465
Views
30
CrossRef citations to date
0
Altmetric
Research Article

Analgesic Properties of Umbellatine from Psychotria umbellata

, , &
Pages 336-341 | Published online: 29 Sep 2008

References

  • Abbott FV, Young SN (1988): Effect of 5-hydroxitriptamine precursors on morphine analgesia in the formalin test. Pharmacol Biochem Behav 31: 855–860.
  • Amador TA, Verotta L, Nunes DS, Elisabetsky E (2000): Antinociceptive profile of hodgkinsine. Planta Med 66: 1–3.
  • Amador TA, Verotta L, Nunes DS, Elisabetsky E (2001): Involvement of NMDA receptors in the analgesic proper-ties of psychotridine. Phytomedicine 8: 202–206.
  • Balandrin MF, Klocke JA, Wurtele, ES, Bollinger WH (1985): Natural plant chemicals: Sources of industrial and medici-nal materials. Science 228: 1154–1160.
  • Chaplan SR, Malmberg AB, Yaksh TL (1997): Efficacy of spinal NMDA receptor antagonism in formalin hyperalgesia and nerve injury evoked allodynia in the rat. J Pharmacol Exp Ther 280: 829–838.
  • Coderre TJ, Melzack R (1992): The contribution of excitatory amino acids to central sensitization and persistent nocicep-tion after formalin-induced tissue injury. J Neuroscience 12: 3665–3670.
  • Dalmmeier K, Carlini EA (1981): Anesthesic hypothermic, myorrelaxant and anticonvulsivant effect of synthetic eugenol derivatives and natural analogues. Pharmacology 22: 113–27.
  • Dickenson AH (1997): NMDA receptor antagonists: Interac-tions with opioids. Acta Anaesthesiol Scand 41: 112–115.
  • Eddy NB, Touchberry CS, Lieberman JE (1950): Synthetic anal-gesic. I. Methadone isomer and derivatives. J Pharmacol Exp Ther 98: 121–137.
  • Elisabetsky E, Amador TA, Leal MB, Nunes DS, Carvalho AC, Verona L (1997): Merging ethriopharmacology with chemotaxonomy: An approach to unveil bioactive natural products. The case of Psychotria alkaloids as potential anal-gesics. Ciência e Cultura 49: 378–385.
  • Gardmark M, Höglund AU, Hammarlund-Udenaes M (1998): Aspects on tail-flick, hot-plate and electrical stimulation tests for morphine antinociception. Pharmacol Toxicol 83: 252–258.
  • Hunskaar S, Hole K (1987): The formalin test in mice: Disso-ciation between inflamatory and non-inflamatory pain. Pain 30: 103–114.
  • Hunter JC, Singh L (1994): Role of excitatory amino acid recep-tors in the mediation of the nociceptive response to forma-lin in the rat. Neuroscience Lett 174: 217–221.
  • Kerber VA (1999): Arialise dos alcalóides de Psychotria brachiceras Mull. Arg. e Psychotria umbellata Vell., e o estabelecimento e caracterização de cultura de células de P umbellata Vell. Tese de doutorado, Curso de P6s-Graduação em Ciencias Farmaceuticas. Universidade Federal do Rio Grande do Sul.
  • Leal MB, Elisabetsky E (1996): Opioid-like activity of Psycho-tria brachypoda. Int .1 Pharmacog 34: 267–272.
  • Mao J, Price DD, Hayes RL et al. (1992): Differential roles of
  • NMDA and non-NMDA receptor activation in induction and maintenance of thermal hyperalgesia in rats with painful peripheral mononeuropathy. Brain Res 598: 271–278.
  • Netto CA, Siegried B, Izquierdo 1(1987): Analgesia induced by exposure to a novel environment in rats: Effect of concur-rent and post-training stressful stimulation. Behavioral Neural Biol 48: 304–309.
  • Perkins M, Dray A (1996): Novel pharmacological strategies for analgesia, Ann Rheumatic Dis 55: 715–722.
  • Sakaruda T, Katsumata K, Tan-No K, Sakurada S, Kisara K (1992): The capsaicin test in mice for evaluating tachykinin antagonists in the spinal cord. Neuropharmacology 31: 1279–1285.
  • Sakurada T, Wako K, Sugiyama A, Sakurada C, Tan-No K, Kisara K (1998): Involvement of spinal NMDA receptors in capsaicin-induced nociception. Pharm Biochem Behav 59: 339–345.
  • Schultes RE, Raffauf RF (1990): The Healing Forest: Medici-nal and Toxic Plants of the Northwest Amazonia. Portland, Dioscorides Press, pp. 392–396.
  • Stamford JA (1995): Descending control of pain. Brit J Anaes-thesia 75: 217–227.
  • Trujillo KA, Akil H (1991): Inhibition of morphine tolerance and dependence by the NMDA receptor antagonist MK-801. Science 251: 85–87.
  • Wiesenfeld-Hallin Z (1998): Combined opioid-NMDA antago-nist therapies: What advantages do they offer for the control of pain syndromes? Drugs 55: 1–4.
  • Woolfe G, Mac Donald AD (1944): The evaluation of analgesic action of petidine hydrochloride (Bemerol). J Pharmacol Exp Ther 80: 300–307.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.