Dose–response association between serum uric acid levels and incident hypertension: a systematic review and meta-analysis of 17 prospective cohort studies of 32 thousand participants

References

• James SL, Abate D, Abate KH, et al. Global, regional, and national incidence, prevalence, and years lived with disability for 354 diseases and injuries for 195 countries and territories, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018;392(10159):1789–1858.
   PubMed Web of Science ®Google Scholar
• Poulter NR, Prabhakaran D, Caulfield M. Hypertension. Lancet. 2015;386(9995):801–812.
   PubMed Web of Science ®Google Scholar
• Kearney PM, Whelton M, Reynolds K, et al. Global burden of hypertension: analysis of worldwide data. Lancet. 2005;365(9455):217–223.
   PubMed Web of Science ®Google Scholar
• Olsen MH, Spencer S. A global perspective on hypertension: a lancet commission. Lancet. 2015;386(9994):637–638.
   PubMed Web of Science ®Google Scholar
• Ling L, Yanqiu W, Yaojun S, et al. Relationship between uric acid level and essential hypertension in Chinese population: a meta-analysis. J Youjiang Med Univer National. 2018;40:257–262.
   Google Scholar
• Zhang W, Sun K, Yang Y, et al. Plasma uric acid and hypertension in a Chinese community: prospective study and metaanalysis. Clin Chem. 2009;55(11):2026–2034.
   PubMed Web of Science ®Google Scholar
• Lu Z, Dong B, Wu H, et al. Serum uric acid level in primary hypertension among Chinese nonagenarians/centenarians. J Hum Hypertens. 2009;23(2):113–121.
   PubMed Web of Science ®Google Scholar
• Li X, Meng X, Timofeeva M, et al. Serum uric acid levels and multiple health outcomes: umbrella review of evidence from observational studies, randomised controlled trials, and Mendelian randomisation studies. BMJ. 2017;357:j2376.
   PubMed Web of Science ®Google Scholar
• Wang J, Qin T, Chen J, et al. Hyperuricemia and risk of incident hypertension: a systematic review and meta-analysis of observational studies. PLOS One. 2014;9(12):e114259
   PubMed Web of Science ®Google Scholar
• Grayson PC, Kim SY, LaValley M, et al. Hyperuricemia and incident hypertension: a systematic review and meta-analysis. Arthritis Care Res. 2011;63(1):102–110.
   PubMed Web of Science ®Google Scholar
• Sundström J, Sullivan L, D’Agostino RB, et al. Relations of serum uric acid to longitudinal blood pressure tracking and hypertension incidence. Hypertension. 2005;45(1):28–33.
   PubMed Web of Science ®Google Scholar
• Wells G, Shea B, O’Connell D, et al. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. 2019; [cited 2019, Dec 1]. Available from: http://www.ohri.ca/programs/clinical_epidemiology/oxford.asp.
   Google Scholar
• Orsini N, Li R, Wolk A, et al. Meta-analysis for linear and nonlinear dose-response relations: examples, an evaluation of approximations, and software. Am J Epidemiol. 2012;175(1):66–73.
   PubMed Web of Science ®Google Scholar
• Higgins JP, Thompson SG, Deeks JJ, et al. Measuring inconsistency in meta-analyses. BMJ. 2003;327(7414):557–560.
   PubMed Web of Science ®Google Scholar
• Egger M, Davey SG, Schneider M, et al. Bias in meta-analysis detected by a simple, graphical test. BMJ. 1997;315(7109):629–634.
   PubMed Web of Science ®Google Scholar
• Lee SW, Kim HC, Nam C, et al. Age-differential association between serum uric acid and incident hypertension. Hypertens Res. 2019;42(3):428–437.
   PubMed Web of Science ®Google Scholar
• Goncalves JP, Oliveira A, Severo M, et al. Cross-sectional and longitudinal associations between serum uric acid and metabolic syndrome. Endocrine. 2012;41(3):450–457.
   PubMed Web of Science ®Google Scholar
• Chien KL, Hsu HC, Su TC, et al. Prediction models for the risk of new-onset hypertension in ethnic Chinese in Taiwan. J Hum Hypertens. 2011;25(5):294–303.
   PubMed Web of Science ®Google Scholar
• Mellen PB, Bleyer AJ, Erlinger TP, et al. Serum uric acid predicts incident hypertension in a biethnic cohort: the atherosclerosis risk in communities study. Hypertension. 2006;48(6):1037–1042.
