Immune-mediated Hearing Loss: Basic Mechanisms and Options for Therapy

References

• McCabe BF. Autoimmune sensorineural hearing loss. Ann Otol Rhinol Laryngol 1979; 88: 585–9.
   PubMed Web of Science ®Google Scholar
• Moskowitz D, Lee KJ, Smith HW. Steroid use in idiopathic sudden sensorineural hearing loss. Laryngo-scope 1984; 94: 664–6.
   Google Scholar
• Hughes GB, Barna B, Kinner S, Calabrese L, Hamid M, Nalepa NJ. Autoimmune endolymphatic hydrops: a five-year review. Otolaryngol Head Neck Surg 1988; 98: 221–5.
   PubMed Web of Science ®Google Scholar
• Ariyusa L, Byl F, Sprague M, Adour K. The beneficial effects of methylprednisone in acute vestibular vertigo. Arch Otolaryngol Head Neck Surg 1990; 166: 700–3.
   Google Scholar
• Harris JP, Ryan AF. Immunobiology of the inner ear. Am J Otolaryngol 1984; 5: 418–25.
   PubMed Web of Science ®Google Scholar
• Harris JP, Woolf N, Ryan AF. The elaboration of systemic immunity following inner ear immunization. Am J Otolaryngol 1985; 6: 148–52.
   Google Scholar
• Neumann H. The immunological microenvironment in the CNS: implications on neuronal cell death and survival. J Neural Transm Suppl 2000; 59: 59–68.
   PubMedGoogle Scholar
• Woolf NK, Harris JP. Cochlear pathophysiology asso-ciated with inner ear immune responses. Acta Otolar-yngol (Stockh) 1986; 102: 353–64.
   PubMed Web of Science ®Google Scholar
• Ma C, Billings P, Harris JP, Keithley EM. Characteri-zation of an experimentally induced inner ear immune response. Laryngoscope 2000; 110: 451–6.
   PubMedGoogle Scholar
• Harris JP. Immunology of the inner ear: response of the inner ear to antigen challenge. Otolaryngol Head Neck Surg 1983; 91: 18–23.
   PubMed Web of Science ®Google Scholar
• Woolf N, Harris JP, Ryan AF, Butler DM, Richman DD. Hearing loss in experimental cytomegalovirus in-fection of the guinea pig inner ear: prevention by systemic immunity. Ann Otol Rhinol Laryngol 1985; 94: 350–6.
   Google Scholar
• Keithley EM, Harris JP. Late sequelae of cochlear infection. Laryngoscope 1996; 106: 341–5.
   PubMedGoogle Scholar
• Harris JP, Fukuda S, Keithley EM. Spiral modiolar vein: its importance in inner ear inflammation. Acta Otolaryngol (Stockh) 1990; 110: 357–65.
   Google Scholar
• Stearns GS, Keithley EM, Harris JP. Development of high endothelial venule-like characteristics in the spiral modiolar vein induced by viral labyrinthitis. Laryngo-scope 1993; 103: 890–8.
   Google Scholar
• Takahashi M, Harris JP. Analysis of immunocom-petent cells following inner ear immunostimulation. Laryngoscope 1988; 98: 1133–8.
   PubMed Web of Science ®Google Scholar
• Gloddek B, Ryan AF, Harris JP. Homing of lymphocytes to the inner ear. Acta Otolaryngol (Stockh) 1991; 111: 1051–9.
   PubMed Web of Science ®Google Scholar
• Tomiyama S, Harris JP. The role of the endolymphatic sac in inner ear immunity. Acta Otolaryngol (Stockh) 1987; 103: 182–8.
   Web of Science ®Google Scholar
• Takahashi M, Harris JP. Anatomic distribution and localization of immunocompetent cells in normal mouse endolymphatic sac. Acta Otolaryngol (Stockh) 1988; 106: 409–16.
   PubMed Web of Science ®Google Scholar
• Yeo SW, Gottschlich S, Harris JP, Keithley EM. Anti-gen diffusion from the perilymphatic space of the cochlea. Laryngoscope 1995; 105: 623–8.
   PubMedGoogle Scholar
• Chen MC, Harris JP, Keithley EM. Immunohisto-chemical analysis of proliferating cells in a sterile labyrinthitis animal model. Laryngoscope 1998; 108: 651–6.
   Google Scholar
• Ryan AF, Keithley EM, Harris JP. Autoimmune inner ear disorders. Curr Opin Neurol 2001; 14: 35–40.
