Advanced search
Publication Cover
Annals of Tropical Medicine & Parasitology Volume 82, 1988 - Issue 4
Journal homepage
5
Views
2
CrossRef citations to date
0
Altmetric
Original Articles

Sensitivity of Plasmodium falciparum to mefloquine—sulphadoxine—pyrimethamine (Fansimef®) in vivo and to mefloquine alone in vitro in Nigeria

L. A. SalakoDepartment of Pharmacology and Therapeutics, University of Ibadan, Ibadan, Nigeria
,
A. Fadeke AderounmuDepartment of Pharmacology and Therapeutics, University of Ibadan, Ibadan, Nigeria
,
J. O. LaoyeDepartment of Pharmacology and Therapeutics, University of Ibadan, Ibadan, Nigeria
,
J. Modupe MakindeDepartment of Pharmacology and Therapeutics, University of Ibadan, Ibadan, Nigeria
&
R. Aina AdioDepartment of Pharmacology and Therapeutics, University of Ibadan, Ibadan, Nigeria
Pages 325-330 | Received 23 Jan 1987, Published online: 15 Nov 2016

REFERENCES

  • Aderounmu, A. F., Salako, L. A. & Walker, O. (1981). Chloroquine sensitivity of P. falciparum in Ibadan, Nigeria. II. Correlation of in vivo with in vitro sensitivity. Transactions of the Royal Society of Tropical Medicine and Hygiene, 75, 637–640.
  • Botero, D., Restrepo, M. & Montova, A. (1985). Prospective double-blind trial of two different doses of mefloquine plus pyrimethamine—sulphadoxine compared with pyrimethamine—sulphadoxine alone in the treatment of falciparum malaria. Bulletin of the World Health Organization, 63, 731–737.
  • Hackett, L. W. (1944). Spleen measurement in malaria. Journal of the National Malaria Society, 3, 121–133.
  • Harinasuta, T., Bunnag, D., Lasserre, R., Leimer, R. & Vinijanont, S. (1985). Trials of mefloquine in vivax and of mefloquine plus Fansidar in falciparum malaria. Lancet, 1, 885–888.
  • Kofi Ekue, J. M., Ullrich, A. M., Rwabwogo-Atenyi, J. & Sheth, U. K. (1983). A double-blind comparative clinical trial of mefloquine and chloroquine in symptomatic falciparum malaria. Bulletin of the World Health Organization, 61, 713–718.
  • Le Bras, J., Hatin, I., Bouree, P., Coco-Cianci, O., Garin, J.-P., Rey, M., Charmot, G. & Roue, R. (1986). Chloroquine-resistant falciparum malaria in Benin. Lancet, 2, 1043–1044.
  • Merkli, B., Richie, R. & Peters, W. (1980). The inhibitory effect of a drug combination on the development of mefloquine resistance in P. berghei. Annals of Tropical Medicine and Parasitology, 74, 1–9.
  • Myint, L., Htut, Y. & Oo, M. (1985). The in vivo and in vitro sensitivity of Plasmodium falciparum to quinine. Southeast Asian Journal of Tropical Medicine and Public Health, 16, 214–218.
  • Olatunde, A., Salako, L. A. & Walker, O. (1981). In vivo sensitivity of P. falciparum to sulphadoxine—pyrimethamine combination in Ibadan, Nigeria. Transactions of the Royal Society of Tropical Medicine and Hygiene, 75, 848–852.
  • Peters, W. & Robinson, B. L. (1984). Further studies on the retardation of during resistance by the use of a triple combination of mefloquine, pyrimethamine and sulphadoxine on mice infected with P. berghei and P. berghei N.S. Annals of Tropical Medicine and Parasitology, 78, 459–466.
  • Rieckmann, K. H., Campbell, G. H., Sax, L. J. & Mrema, J. E. (1978). Drug sensitivity of P. falciparum. An in vitro microtechnique. Lancet, 1, 22–23.
  • Sansonetti, P. J., Le Bras, C., Verdier, F., Charmot, G., Dupout, B. & Lapresle, C. (1985). Chloroquine-resistant P. falciparum in Cameroon. Lancet, 1, 1154–1155.
  • Tin, F., Hlaing, N., Tun, T., Win, S. & Lasserre, R. (1985). Falciparum malaria treated with a fixed combination of mefloquine, sulphadoxine and pyrimethamine: a field study in adults in Burma. Bulletin of the World Health Organization, 63, 727–730.
  • Walker, O., Salako, L. A., Obih, P. O., Bademosi, K. & Sodeinde, O. (1984). The sensitivity of P. falciparum to chloroquine and amodiaquine in Ibadan, Nigeria. Transactions of the Royal Society of Tropical Medicine and Hygiene, 78, 782–784.
  • World Health Organization (1973). Chemotherapy of Malaria and Resistance to antimalarials. Geneva: Technical Report Series No. 529.
  • World Health Organization (1982). Instructions for Use of the Micro Test Kit for the Assessment of the Response of Plasmodium falciparum to chloroquine and mefloquine in vitro, Geneva: MAP–82.1.
  • World Health Organization (1984). Advances in Malaria Chemotherapy. Geneva: Technical Report Series No. 711.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.