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Emerging Microbes & Infections Volume 7, 2018 - Issue 1

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Original Articles

Cross-reactive mouse monoclonal antibodies raised against the hemagglutinin of A/Shanghai/1/2013 (H7N9) protect against novel H7 virus isolates in the mouse model

Daniel StadlbauerDepartment of MicrobiologyIcahn School of Medicine at Mount SinaiNew YorkNYUSA;Department of BiotechnologyUniversity of Natural Resources and Life SciencesViennaAustria

Fatima AmanatDepartment of MicrobiologyIcahn School of Medicine at Mount SinaiNew YorkNYUSA

Shirin StrohmeierDepartment of MicrobiologyIcahn School of Medicine at Mount SinaiNew YorkNYUSA

Raffael NachbagauerDepartment of MicrobiologyIcahn School of Medicine at Mount SinaiNew YorkNYUSA

http://orcid.org/0000-0001-5568-5420

Florian KrammerDepartment of MicrobiologyIcahn School of Medicine at Mount SinaiNew YorkNYUSACorrespondence[email protected]

http://orcid.org/0000-0003-4121-776X

Pages 1-12 | Received 16 Mar 2018, Accepted 24 May 2018, Published online: 20 Jun 2018

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https://doi.org/10.1038/s41426-018-0115-0
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References