   PubMed Web of Science ®Google Scholar
• Harris JP. Experimental autoimmune sensorineural hearing loss. Laryngoscope 1987; 97: 63–76.
   PubMed Web of Science ®Google Scholar
• Nair TS, Raphael Y, Dolan DF, et al. Monoclonal antibody induced hearing loss. Hear Res 1995; 83: 101–13.
   PubMed Web of Science ®Google Scholar
• Nair TS, Prieskorn DM, Miller JM, Dolan DF, Raphael Y, Carey TE. KHRI-3 monoclonal antibody-induced damage to the inner ear: antibody staining of nascent scars. Hear Res 1999; 129: 50–60.
   PubMed Web of Science ®Google Scholar
• Tomiyama S, Jinnouchi K, Ikezono T, Pawankar R, Yagi T. Experimental autoimmune labyrinthitis in-duced by cell-mediated immune reaction. Acta Otolar-yngol (Stockh) 1999; 119: 665–70.
   Google Scholar
• Bouman H, Klis SF, Meeuwsen F, de Groot JC, Smoorenburg GF, Veldman JE. Experimental autoim-mune inner ear disease: an electrocochleographic and histophysiologic study. Ann Otol Rhinol Laryngol 2000; 109: 457–66.
   Google Scholar
• Tomiyama S. Thl: mediator lymphocytes in experi-mental autoimmune labyrinthitis. Acta Otolaryngol 2001; 121: 673–8.
   PubMed Web of Science ®Google Scholar
• Cohen IR. Antigenic mimicry, clonal selection and autoimmunity. J Autoimmun 2001; 16: 337–40.
   PubMed Web of Science ®Google Scholar
• Harris JP, Sharp PA. Inner ear autoantibodies in pa-tients with rapidly progressive sensorineural hearing loss. Laryngoscope 1990; 100: 516–24.
   PubMed Web of Science ®Google Scholar
• Yoo TJ, Stuart JM, Kang AH, Townes AS, Tomoda K, Dixit S. Type II collagen autoimmunity in otoscle-rosis and Ménière's disease. Science 1982; 217: 1153–5.
   PubMed Web of Science ®Google Scholar
• Keithley EM, Chen MC, Linthicum F. Clinical diag-noses associated with histologic findings of temporal bone fibrotic tissue and new bone in the inner ear. Laryngoscope 1999; 108: 87–91.
   Google Scholar
• Darmstadt GL, Keithley EM, Harris JP. Effects of cyclophosphamide on the pathogenesis of cytomegalovirus-induced labyrinthitis. Ann Otol Rhinol Laryngol 1990; 99: 960–8.
   PubMedGoogle Scholar
• Harris JP, Moscicki RA, Hughes GB. Immunologic disorders of the inner ear. In: Hughes GB, Pensak ML, eds. Clinical otology, 2nd edn. New York: Thieme, 1996: 381–91.
   Google Scholar
• Sismanis A, Thompson T, Willis HE. Methotrexate therapy for autoimmune hearing loss: a preliminary report. Laryngoscope 1994; 104: 932–4.
   Google Scholar
• McCabe BF. Autoimmune inner ear disease. In: Bern-stein I, Ogra P, eds. Immunology of the ear. New York: Raven Press, 1987: 427–35.
   Google Scholar
• Luetje CM. Theoretical and practical implications for plasmapheresis in autoimmune inner ear disease. Laryngoscope 1989; 99: 1137–46.
   PubMedGoogle Scholar
• Cobo M, Haynes B. Early corneal findings in Cogan's syndrome. Ophthalmology 1984; 19: 903–7.
   Google Scholar
• Parnes LS, Sun AH, Freeman DJ. Corticosteroid pharmacokinetics in the inner ear fluids: an animal study followed by clinical application. Laryngoscope 1999; 109: 1–17.
   Google Scholar
• Yang GL, Song H, Keithley EM, Harris JP. Intratym-panic immunosuppressives for prevention of immune-mediated sensorineural hearing loss. Am J Otol 2000; 21: 499–504.
   PubMedGoogle Scholar
• Suzuki M, Harris JP. Expression of intercellular adhe-sion molecule-1 during inner ear inflammation. Ann Otol Rhinol Laryngol 1995; 104: 69–75.
   PubMed Web of Science ®Google Scholar
• Takasu T, Harris JP. Reduction of inner ear inflam-mation by treatment with anti-ICAM-1 antibody. Ann Otol Rhinol Laryngol 1997; 106: 1070–5.
   PubMedGoogle Scholar