dunham-EmsSMLive imaging reveals a biphasic mode of dissemination of Borrelia burgdorferi within ticksJ. Clin. Invest.20091193652366510.1172/JCI394012786795
  • Garcia-CaoISystemic elevation of PTEN induces a tumor-suppressive metabolic stateCell2012149496210.1016/j.cell.2012.02.0303319228
  • TrapnellCPachterLSalzbergSLTopHat: discovering splice junctions with RNA-SeqBioinformatics2009251105111110.1093/bioinformatics/btp1202672628
  • LoveMIHuberWAndersSModerated estimation of fold change and dispersion for RNA-seq data with DESeq2Genome Biol.20141510.1186/s13059-014-0550-84302049
  • DuPKibbeWALinSMlumi: a pipeline for processing Illumina microarrayBioinformatics2008241547154810.1093/bioinformatics/btn224
  • RitchieMElimma powers differential expression analyses for RNA-sequencing and microarray studiesNucleic Acids Res.201543e4710.1093/nar/gkv0074402510
  • YuGWangLGHanYHeQYclusterProfiler: an R package for comparing biological themes among gene clustersOMICS20121628428710.1089/omi.2011.01183339379
  • ThomasPDPANTHER: a library of protein families and subfamilies indexed by functionGenome Res.2003132129214110.1101/gr.772403403709
  • AshburnerMGene ontology: tool for the unification of biology. The Gene Ontology ConsortiumNat. Genet.200025252910.1038/755563037419
  • KanehisaMGotoSKawashimaSNakayaAThe KEGG databases at GenomeNetNucleic Acids Res.200230424610.1093/nar/30.1.4299091
  • WisniewskiJRZougmanANagarajNMannMUniversal sample preparation method for proteome analysisNat. Methods2009635936210.1038/nmeth.1322
  • HensonPSuppression of macrophage inflammatory responses by PPARsProc. Natl Acad. Sci. USA20031006295629610.1073/pnas.1232410100164439
  • RicoteMHuangJTWelchJSGlassCKThe peroxisome proliferator-activated receptor (PPARgamma) as a regulator of monocyte/macrophage functionJ. Leukoc. Biol.19996673373910.1002/jlb.66.5.733
  • JiangCTingATSeedBPPAR-gamma agonists inhibit production of monocyte inflammatory cytokinesNature1998391828610.1038/34184
  • GinhouxFJungSMonocytes and macrophages: developmental pathways and tissue homeostasisNat. Rev. Immunol.20141439240410.1038/nri3671
  • PatinECOrrSJSchaibleUEMacrophage inducible C-type lectin as a multifunctional player in immunityFront. Immunol.2017886110.3389/fimmu.2017.008615525440
  • ShinOSDistinct roles for MyD88 and Toll-like receptors 2, 5, and 9 in phagocytosis of Borrelia burgdorferi and cytokine inductionInfect. Immun.2008762341235110.1128/IAI.01600-072423091
  • YuCHRP105 engages phosphatidylinositol 3-kinase p110delta to facilitate the trafficking and secretion of cytokines in macrophages during mycobacterial infectionJ. Immunol.20151953890390010.4049/jimmunol.1500017
  • LiuBRP105 involved in activation of mouse macrophages via TLR2 and TLR4 signalingMol. Cell Biochem.201337818319310.1007/s11010-013-1609-7
  • WheelockCEApplication of ‘omics technologies to biomarker discovery in inflammatory lung diseasesEur. Respir. J.20134280282510.1183/09031936.00078812
  • Abu-AsabMSBiomarkers in the age of omics: time for a systems biology approachOMICS20111510511210.1089/omi.2010.00233060038
  • BouquetJLongitudinal transcriptome analysis reveals a sustained differential gene expression signature in patients treated for acute Lyme diseasemBio20167e00100e0011610.1128/mBio.00100-164791844
  • MolinsCRDevelopment of a metabolic biosignature for detection of early Lyme diseaseClin. Infect. Dis.2015601767177510.1093/cid/civ1854810808
  • SoloskiMJSerum inflammatory mediators as markers of human Lyme disease activityPLoS ONE20149e9324310.1371/journal.pone.00932433989169
  • GautamAInterleukin-10 alters effector functions of multiple genes induced by Borrelia burgdorferi in macrophages to regulate Lyme disease inflammationInfect. Immun.2011794876489210.1128/IAI.05451-113232652
  • SteevelsTAMeyaardLImmune inhibitory receptors: essential regulators of phagocyte functionEur. J. Immunol.20114157558710.1002/eji.201041179
  • BerendeAOostingMKullbergBJNeteaMGJoostenLAActivation of innate host defense mechanisms by BorreliaEur. Cytokine Netw.201021718
  • ColemanJLBenachJLThe urokinase receptor can be induced by Borrelia burgdorferi through receptors of the innate immune systemInfect. Immun.2003715556556410.1128/IAI.71.10.5556-5564.2003201106
  • OostingMRecognition of Borrelia burgdorferi by NOD2 is central for the induction of an inflammatory reactionJ. Infect. Dis.20102011849185810.1086/652871
  • RadolfJDTreponema pallidum and Borrelia burgdorferi lipoproteins and synthetic lipopeptides activate monocytes/macrophagesJ. Immunol.199515428662877
  • BrownJPZacharyJFTeuscherCWeisJJWootenRMDual role of interleukin-10 in murine Lyme disease: regulation of arthritis severity and host defenseInfect. Immun.1999675142515096863
  • ChungYZhangNWootenRMBorrelia burgdorferi elicited-IL-10 suppresses the production of inflammatory mediators, phagocytosis, and expression of co-stimulatory receptors by murine macrophages and/or dendritic cellsPLoS ONE20138e8498010.1371/journal.pone.00849803868605
  • GiambartolomeiGHDennisVALasaterBLPhilippMTInduction of pro- and anti-inflammatory cytokines by Borrelia burgdorferi lipoproteins in monocytes is mediated by CD14Infect. Immun.19996714014796289
  • GiambartolomeiGHDennisVAPhilippMTBorrelia burgdorferi stimulates the production of interleukin-10 in peripheral blood mononuclear cells from uninfected humans and rhesus monkeysInfect. Immun.19986626912697108257
  • GarciaRCMurgiaRCincoMComplement receptor 3 binds the Borrelia burgdorferi outer surface proteins OspA and OspB in an iC3b-independent mannerInfect. Immun.2005736138614210.1128/IAI.73.9.6138-6142.20051231105
  • NagaiYRequirement for MD-1 in cell surface expression of RP105/CD180 and B-cell responsiveness to lipopolysaccharideBlood2002991699170510.1182/blood.V99.5.1699
  • SchultzTEBlumenthalAThe RP105/MD-1 complex: molecular signaling mechanisms and pathophysiological implicationsJ. Leukoc. Biol.201710118319210.1189/jlb.2VMR1215-582R
  • OgataHThe toll-like receptor protein RP105 regulates lipopolysaccharide signaling in B cellsJ. Exp. Med.2000192232910.1084/jem.192.1.231887709
  • ChungEYKimSJMaXJRegulation of cytokine production during phagocytosis of apoptotic cellsCell Res.20061615416110.1038/sj.cr.7310021