MolinariNAMThe annual impact of seasonal influenza in the US: measuring disease burden and costsVaccine200725 5086 509610.1016/j.vaccine.2007.03.046
PubMed Web of Science ®Google Scholar
http://www.who.int/mediacentre/factsheets/fs211/en/ (2017).
Google Scholar
DanqiBLiZLiuQRichtJAH7N9 avian influenza A virus in China: a short report on its circulation, drug resistant mutants and novel antiviral drugsExpert. Rev. Anti. Infect. Ther.20171572372710.1080/14787210.2017.13534196101659
PubMed Web of Science ®Google Scholar
Organisation, W. H. (2017). http://www.who.int/influenza/human_animal_interface/Influenza_Summary_IRA_HA_interface_09_27_2017.pdf?ua=1
Google Scholar
TannerWDTothDJGundlapalliAVThe pandemic potential of avian influenza A(H7N9) virus: a reviewEpidemiol. Infect.20151433359337410.1017/S0950268815001570
PubMed Web of Science ®Google Scholar
SubbaraoKAvian influenza H7N9 viruses: a rare second warningCell Res.2017281210.1038/cr.2017.154
PubMed Web of Science ®Google Scholar
YangLGenesis and spread of newly emerged highly pathogenic H7N9 avian viruses in Mainland ChinaJ Virol201791e01277175686710
PubMed Web of Science ®Google Scholar
WangDTwo outbreak sources of influenza A (H7N9) viruses have been established in ChinaJ. Virol.2016905561557310.1128/JVI.03173-154886776
PubMed Web of Science ®Google Scholar
KileJCUpdate: increase in human infections with novel Asian lineage avian influenza A(H7N9) viruses during the fifth epidemic—China, October 1, 2016–August 7, 2017Morb. Mortal. Wkly. Rep.20176692893210.15585/mmwr.mm6635a2
PubMed Web of Science ®Google Scholar
LeeDHTorchettiMKKillianMLSwayneDEDeep sequencing of H7N8 avian influenza viruses from surveillance zone supports H7N8 high pathogenicity avian influenza was limited to a single outbreak farm in Indiana during 2016Virology201750721621910.1016/j.virol.2017.04.025
PubMed Web of Science ®Google Scholar
Pantin-JackwoodMJStephensCBBertranKSwayneDESpackmanEThe pathogenesis of H7N8 low and highly pathogenic avian influenza viruses from the United States 2016 outbreak in chickens, turkeys and mallardsPLoS ONE201712e017726510.1371/journal.pone.01772655421793
PubMed Web of Science ®Google Scholar
Marinova-Petkova, A. et al. Avian influenza A(H7N2) virus in human exposed to sick cats, New York, USA, 2016. Emerg. Infect. Dis. 23, 2046–2049 (2017).
Google Scholar
NachbagauerRDefining the antibody cross-reactome directed against the influenza virus surface glycoproteinsNat. Immunol.20171846447310.1038/ni.36845360498
PubMed Web of Science ®Google Scholar
OsterholmMTBalleringKSKelleyNSMajor challenges in providing an effective and timely pandemic vaccine for influenza A(H7N9)JAMA20173092557255810.1001/jama.2013.6589
Google Scholar
ZhangWCo-infection with avian (H7N9) and pandemic (H1N1) 2009 influenza viruses, ChinaEmerg. Infect. Dis.20152171571810.3201/eid2104.1415604378472
PubMed Web of Science ®Google Scholar
CouchRBPatelSMWade-BowersCLNinoDA randomized clinical trial of an inactivated avian influenza A (H7N7) vaccinePLoS ONE20127e4970410.1371/journal.pone.00497043519847
PubMed Web of Science ®Google Scholar
CoxRJA phase I clinical trial of a PER.C6 cell grown influenza H7 virus vaccineVaccine2009271889189710.1016/j.vaccine.2009.01.116
PubMed Web of Science ®Google Scholar
KrammerFAn H7N1 influenza virus vaccine induces broadly reactive antibody responses against H7N9 in humansClin. Vaccin. Immunol.2014211153116310.1128/CVI.00272-14
PubMed Web of Science ®Google Scholar
StadlbauerDVaccination with a recombinant H7 hemagglutinin-based influenza virus vaccine induces broadly reactive antibodies in humans.mSphere20172e00502-1710.1128/mSphere.00502-175729220
PubMed Web of Science ®Google Scholar
RudenkoLH7N9 live attenuated influenza vaccine in healthy adults: a randomised, double-blind, placebo-controlled, phase 1 trialLancet Infect. Dis.20161630331010.1016/S1473-3099(15)00378-3
PubMed Web of Science ®Google Scholar
RudenkoLAssessment of human immune responses to H7 avian influenza virus of pandemic potential: results from a placebo-controlled, randomized double-blind phase I study of live attenuated H7N3 influenza vaccinePLoS ONE20149e8796210.1371/journal.pone.00879623922724
PubMed Web of Science ®Google Scholar
KrammerFCoxRJThe emergence of H7N9 viruses: a chance to redefine correlates of protection for influenza virus vaccinesExpert. Rev. Vaccin.2013121369137210.1586/14760584.2013.850036
PubMed Web of Science ®Google Scholar
CoxRJCorrelates of protection to influenza virus, where do we go from here?Hum. Vaccin. Immunother.2013940540810.4161/hv.229083859764
PubMed Web of Science ®Google Scholar
Henry DunandCJBoth neutralizing and non-neutralizing human H7N9 influenza vaccine-induced monoclonal antibodies confer protectionCell Host Microbe20161980081310.1016/j.chom.2016.05.0144901526
PubMed Web of Science ®Google Scholar
LeonPEOptimal activation of Fc-mediated effector functions by influenza virus hemagglutinin antibodies requires two points of contactProc. Natl. Acad. Sci. USA2016113E5944e595110.1073/pnas.16132251135056099
PubMed Web of Science ®Google Scholar
