13
Views
6
CrossRef citations to date
0
Altmetric
Original

The association between depression and isotretinoin use in acne

&
Pages 78-84 | Received 30 Apr 2002, Accepted 10 Sep 2002, Published online: 07 Aug 2009

References

  • Josefson D. Acne drug linked to severe depression. British Medical Journal 1998; 316: 723
  • Nguyen E H, Wolverton S E. Systemic retinoids. Comprehensive dermatologic drug therapy, S E Wolverton. Saunders, Philadelphia 2001; 269–310
  • Farrell L N, Strauss J S, Stranieri A M. The treatment of severe cystic acne with 13-cis-retinoic acid: evaluation of sebum production and the clinical response in a multiple-dose trial. Journal of the American Academy of Dermatology 1980; 3: 602–611
  • Mills C M, Marks R. Adverse reactions to oral retinoids. Drug Safety 1993; 9: 280–290
  • Bigby M, Stern R S. Adverse reactions to isotretinoin. Journal of the American Academy of Dermatology 1988; 18: 543–552
  • Hull P R, Demkiw-Bartel C. Isotretinoin use in acne: prospective evaluation of adverse events. Journal of Cutaneous Medicine and Surgery 2000; 4: 66–70
  • Lamberg L. Acne drug depression warnings highlight need for expert care. Journal of the American Medical Association 1998; 279: 1073
  • Byrne A, Hnatko G. Depression associated with isotretinoin therapy. Canadian Journal of Psychiatry 1995; 40: 567
  • Duke E, Guenther L. Psychiatric reactions to the retinoids. Canadian Journal of Dermatology 1993; 5: 467
  • Bravard P, Krug M, Rzeznick J C. Isotretinoin et depressoin, soyons vigilantes. Nouveau Dermatologie 1993; 12: 215
  • Gatti S, Serri F. Acute depression from isotretinoin. Journal of the American Academy of Dermatology 1991; 25: 132
  • Ng C H, Tam M M, Hook S J. Acne, isotretinoin treatment and acute depression. World Journal of Biological Psychiatry 2001; 2: 159–161
  • Ault A. Isotretinoin use may be linked with depression. Lancet 1998; 351: 730
  • Scheinman P L, Peck G L, Rubinow D R, DiGiovanna J J, Abangan D L, Ravin P D. Acute depression from isotretinoin. Journal of the American Academy of Dermatology 1990; 22: 1112–1114
  • Hazen P G, Carney J F, Walker A E, Stewart J J. Depression–a side effect of 13-cis-retinoic acid therapy. Journal of the American Academy of Dermatology 1983; 9: 278–279
  • Goulden V, Layton A M, Cunliffe W J. Long-term safety of isotretinoin in the treatment of acne vulgaris. British Journal of Dermatology 1994; 131: 360–363
  • Adverse Drug Reactions Advisory Committee (ADRAC). Depression and isotretinoin. Australian Adverse Drug Reactions Bulletin 1998; 17: 11
  • Wysowski D K, Pitts M, Beitz J. Depression and suicide in patients treated with isotretinoin. New England Journal of Medicine 2001; 344: 460
  • Koo J. The psychosocial impact of acne: patients' perception. Journal of the American Academy of Dermatology 1995; 32: 26–30
  • Gupta M A, Gupta A K. Depression and suicidal ideation in dermatology patients with acne, alopecia areata, atopic dermatitis and psoriasis. British Journal of Dermatology 1998; 139: 846–850
  • Wu S F, Kinder B N, Trunnell T N, Fulton J E. Role of anxiety and anger in acne patients: a relationship with the severity of the disorder. Journal of the American Academy of Dermatology 1988; 18: 325–333
  • Cotterill J A, Cunliffe W J. Suicide in dermatological patients. British Journal of Dermatology 1997; 137: 246–250
  • Krowchuk D P, Stancin T, Keskinen R, Walker R, Bass J, Anglin T M. The psychosocial effects of acne on adolescents. Pediatric Dermatology 1991; 8: 332–338
  • Kellett S C, Gawkrodger D J. The psychological and emotional impact of acne and the effect of treatment with isotretinoin. British Journal of Dermatology 1999; 140: 273–282
  • Rubinow D R, Peck G L, Squillace K M, Gantt G G. Reduced anxiety and depression in cystic acne patients after successful treatment with isotretinoin. Journal of the American Academy of Dermatology 1987; 17: 25–32
  • Macdonald Hull S, Cunliffe W J, Hughes B R. Treatment of the depressed and dysmorphophobic acne patient. Clinical and Experimental Dermatology 1991; 16: 210–211
  • Layton A M, Seukeron D, Cunliffe W J. Scarred for life. Dermatology 1997; 195: 29–33
  • Peck G L, DiGiovanna J J, Rubinow D R. Acute depression from isotretinoin, reply. Journal of the American Academy of Dermatology 1991; 25: 132
  • Jick S S, Kremers H M, Vasilakis-Scaramozza C. Isotretinoin use and risk of depression, psychotic symptoms, suicide, and attempted suicide. Archives of Dermatology 2000; 136: 1231–1236
  • Wysowski D K, Beitz J. Methodological limitations of the study ‘Isotretinoin use and risk of depression, psychotic symptoms, suicide, and attempted suicide’. Archives of Dermatology 2001; 137: 1102–1103
  • Ng C H, Tam M M, Celi E, Tate B, Schweitzer I. A prospective study of depressive symptoms and quality of life in acne vulgaris patients treated with isotretinoin compared to antibiotic and topical therapy. Australasian Journal of Dermatology 2002; 43: 262–268
  • Wysowski D K, Pitts M, Beitz J. An analysis of reports of depression and suicide in patients treated with isotretinoin. Journal of the American Academy of Dermatology 2001; 45: 515–519
  • Henderson S, Andrews G, Hall W. Australia's mental health: an overview of the general population survey. Australian and New Zealand Journal of Psychiatry 2000; 34: 197–205
  • Patton G C, Coffey C, Posterino J B, Wolfe R. Adolescent depressive disorder: a population-based study of ICD-10 symptoms. Australian and New Zealand Journal of Psychiatry 2000; 34: 741–747
  • Krezel W, Ghyselinck N, Samad T A, et al. Impaired locomotion and dopamine signalling in retinoid receptor mutant mice. Science 1998; 279: 863–867
  • Peck G L, DiGiovanna J J. The retinoids. Fizpatrick's dermatology in general medicine, 5th edn., I M Freedberg, et al. McGraw-Hill, New York 1999; 2810–2820
  • Feldman M H, Scglezinger N S. Benign intracranial hypertension associated with hypervitaminosis, A. Achives of Neurology 1970; 22: 1–7
  • Byrne A, Costello M, Greene E, Zibin T. Isotretinoin therapy depression–evidence for an association. Irish Journal of Psychological Medicine 1998; 15: 58–60

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.