   PubMed Web of Science ®Google Scholar
• Dyer AR, Liu K, Walsh M, et al. Ten-year incidence of elevated blood pressure and its predictors: the CARDIA study. Coronary artery risk development in (young) adults. J Hum Hypertens. 1999;13(1):13–21.
   PubMed Web of Science ®Google Scholar
• Cao Z, Cheng Y, Li S, et al. Mediation of the effect of serum uric acid on the risk of developing hypertension: a population-based cohort study. J Transl Med. 2019;17(1):202.
   PubMed Web of Science ®Google Scholar
• Chen Q, Yin YJ, Chen WY, et al. Assessment of the association between serum uric acid levels and the incidence of hypertension in nonmetabolic syndrome subjects: a prospective observational study. Medicine (Baltimore. 2018;97(6):e9765.
   PubMed Web of Science ®Google Scholar
• Cui LF, Shi HJ, Wu SL, et al. Association of serum uric acid and risk of hypertension in adults: a prospective study of Kailuan Corporation cohort. Clin Rheumatol. 2017;36(5):1103–1110.
   PubMed Web of Science ®Google Scholar
• Sung KC, Byrne CD, Ryu S, et al. Baseline and change in uric acid concentration over time are associated with incident hypertension in large Korean Cohort. Am J Hypertens. 2017;30(1):42–50.
   PubMed Web of Science ®Google Scholar
• Leiba A, Vinker S, Dinour D, et al. Uric acid levels within the normal range predict increased risk of hypertension: a cohort study. J Am Soc Hypertens. 2015;9(8):600–609.
   PubMed Web of Science ®Google Scholar
• Nagahama K, Inoue T, Kohagura K, et al. Associations between serum uric acid levels and the incidence of hypertension and metabolic syndrome: a 4-year follow-up study of a large screened cohort in Okinawa, Japan. Hypertens Res. 2015;38(3):213–218.
   PubMed Web of Science ®Google Scholar
• Takase H, Kimura G, Dohi Y. Uric acid levels predict future blood pressure and new onset hypertension in the general Japanese population. J Hum Hypertens. 2014;28(9):529–534.
   PubMed Web of Science ®Google Scholar
• Yang T, Chu CH, Bai CH, et al. Uric acid concentration as a risk marker for blood pressure progression and incident hypertension: a Chinese cohort study. Metab Clin Exp. 2012;61(12):1747–1755.
   PubMed Web of Science ®Google Scholar
• Shankar A, Klein R, Klein BEK, et al. The association between serum uric acid level and long-term incidence of hypertension: population-based cohort study. J Hum Hypertens. 2006;20(12):937–945.
   PubMed Web of Science ®Google Scholar
• Taniguchi Y, Hayashi T, Tsumura K, et al. Serum uric acid and the risk for hypertension and type 2 diabetes in Japanese men: the Osaka health survey. J Hypertens. 2001;19:1209–1215.
   PubMed Web of Science ®Google Scholar
• Wu XW, Muzny DM, Lee CC, et al. Two independent mutational events in the loss of urate oxidase during hominoid evolution. J Mol Evol. 1992;34(1):78–84.
   PubMed Web of Science ®Google Scholar
• Feig DI, Kang D, Nakagawa T, et al. Uric acid and hypertension. Curr Hypertens Rep. 2006;8(2):111–115.
   PubMed Web of Science ®Google Scholar
• Johnson RJ, Herrera-Acosta J, Schreiner GF, et al. Subtle acquired renal injury as a mechanism of salt-sensitive hypertension. N Engl J Med. 2002;346(12):913–923.
   PubMed Web of Science ®Google Scholar
• M M, J H, Yg K, et al. Elevated uric acid increases blood pressure in the rat by a novel crystal-independent mechanism. Hypertension. 2001;38:1101–1106.
   PubMed Web of Science ®Google Scholar
• Xie JX, Hayek SS. Is it time to find a role for uric acid levels in the prevention and management of hypertension. Am J Hypertens. 2017;30(1):16–18.
   PubMed Web of Science ®Google Scholar
• Gagliardi ACM, Miname MH, Santos RD. Uric acid: a marker of increased cardiovascular risk. Atherosclerosis. 2009;202(1):11–17.
   PubMed Web of Science ®Google Scholar
• Feig DI, Mazzali M, Kang D, et al. Serum uric acid: a risk factor and a target for treatment? J Am Soc Nephrol. 2006;17(4 Suppl 2):S69–S73.
   PubMed Web of Science ®Google Scholar