224
Views
5
CrossRef citations to date
0
Altmetric
Case Report

Hydrogen peroxide in orthopaedic surgery – is it worth the risk?

, , &

References

  • Acharya A, Wilson J, Timperley J. Operative technique: Femur. In: Ling RSM, editor. The Exeter Hip. Exeter, UK: Exeter Hip Publishing; 2010. p. 185–194.
  • Chhabra R, Pathak A, Ray P. Fatal posterior fossa pneumocephalus due to hydrogen peroxide irrigation of lumbar wound. Br J Neurosurg. 2000;14:549–551.
  • Haller G, Faltin-Traub E, Faltin D, et al. Oxygen embolism after hydrogen peroxide irrigation of a vulvar abscess. Br J Anaesth. 2002;88:597–599.
  • Reid C, Alcock M, Penn D. Hydrogen peroxide – a party trick from the past? Anaesth Intensive Care. 2011;39:1004–1008.
  • Dahl J, Pallesen U. Tooth bleaching – a critical review of the biological aspects. Crit Rev Oral Biol Med. 2003;14:292–304.
  • Watt B, Proudfoot A, Vale J. Hydrogen peroxide poisoning. Toxicol Rev. 2004;23:51–57.
  • Mullins M, Beltran J. Acute cerebral gas embolism from hydrogen peroxide ingestion successfully treated with hyperbaric oxygen. J Toxicol Clin Toxicol. 1998;36:253–256.
  • Sierra E, Timperley J, Gie G. Contemporary cementing technique and mortality during and after exeter total hip arthroplasty. J Arthroplasty. 2009;24:325–332.
  • Howells RJ, Salmon JM, McCullough KG. The effect of irrigating solutions on the strength of the cement-bone interface. Aust NZ J Surg. 1992;62:215–218.
  • Ackland DC, Yap V, Ackland ML, et al. Pulse-lavage brushing followed by hydrogen peroxide-gauze packing for bone-bed preparation in cemented total hip arthroplasty: a bovine model. J Orthop Surg. 2009;17:296–300.
  • Guerin SR, MacNiochaill R, O’Reilly P, et al. A comparative study of the effect of hydrogen peroxide versus normal saline on the strength of the bone-cement interface. Biomed Mater Eng. 2007;17:379–386.
  • Kalloo A, Hill S, Wadwa KS, et al. The utility of hydrogen peroxide in the management of acute gastrointestinal bleeding (AGIB) in a canine model: a placebo controlled randomized trial. Am J Gastroenterol. 1996;91:1915.
  • Belisario MA, Tafuri S, Di Domenico C, et al. H(2)O(2) activity on platelet adhesion to fibrinogen and protein tyrosine phosphorylation. Biochim Biophys Acta. 2000;1495:183–193.
  • Warlick CA, Mouli SK, Allaf ME, et al. Bladder irrigation using hydrogen peroxide for clot evacuation. Urology. 2006;68:1331–1332.
  • Bannister GC, Young SK, Baker AS, et al. Control of bleeding in cemented arthroplasty. J Bone Joint Surg Br. 1990;72:444–446.
  • Anglen JO. Wound irrigation in musculoskeletal injury. J Am Acad Orthop Surg. 2001;9:219–226.
  • Taylor GJ, Leeming JP, Bannister GC. Effect of antiseptics, ultraviolet light and lavage on airborne bacteria in a model wound. J Bone Joint Surg Br. 1993;75:724–730.
  • Crowley DJ, Kanakaris NK, Giannoudis PV. Irrigation of the wounds in open fractures. J Bone Joint Surg Br. 2007;89:580–585.
  • Konrad C, Schüpfer G, Wietlisbach M. Oxygen embolism after use of hydrogen peroxide in thoracic surgery. Schweiz Med Wochenschr. 1997;127:1871–1874.
  • Henley N, Carlson DA, Kaehr DM, et al. Air embolism associated with irrigation of external fixator pin sites with hydrogen peroxide. A report of two cases. J Bone Joint Surg Am. 2004;86A:821–822.
  • Timperley AJ, Bracey DJ. Cardiac arrest following the use of hydrogen peroxide during arthroplasty. J Arthroplasty 1989;4:369–370.
  • McNicol L, Mackay P. Anaesthesia-related morbidity in Victoria: a report from 1990 to 2005. Anaesth Intensive Care. 2010;38:837–848.
  • Kaysinger K, Nicholson N, Ramp W, et al. Toxic effects of wound irrigation solutions on cultured tibiae and osteoblasts. J Orthop Trauma. 1995;9:303–311.
  • Röhner E, Kolar P, Seeger JB, et al. Toxicity of antiseptics against chondrocytes: what is best for the cartilage in septic joint surgery? Int Orthop. 2011;35:1719–1723.
  • Wilson JR, Mills JG, Prather ID, et al. A toxicity index of skin and wound cleansers used on in vitro fibroblasts and keratinocytes. Adv Skin Wound Care. 2005;18:373–378.
  • Shigematsu M, Kitajima M, Ogawa K, et al. Effects of hydrogen peroxide solutions on artificial hip joint implants. J Arthroplasty. 2005;20:639–646.
  • Mut M, Yemisci M, Gursoy-Ozdemir Y, et al. Hydrogen peroxide-induced stroke: elucidation of the mechanism in vivo. J Neurosurg. 2009;110:94–100.
  • Muth CM, Shank ES. Gas embolism. N Engl J Med. 2000;342:476–482.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.