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Current Eye Research Volume 17, 1998 - Issue 1
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Research Article

Adrenergic-mediated connexin43 phosphorylation in the ocular ciliary epithelium

Jonathan Sears Departments of Ophthalmology, Emory Eye Center, Emory University School of Medicine, Atlanta, GA, USA and Miyazaki Medical College, Miyazaki, Japan and Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, CT, USA
,
Tohru Nakano Departments of Ophthalmology, Emory Eye Center, Emory University School of Medicine, Atlanta, GA, USA and Miyazaki Medical College, Miyazaki, Japan and Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, CT, USA
&
Marvin Sears Departments of Ophthalmology, Emory Eye Center, Emory University School of Medicine, Atlanta, GA, USA and Miyazaki Medical College, Miyazaki, Japan and Department of Ophthalmology and Visual Science, Yale University School of Medicine, New Haven, CT, USA
Pages 104-107 | Published online: 02 Jul 2009

References

  • Raviola, G. and Raviola, E. (1978) Intercellular junctions in the ciliary epithelium. Invest. Ophthalmol. Vis. Sci. 17, 958–981.
  • Coca-Prados, M., Ghosh, S., Gilula, N. B. and Kumar, N. M. (1992) Expression and cellular distribution of the a 1 gap junction gene product in the ocular pigmented cili-ary epithelium. Curr. Eye Res. 11, 113–122.
  • Ping Shi, X., Zamudio, A. C., Candia, 0. A. and Wolosin, J. M. (1996) Adreno-cholinergic modulation of junctional communications between the pigmented and nonpig-mented layers of the ciliary body epithelium. Invest. Oph-thalmol. Vis. Sci. 37,1037–1046.
  • Musil, L. S., Beyer, E. C. and Goodenough, D. A. (1990) Expression of the gap junction protein connexin43 in embryonic chick lens: molecular cloning, ultrastructural localization, and post-translational phosphorylation. I Membr Biol. 116, 163–175.
  • Crow, D. S., Beyer, E. C., Paul, D. L., Kobe, S. S. and Lau, A. F. (1990) Phosphorylation of connexin43 gap junction protein in uninfected and Rous sarcoma virus-transformed mammalian fibroblasts. MoL Cell Biol. 10, 1754–1763.
  • Laird, D. W. and Revel, J.-P. (1990) Biochemical and immunochemical analysis of connexin43 in rat heart gap junction membranes. J. Cell Sci 97, 109–117.
  • Musil, L. S. and Goodenough, D. A. (1991) Biochemical analysis of connexin43 intracellular transport, phosphory-lation, and assembly into gap junctional plaques. J. Cell Biol. 115, 1357–1374.
  • Stagg, R. B. and Fletcher, W. H. (1990) The hormone-induced regulation of contact-dependent cell-cell commu-nication by phosphorylation. Endocr. Rev. 11, 302–325.
  • Oh, S. Y., Grupen, C. G. and Murray, A. W. (1991) Phorbol ester induces phosphorylation and down regulation of connexin43 in WB cells. Biochem. Biophys. Acta, 1094,243–245.
  • Brissette, J. C., Kumar, N. M., Gilula, N. B. and Dotto, P. (1991) The tumor promoter 12-o-tetradecanoylphorbol-13-acetate and the ras oncogene modulate expression and phosphorylation of gap junctional proteins. MoL Cell Biol. 105, 5364–5371.
  • Reynhout, J. K., Lampe, P. D. and Johnson, R. G. (1992) An activator of protein kinase C inhibits junction commu-nication between cultured bovine epithelial cells. Exp. Cell Res. 198, 337–342.
  • Godwin, A. J., Green, L. M., Walsh, M. P., McDonald, J. R., Walsh, D. A. and Fletcher, W. H. (1993) In situ regu-lation of cell-cell communication by the cAMP-dependent protein kinase and protein kinase C. MoL Cell Biochem. 127/128, 293–307.
  • Warn-Cramer, B. J., Lampe, P. D., Kurata, W. E., Kane-mitsu, M. Y., Loo, L. W., Eckhart, W. and Lau, A. F. (1996) Characterization of the mitogen-activated protein kinase phosphorylation sites on the connexin43 gap junction pro-tein. Biol. Chem. 271 (7), 3779–3786.
  • Mikalsen, S. 0., Husoy, T. and Sanner, T. (1995) Modula-tion of gap junctional intercellular communication by phosphorylation: effects of growth factors, kinase activa-tors and phosphatase inhibitors. Frog. Clin. Biol. Res. 391, 425–438.
  • Kwak, B. R, Hermans, M. M., De Jonge, H. R, Lohmaim, S. M., Jongsma, H. J. and Chanson, M. (1995) Differential regu-lation of distinct types of gap junction channels by similar phosphorylating conditions. MoL Biol. Cell, 12, 1707–1719.
  • Sears, M. L., Yamada, E., Cummins, D., Mori, N., Mead, A. and Murakami, M. (1991) The isolated ciliary bilayer is useful for studies of aqueous humor formation. Trans. Am. Ophthalmol. Soc. 89, 131–154.
  • Yoshimura, N., Mittag, T. and Podos, S. M. (1989) Cal-cium-dependent phosphorylation of proteins in rabbit cili-ary processes. Invest. Ophthalmol. Vis. Sci. 30, 723–730.
  • Begum, N. and Ragolia, L. J. (1996) cAMP counter-regu-lates insulin-mediated protein phosphatase-2A inactivation in rat skeletal muscle cells. Bio. Chem. 271, 31166–31171.

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