Advanced search
Publication Cover
Acta Oto-Laryngologica Volume 118, 1998 - Issue 3
Submit an article Journal homepage
25
Views
6
CrossRef citations to date
0
Altmetric
Research Article

Non-radioactive Semiquantitative Testing for Expression Levels of Telomerase Activity in Head and Neck Squamous Cell Carcinomas may be Indicative for Biological Tumour Behaviour

DIETMAR THURNHER, BIRGIT KNERER, MICHAEL FORMANEK, JOHANNES KORNFEHL From the Department of Otorhinolaryngology, University of Vienna, Vienna, Austria
Pages 423-427 | Published online: 08 Jul 2009

References

  • Vokes EE, Weichselbaum RR, Lippman SM, Hong WK. Head and neck cancer. N Engl J Med 1993; 328: 184–94.
  • Shah JP. Patterns of cervical lymph node metastasis from squamous carcinomas of the upper aerodigestive tract. Am J Surg 1990; 160: 405–9.
  • McGuirt WF, Johnson JT, Myers EN, Rothfiel R, Wagner R. Floor of mouth carcinoma: the manage-ment of the clinically negative neck. Arch Otolaryngol Head Neck Surg 1995; 121: 278–82.
  • Eichler SA, Weber RS. Surgical management of cervi-cal lymph node metastases. Curr Opin Oncol 1996; 8: 215–20.
  • Sidransky D. Molecular genetics of head and neck cancer. Curr Opin Oncol 1995; 7: 229–33.
  • Brennan JA, Mao L, Hruban RH, et al. Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck. N Engl J Med 1995; 332: 429–35.
  • Shay JVV, Wright WE. Telomerase activity in human cancer. Curr Opin Oncol 1996; 8: 66–71.
  • Kim NW, Piatyszek MA, Prowse KR, et al. Specific association of human telomerase activity with immortal cells and cancer. Science 1994; 266: 2011–5.
  • Blackburn EH. Structure and function of telomeres. Nature 1991; 350: 569–73.
  • Feng J, Funk WD, Wang S, et al. The RNA compo-nent of the human telomerase. Science 1995; 269: 1236–41.
  • Zhu X, Kumar R, Mandal M, et al. Cell cycle-depen-dent modulation of telomerase activity in tumor cells. Proc Natl Acad Sci USA 1996; 93: 6091–5.
  • Allsop RC, Vaziri H, Patterson C, et al. Telomere length predicts replicative capacity of human fibrob-lasts. Proc Natl Acad Sci USA 1992; 89: 10114–8.
  • Wright WE, Piatyszek MA, Rainey WE, Byrd W, Shay JVV. Telomerase activity in human germline and embry-onic tissues and cells. Dev Genet 1996; 18: 173–9.
  • Bacchetti S, Counter CM. Telomeres and telomerase in human cancer (Review). Int J Oncol 1995; 7: 423–32.
  • Autexier C, Greider CW. Telomerase and cancer: revis-iting the telomere hyothesis. TIBS 1996; 21: 387–91.
  • Piatyszek MA, Kim NW, Weinrich SL, Hiyama E, Wright WE, Shay JVV. Detection of telomerase activity in human cells and tumors by a telomeric repeat am-plification protocol. Methods Cell Sci 1995; 17: 1–15.
  • Mutirangura A, Supiyaphun P, Trirekapan S, et al. Telomerase activity in oral leukoplakia and head and neck squamous cell carcinoma. Cancer Res 1996; 56: 3530–3.
  • Mao L, El-Naggar AK, Fan YH, et al. Telomerase activity in head and neck squamous cell carcinoma and adjacent tissue. Cancer Res 1996; 56: 5600.
  • Renan MJ. How many mutations are required for tumorigenesis? Implications from human cancer data. Mol Carcinogen 1993; 7: 139–46.
  • Axelrod N. Of telomeres and tumors. Nat Med 1996; 2: 158–9.
  • Taylor RS, Ramirez RD, Ogoshi M, Chaffins M, Pi-atyszek MA, Shay JW. Detection of telomerase activity in malignant and nonmalignant skin conditions. J In-vest Dermatol 1996; 106: 759–65.
  • Holt SE, Wright WE, Shay JVV. Regulation of telom-erase activity in immortal cell lines. Mol Cell Biol 1996; 16: 2932–9.
  • Hiyama E, Hiyama K, Yokoyama T, Matsuura Y, Piatyszek MA, Shay JVV. Correlating telomerase activ-ity levels with human neuroblastoma outcomes. Nat Med 1995; 1: 249–55.
  • Strahl C, Blackburn E. Effects of reverse transcriptase inhibitors on telomere length and telomerase activity in two immortalized human cell lines. Mol Cell Biol 1996; 16: 53–65.
  • Califano J, Ahrendt SA, Meininger G, Westra WH, Koch WM, Sidransky D. Detection of telomerase ac-tivity in oral rinses from head and neck squamous cell carcinoma patients. Cancer Res 1996; 56: 5720–2.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.