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Original Articles

Contribution on the Mode of Action of Germanin (Bayer 205)

Pages 13-19 | Received 26 Jul 1938, Published online: 22 Mar 2016

REFERENCES

  • Dangerfield, W. G., Gaunt, W. E., and Wormall, A. (1938). Studies on Bayer 205 (germanin) and antrypol. I: The determination of small amounts of Bayer 205 (and antrypol). II: The persistence of Bayer 205 in the blood stream after injection into animals. Biochem. Jl., 32, 59.
  • Hawking, F. (1937). Studies on chemotherapeutic action. I: The absorption of arsenical compounds and tartar emetic by normal and resistant trypanosomes and its relation to drug-resistance. Jl. Pharmacol., 59, 123.
  • Hawking, F. (1938). Analysis of the trypanocidal action of trivalent arsenicals and acriflavine. Ann. Trop. Med. & Parasitol., 32, 313.
  • Issekutz, B. von (1933). Beiträge zur Wirkung des Germanins. II. Arch. Exper. Path. u. Pharmak., 173, 499.
  • JancsÓ, N. von, and Jancsó, H. von (1934). Mikrobiologische Grundlagen der chemotherapeutischen Wirkung. I: Wirkungsmechanismus des Germanins (Bayer 205) bei Trypanosomen. Zentralbl. f. Bakt., Orig., 132, 257.
  • JancsÓ, N. von, and Jancsó, H. von (1935). The rôle of the natural defence forces in the evolution of the drug-resistance of trypanosomes. II: The rapid production of germanin-fast T. brucei strains in animals with paralyzed defence. Ann. Trop. Med. & Parasitol., 29, 95.
  • Nauck, E. (1925). Untersuchungen über die Wirkung des Trypanosomenheilmittels ‘Bayer 205’. Arch. f. Schiffs- u. Trop.-Hyg., 29, 1.
  • Reiner, L., and KÖveskuty, J. (1927). Ueber den Wirkungsmechanismus von Bayer 205. Deutsch. Med. Woch., 53, 1988.
  • Yorke, W., and Murgatroyd, F. (1930). Studies in chemotherapy. III: The action in vitro of certain arsenical and antimonial compounds on T. rhodesiense and on atoxyl- and acriflavine- resistant strains of this parasite. Ann. Trop. Med. & Parasitol., 24, 449.
  • Yorke, W., and Murgatroyd, F. and Hawking, F. (1931a). Studies in chemotherapy. IV: The action in vivo of certain arsenical and antimonial compounds and of Bayer 205 on T. rhodesiense and on atoxyl- and acriflavine-resistant strains of this parasite. Ibid., 25, 313.
  • Yorke, W., and Murgatroyd, F. and Hawking, F. (1931b). Studies in chemotherapy. VI: The production of resistant strains by exposure of trypanosomes to reduced tryparsamide in vitro. Ibid., 25, 521.
  • Yorke, W., and Murgatroyd, F. and Hawking, F. (1932). Studies in chemotherapy. VIII: Comparison of strains of T. rhodesiense made resistant to various arsenicals and antimonials, to Bayer 205, and to acriflavine, respectively. Ibid., 26, 577.

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