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Liquid Chromatography

High-Performance Liquid Chromatographic Method for the Simultaneous Determination of Four Flavonols in Food Supplements and Pharmaceutical Formulations

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Pages 1298-1314 | Received 28 Jul 2018, Accepted 10 Oct 2018, Published online: 24 Jan 2019

References

  • Agrawal, A. D. 2011. Pharmacological activities of flavonoids: A review. International Journal of Pharmaceutical Sciences and Nanotechnology 4 (2):1394–1398.
  • Ahuja, S. 2005. Overview: Handbook of pharmaceutical analysis by HPLC. Separation Science and Technology 6:1–17.
  • British Pharmacopoeia. 2011. accessed April 10, 2017. http://www.uspbpep.com/bp2008/data/6883.asp.
  • Carkeet, C., K. Grann, R. K. Randolpb, D. S. Venzon, and S. M. Izzy. 2013. Phytochemicals: health promotion and therapeutic potential. New York, USA: Taylor & Francis Group, LLC. accessed June 15, 2018. https://books.google.es/books/about/Phytochemicals.html?id=LEXSBQAAQBAJ&source=kp_cover&redir_esc=y.
  • (CCCMHPIE) China chamber of commerce for import and export of medicines and health products. 2015. Beijing, China. accessed June 25, 2018. http://www.cccmhpie.org.cn/.
  • Demirezer, L. Ö., A. Büyükkaya, E. Uçaktürk, A. Kuruüzüm-Uz, Z. Güvenalp, and E. Palaska. 2014. Adulteration determining of pharmaceutical forms of ginkgo biloba extracts from different international manufacturers. Records of Natural Products 8 (4):394–400.
  • Ding, S., E. Dudley, S. Plummer, J. Tang, R. P. Newton, and A. G. Brenton. 2006. Quantitative determination of major active components in ginkgo biloba dietary supplements by liquid chromatography/mass spectrometry. Rapid Communications in Mass Spectrometry 20 (18):2753–2760.
  • Dubber, M. J., and I. Kanfer. 2004. High-performance liquid chromatographic determination of selected flavonols in Ginko biloba solid oral dosage forms. Journal of Pharmacy and Pharmaceutical Science 7 (3):303–309.
  • European Medicines Agency. 2006. London, UK. accessed June 25, 2018. http://www.ich.org/products/guidelines/quality/quality-single/article/validation-of-analytical-procedures-text-and-methodology.html.
  • European pharmacopeia 6.0. 2008. accessed June 14, 2018. http://www.uspbpep.com/ep60/ginkgo%20leaf%201828e.pdf.
  • Graefe, E. U., J. Wittig, S. Mueller, A. K. Riethling, B. Uehleke, B. Drewelow, H. Pforte, G. Jacobasch, H. Derendorf, and M. Veit. 2001. Pharmacokinetics and bioavailability of quercetin glycosides in humans. The Journal of Clinical Pharmacology 41 (5):492–499.
  • Gray, D., K. LeVanseler, and M. Pan. 2005. Determination of flavonol aglycones in ginkgo biloba dietary supplement crude materials and finished products by high-performance liquid chromatography: single laboratory validation. Journal of AOAC International 88 (3):692–702.
  • Häkkinen, S. 2000. Flavonols and phenolic acids in berries and berry products. PhD thesis, Kuopio University.
  • Hendriks, M. M. W. B., J. H. deBoer, and A. K. Smilde. 1996. Robustness of analytical chemical methods and pharmaceutical technological products. 1–345. Vol.19. 1st ed. Amsterdam, Netherlands: Elsevier Science.
  • Hertog, M. G. L., P. C. H. Hollman, and D. P. Venema. 1992. Optimization of a quantitative HPLC determination of potentially anticarcinogenic flavonoids in vegetables and fruits. Journal of Agricultural and Food Chemistry 40 (9):1591–1598.
  • Joseph, S. M., and J. A. Palasota. 2001. The combined effects of pH and percent methanol on the HPLC separation of benzoic acid and phenol. Journal of Chemical Education 78 (10):1381–833.
  • Kromidas, S. 2006. HPLC made to measure: a practical handbook for optimization. Weinheim, Germany: Wiley-VCH. http://onlinelibrary.wiley.com/book/10.1002/9783527611973.
  • Kumar, S., and A. K. Pandey. 2013. Chemistry and biological activities of flavonoids: an overview. The Scientific World Journal 2013:1.
  • Luo, J. L., F. L. Lu, Y. C. Liu, Y. C. Shih, and C. F. LO. 2013. Fingerprint analysis of ginkgo biloba extract and ginkgo semen in preparations by LC-Q-TOF/MS. Journal of Food and Drug Analysis 21 (1):27–39.
  • Ma, Y. C., A. Mani, Y. Cai, J. Thomson, J. Ma, F. Peudru, S. Chen, M. Luo, J. Zhang, R. G. Chapman, and Z. T. Shi. 2016. An effective identification and quantification method for ginkgo biloba flavonol glycosides with targeted evaluation of adulterated products. Phytomedicine 23 (4):377–387.
