Advanced search
Publication Cover
Current Eye Research Volume 20, 2000 - Issue 5
Submit an article Journal homepage
182
Views
30
CrossRef citations to date
0
Altmetric
Research Article

Isolation of primary open-angle glaucomatous trabecular meshwork cells from whole eye tissue

W. Daniel Stamer Departments of Ophthalmology and Pharmacology, The University of Arizona, Tucson, AZ, USA, Department of Ophthalmology, Duke University, Durham, NC, USA
,
Bruce C. Roberts Departments of Ophthalmology and Pharmacology, The University of Arizona, Tucson, AZ, USA, Department of Ophthalmology, Duke University, Durham, NC, USA
,
David L. Epstein Departments of Ophthalmology and Pharmacology, The University of Arizona, Tucson, AZ, USA, Department of Ophthalmology, Duke University, Durham, NC, USA
&
R. Rand Allingham Departments of Ophthalmology and Pharmacology, The University of Arizona, Tucson, AZ, USA, Department of Ophthalmology, Duke University, Durham, NC, USA
Pages 347-350 | Published online: 02 Jul 2009

References

  • Quigley HA, Hohman RM, Addicks EM, Massof, RW, Green, WR. Morphologic changes in the lamina cribrosa correlated with neural loss in open-angle glaucoma. Am J Ophthalmol. 1983;95:673–691.
  • Quigley HA. Open-angle glaucoma. New Eng J Med. 1993;328:1097–1106.
  • Quigley HA, Addicks EM. Chronic experimental glau-coma in primates. II Effect of extended intraocular pres-sure elevation on optic nerve head and axonal transport. Invest Ophthalmol Vis Sci. 1980;19:137–152.
  • Gaasterland D, Tanishima T, Kuwabara T. Axoplasmic flow during chronic experimental glaucoma. I. Light and electron microscopic studies of the monkey optic nervehead during development of glaucomatous cupping. Invest Ophthalmol Vis Sci. 1978;17:838–846.
  • Johnstone MA, Grant MD. Pressure-dependent changes in structures of the aqueous outflow system of human and monkey eyes. Am J Ophthalmol. 1973;75:365–383.
  • Bill A, Maepea 0. Mechanisms and routes of aqueous humor drainage. In: Principles and Practice of Ophthal-mology. Philadelphia: WB Saunders Co; 1975:206–226.
  • Alvarado J, Murphy C, Juster R. Trabecular meshwork cellularity in primary open-angle glaucoma and nonglau-comatous normals. Ophthalmol. 1984;91:564–579.
  • Lutjen-Drecoll E, Futa R, Rohen, JW. Ultrahistochemical studies on tangential sections of the trabecular meshwork in normal and glaucomatous eyes. Invest Ophthalmol Vis Sci. 1981;21:563–573.
  • Rohen JW. Why is intraocular pressure elevated in chronicsimple glaucoma? Anatomical considerations. Ophthal-mol. 1983;95:673–691.
  • Epstein DL. Open angle glaucoma: Why not a cure? (Editorial). Arch Ophthalmol. 1987;105:1187–1188.
  • Nguyen KP, Chung ML, Anderson PJ, Johnson M, Epstein, DL. Hydrogen peroxide removal by the calf aqueous outflow pathway. Invest Ophthalmol Vis Sci. 1988;29:976–981.
  • Weinstein BI, Gordon GG, Southren AL. Potentiation of glucocorticoid activity by 5 beta-dihydrocortisol: its role in glaucoma. Science. 1983;222: 172–173.
  • Southren AL, Gordon GG, Munnangi PR, Vittek J, Schwartz J, Monder C, Dunn WD, Weinstein BI. Altered cortisol metabolism in cells cultured from trabecular meshwork speciments obtained from patients with pri-mary open-angle glaucoma. Invest Ophthalmol Vis Sci. 1983;24:1413–1417.
  • Hernandez MR, Wenk EJ, Weinstein BI, Abumohor P, Podos SM, Dunn MW, Southren AL. Glucocorticoid target cells in human outflow pathway: autopsy and surgical specimens. Invest Ophthalmol Vis Sci. 1983;24: 1612–1616.
  • Polansky, JR. Alvarado, JA. Cellular Mechanisms Influ-encing the Aqueous Humor Outflow Pathway In: Prin-ciples and Practice of Ophthalmology. Philadelphia: WB Saunders Co; 1994:226–251.
  • Dickerson JE, Steely HT, English-Wright SL, Clark AF. The effect of dexamethasone on integrin and laminin expression in cultured human trabecular meshwork cells. Exp Eye Res. 1998;66:731–738.
  • Alvarado JA, Lui GM. Growth of human trabecular mesh-work cell lines from patients with POAG. Invest Ophthalmol Vis Sci (Suppl). 1986:27:714.
  • Epstein DL. Primary Open-Angle Glaucoma. In: Chan-dler and Grant's, Glaucoma. Baltimore: Williams and Wilkins; 1997:183–198.
  • Stamer WD, Seftor REB, Williams SK, Samaha HAM, Snyder RW. Isolation and culture of human trabecular meshwork cells by extracellular matrix digestion. Curr Eye Res. 1995;14:611–617.
  • Polansky JR, Weinreb RN, Baxter JD, Alvarado JA. Human trabecular cells: Establishment in tissue culture and growth characteristics. Invest Ophthalmol Vis Sci. 1979;18:1043–1049.
  • Polansky JR, Fauss DJ, Chen P, Chen H, Lutjen-Drecoll E, Johnson DH, Kurtz RM, Ma Z-D, Bloom E, Nguyen T.D. Cellular pharmacology and molecular biology of the trabecular meshwork inducible glucocorticoid re-sponse gene product. Ophthalmologica. 1997;211:126–139.
  • Stamer WD, Roberts BC, Howell DN, Epstein DL. Iso-lation, culture and characterization of endothelial cells from Schlemm's canal. Invest Ophthalmol Vis Sci. 1998;39:1804–1812.
  • Obrien ET. Personal communication. 1999.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.