JacobsenHInfluenza virus hemagglutinin stalk-specific antibodies in human serum are a surrogate marker for in vivo protection in a serum transfer mouse challenge model.MBio20178e01463-1710.1128/mBio.01463-175605943
PubMed Web of Science ®Google Scholar
TanGSBroadly-reactive neutralizing and non-neutralizing antibodies directed against the H7 influenza virus hemagglutinin reveal divergent mechanisms of protectionPLoS Pathog.201612e100557810.1371/journal.ppat.10055784833315
PubMed Web of Science ®Google Scholar
Martínez-Sobrido, L. & García-Sastre, A. Generation of recombinant influenza virus from plasmid DNA. J. Vis. Exp. (2010).
Google Scholar
LiJHuman co-infection with avian and seasonal influenza viruses, ChinaEmerg. Infect. Dis.2014201953195510.3201/eid2011.1408974214318
PubMed Web of Science ®Google Scholar
WhiteMCLowenACImplications of segment mismatch for influenza A virus evolutionJ. Gen. Virol.20179931610.1099/jgv.0.0009895882089
PubMed Web of Science ®Google Scholar
StadlbauerDNachbagauerRMeadePKrammerFUniversal influenza virus vaccines: what can we learn from the human immune response following exposure to H7 subtype viruses?Front. Med.20171147147910.1007/s11684-017-0602-z
PubMed Web of Science ®Google Scholar
NachbagauerRKrammerFUniversal influenza virus vaccines and therapeutic antibodiesClin. Microbiol. Infect.20172322222810.1016/j.cmi.2017.02.0095389886
PubMed Web of Science ®Google Scholar
KrammerFPalesePAdvances in the development of influenza virus vaccinesNat. Rev. Drug. Discov.20151416718210.1038/nrd4529
PubMed Web of Science ®Google Scholar
SalazarGZhangNFuTMAnZAntibody therapies for the prevention and treatment of viral infectionsNPJ Vaccin.2017210.1038/s41541-017-0019-3
PubMed Web of Science ®Google Scholar
DiLilloDJPalesePWilsonPCRavetchJVBroadly neutralizing anti-influenza antibodies require Fc receptor engagement for in vivo protectionJ. Clin. Invest.201612660561010.1172/JCI844284731186
PubMed Web of Science ®Google Scholar
KrammerFDivergent H7 immunogens offer protection from H7N9 virus challengeJ. Virol.2014883976398510.1128/JVI.03095-133993735
PubMed Web of Science ®Google Scholar
SchmeisserFAntibodies to Antigenic Site A of Influenza H7 Hemagglutinin Provide Protection against H7N9 Challenge.PLoS ONE201510e011710810.1371/journal.pone.01171084309539
PubMed Web of Science ®Google Scholar
ChenZDevelopment of a high-yield live attenuated H7N9 influenza virus vaccine that provides protection against homologous and heterologous H7 wild-type viruses in ferretsJ. Virol.2014887016702310.1128/JVI.00100-144054345
PubMed Web of Science ®Google Scholar
MatsuokaYSafety evaluation in chickens of candidate human vaccines against potential pandemic strains of influenzaAvian Dis.20034792693010.1637/0005-2086-47.s3.926
PubMed Web of Science ®Google Scholar
BeareASSchildGCCraigJWTrials in man with live recombinants made from A/PR/8/34 (H0 N1) and wild H3 N2 influenza virusesLancet1975272973210.1016/S0140-6736(75)90720-5
PubMed Web of Science ®Google Scholar
RodriguezAAttenuated strains of influenza A viruses do not induce degradation of RNA polymerase IIJ. Virol.200983111661117410.1128/JVI.01439-092772756
PubMed Web of Science ®Google Scholar
CampbellPJThe M segment of the 2009 pandemic influenza virus confers increased neuraminidase activity, filamentous morphology, and efficient contact transmissibility to A/Puerto Rico/8/1934-based reassortant virusesJ. Virol.2014883802381410.1128/JVI.03607-133993553
PubMed Web of Science ®Google Scholar
BelserJAPathogenicity testing of influenza candidate vaccine viruses in the ferret modelVirology201751113514110.1016/j.virol.2017.08.0245791157
PubMed Web of Science ®Google Scholar
KrammerFA carboxy-terminal trimerization domain stabilizes conformational epitopes on the stalk domain of soluble recombinant hemagglutinin substratesPLoS ONE20127e4360310.1371/journal.pone.00436033426533
PubMed Web of Science ®Google Scholar
MargineIPalesePKrammerFExpression of functional recombinant hemagglutinin and neuraminidase proteins from the novel H7N9 influenza virus using the baculovirus expression system.J. Vis. Exp.201381e51112
Google Scholar
TanGSA pan-H1 anti-hemagglutinin monoclonal antibody with potent broad-spectrum efficacy in vivoJ. Virol.2012866179618810.1128/JVI.00469-123372189
PubMed Web of Science ®Google Scholar
DuehrJNovel cross-reactive monoclonal antibodies against Ebola virus glycoproteins show protection in a murine challenge model.J. Virol.201791e00652-1710.1128/JVI.00652-175533894
PubMed Web of Science ®Google Scholar
WuYA potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virusNat. Commun.2015610.1038/ncomms87084518248
Web of Science ®Google Scholar

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Cross-reactive mouse monoclonal antibodies raised against the hemagglutinin of A/Shanghai/1/2013 (H7N9) protect against novel H7 virus isolates in the mouse model

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Cross-reactive mouse monoclonal antibodies raised against the hemagglutinin of A/Shanghai/1/2013 (H7N9) protect against novel H7 virus isolates in the mouse model

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