  • Magiera, S., I. Baranowska, and A. Lautenszleger. 2015. UHPLC–UV method for the determination of flavonoids in dietary supplements and for evaluation of their antioxidant activities. Journal of Pharmaceutical and Biomedical Analysis 102:468–475.
  • Mesbah, M. K., S. I. Khalifa, A. El-Gindy, and K. A. Tawfik. 2005. HPLC determination of certain flavonoids and terpene lactones in selected ginkgo biloba L. phytopharmaceuticals. Farmaco (Societa Chimica Italiana : 1989) 60 (6–7):583–590.
  • Peng, B., R. Li, and W. Yan. 2009. Solubility of rutin in ethanol + water at (273.15 to 323.15) K. Journal of Chemical & Engineering Data 54 (4):1378–1381.
  • Quintin, J., and G. Lewin. 2005. Mild alkaline hydrolysis of some 7-O-flavone glycosides. Application to a novel access to rutinose heptaacetate. Tetrahedron Letters 46 (25):4341–4343.
  • Razmara, R. S., A. Daneshfar, and R. Sahraei. 2010. Solubility of quercetin in water + methanol and water + ethanol from (292.8 to 333.8) K. Journal of Chemical & Engineering Data 55 (9):3934–3936.
  • Reichardt, C. 2004. Solvents and solvents effects in organic chemistry. Weinheim, Germany: Wiley-VCH Verlag GmbH & Co.
  • Sati, P., and A. Pandey. 2016. Influence of age on ginkgo biloba phytochemicals in antimicrobial activity perspective. Journal of Graphic Era University 4 (2):57–65.
  • Šatínský, D., K. Jägerová, L. Havlíková, and P. Solich. 2013. A new and fast HPLC method for determination of rutin, troxerutin, diosmin and hesperidin in food supplements using fused-core column technology. Food Analytical Methods 6 (5):1353–1360.
  • Smallwood, I. M. 1996. Handbook of organic solvent properties. London, UK: A member of the Hodder Headline Group.
  • Snyder, L. R., J. J. Kirkland, and J. L. Glajch. 1997. Practical HPLC method development. 21–58. 2nd ed. Weinheim, Germany: John Wiley & Sons, Inc.
  • Snyder, L. R., J. J. Kirkland, and J. L. Glajch. 1997. Practical HPLC method development. 616–642. 2nd ed. Weinheim, Germany: John Wiley & Sons, Inc.
  • Stefova, M., T. Stafilov, and S. Kulevanova. 2003. HPLC analysis of flavonoids, encyclopedia of chromatography. Vol.8. New York: Marcel Dekker, Inc.
  • Tokuşoğlu, Ö., M. K. Ünal, and Z. Yıldırım. 2003. HPLC–UV and GC–MS characterization of the flavonol aglycons quercetin, kaempferol, and myricetin in tomato pastes and other tomato-based products. Acta Chromatographica 13:196–207.
  • Tu, X., S. Ma, Z. Gao, J. Wang, S. Huang, and W. Chen. 2017. One-step extraction and hydrolysis of flavonoid glycosides in rape bee pollen based on soxhlet-assisted matrix solid phase dispersion. Phytochemical Analysis 28 (6):505–511.
  • Tuszyńska, M. 2014. Validation of the analytical method for the determination of flavonoids in broccoli. Journal of Horticultural Research 22 (1):131–140.
  • U.S. Pharmacopeia USP32–NF27, USA-32. 2009. accessed June 14, 2018. http://www.uspbpep.com/search.asp.
  • Wang, J., L. L. Zhao, G. X. Sun, Y. Liang, F. A. Wu, Z. L. Chen, and S. M. Cui. 2011. A comparison of acidic and enzymatic hydrolysis of rutin. African Journal of Biotechnology 10 (8):1460–1466.
  • Water Corporation. 2008. Symmetry Family of HPLC columns Care and Use Manual. http://www.waters.com/waters/support.htm?cid=513219&lid=10008732&locale=en_GB (accessed June 15, 2018).
  • World health organization (WHO) 2007. WHO guidelines for assessing quality of herbal medicines with reference to contaminants and residues. http://www.who.int/iris/handle/10665/43510 (accessed June 14, 2018).
  • Yao, X., Zhou, G. S. Y. P. Tang, Y. F. Qian, H. L. Guan, H. Pang, S. Zhu, X. Mo, S. L. Su, C. Jin, Y., et al. 2013. Simultaneous quantification of flavonol glycosides, terpene lactones, biflavones, proanthocyanidins, and ginkgolic acids in ginkgo biloba leaves from fruit cultivars by ultrahigh-performance liquid chromatography coupled with triple quadrupole mass spectrometry. BioMed Research International 2013:1–591.
  • Zu, Y., C. Li, Y. Fu, and C. Zhao. 2006. Simultaneous determination of catechin, rutin, quercetin kaempferol and isorhamnetin in the extract of sea buckthorn (Hippophae rhamnoides L.) leaves by RP-HPLC with DAD. Journal of Pharmaceutical and Biomedical Analysis 41 (3):714–719.

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