853
Views
101
CrossRef citations to date
0
Altmetric
Research Article

Increases in callus formation and mechanical strength of healing fractures in old rats treated with parathyroid hormone

, , &
Pages 304-307 | Published online: 08 Jul 2009

  • Andreassen T T, Ejersled C, Oxlund H. Intermittent parathyroid hormone (1-34) treatment increases callus formation and mechanical strength of healing rat fractures. J Bone Miner Res 1999: 14 (6): 960-8.
  • Andreassen T T. Oxlund H. The influence of combined parathyroid hormone and growth hormone treatment on conical bone in aged ovariectomized rats. J Bone Miner Res 2000: 15(11): 2266-75.
  • Bostrom M P G, Gamrudt S C. Asruis P, Vickery B H, Hill E, Avnur Z. Waters R V. Parathyroid hormone-related protein analog RS-66271 is an effective therapy for impaired hone healing in rabbits on corticosteroid therapy. Bone 2000: 26(5):437-42.
  • Ejersted C, Andreassen T T, Oxlund H., Jørgensen P H, Bak B. Häggblad J, Tøming O, Nilsson M H L. Human parathyroid hormone (1-34) and (1-84) increase the mechanical strength and thickness of cortical hone in rats. J Bone Miner Res 1993: 8 (9): 1097-101.
  • Ejersted C, Oxlund H, Andreassen T T. Bisphosphonate maintains parathyroid hormone (1-34) induced conical hone mass and mechanical competence in old rats. Caleif Tissue Int 1998; 62 (4): 316-22.
  • Fleet J C, Cashman K, Cox K, Rosen V. The effects of aging on the bone inductive activity of recombinant human bone morphogenetic protein-2 Endocrinology 1996; 137 (11): 4605-10.
  • Hober G, Majeska R J, Lundy M W, Hartke J R, Einhorn T A. Parathyroid hormone enhances fracture healing. A preliminary report. Clin Orthop 1999; 366: 258-63.
  • Kim H W, Jahng J S. Effect of intermittent administration of parathyroid hormone on fracture healing in ovariectomized rats. Iowa Orthop J 1999; 19: 71-7.
  • Liang C T, Barnes J, Seedor J G, Quartuccio H A, Bolander M, Jeffrey J J, Rodan G A. Impaired bone activity in aged rats: alterations at the cellular and molecular levels. Bone 1992; 13(6): 435-41.
  • Mosckilde L, Daniesen C C, Sogaard C H, McOsker J E, Wronski T J. The anabolic effects of parathyroid hormone on cortical bone mass, dimensions and strength-assessed in a sexually mature, ovariectomized rat model. Bone 1995: 16 (2): 223-30.
  • Quarto R, Thomas D, Liang C T. Bone progenitor cell deficits and the age-associated decline in bone repair capacity. Caleif Tissue Int 1995; 56 (2): 123-9.
  • Roholl P J M, Blauw E, Zurcher C, Dormans J A M A, Theuns H M. Evidenee for a diminished maturation of preosteoblasts into osteoblasts during aging in rats: an ultrastructural analysis. J Bone Miner Res 1994; 9 (3): 355-66.
  • Skripitz R, Andreassen T T, Aspenberg P. Parathyroid hormone (1-34) increases the density of rat cancelous bone in a bone chamber. J Bone Joint Surg (Br) 2000; 82 (1): 138-41.
  • Wronski T J, Yen C-E, Qi H, Dann L M. Parathyroid hormone is more effective than estrogen or bisphosphonates for restoration of lost hone mass in ovariectomized rats. Endocrinology 1993; 132(2): 823-31.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.