REFERENCES
- Ballou, R., Rothbard, J., Wirtz, R. A., Gordon, D. M., Williams, J., Schneider, I., Hollingdale, M. R., Beaudoin, R. L., Maloy, V., Miller, H. & Hockmeyer, W. T. (1985). Immunogenicity of synthetic peptides from the circumsporozoite protein of Plasmodium falciparum. Science, 228, 996–999.
- Bilsborough, J., Carlisle, M. & Good, M. F. (1993). Identification of Caucasian CD4 T cell epitopes on the circumsporozoite protein of Plasmodium vivax. T cell memory. Journal of Immunology, 151, 890–899.
- Celada, F. & Sercarz, E. (1988). Preferential pairing of T-B specificities in the same antigen: the concept of directional help. Vaccine, 6, 94–98.
- Charoenvit, Y., Collins, W. E., Jones, T. R., Millet, P., Yuan, L., Campbell, G. H., Beaudoin, R. L., Broderson, J. R & Hoffman, S. L. (1991). Inability of malaria vaccine to induce antibodies to a protective epitope within its sequence. Science, 251, 668–671.
- Cunha-Neto, E. (1999). MHC restricted antigen presentation and recognition: constraints on gene, recombinant and peptide vaccines in humans. Brazilian Journal of Medical and Biological Research, 32, 199–203.
- Del Giudice, G., Cheng, Q., Mazier, D., Meuwissen, J. H., Grau, G. E., Corradin, G., Pessi, A., Verdini, A. S. & Lambert, P. H. (1989). Primary and secondary responses to (NANP) peptides by Plasmodium falciparum sporozoites in various strains of mice. Scandinavian Journal of Immunology, 29, 555–562.
- Del Giudice, G., Tougne, C., Louis, J. A., Lambert, P. H., Bianchi, E., Bonelli, F., Chiappinelli, L. & Pessi, A. (1990). A multiple antigen peptide from the repetitive sequence of the Plasmodium malariae circumsporozoite protein induces a specific antibody response in mice of various H-2 haplotypes. European Journal of Immunology, 20, 1619–1622.
- Gordon, D. M., Cosgriff, T. M., Schneider, I., Wasserman, G. F., Majarian, W. R., Hollingdale, M. R. & Chulay, J. D. (1990). Safety and immunogenicity of a Plasmodium vivax sporozoite vaccine. American Journal of Tropical Medicine and Hygiene, 42, 527–531.
- Grau, G. E., Bieler, G., Pointaire, P., de Kossodo, S., Tacchini-Cotier, F., Vassalli, P., Piguet, P. F. & Lambert, P. H. (1990). Significance of cytokine production and adhesion molecules in malarial immunopathology. Immunology Letters, 25, 189–194.
- Herrera, S., Herrera, M. A., Corredor, A., Rosero, F., Clavijo, C. & Guerrero, R. (1992). Failure of a synthetic vaccine to protect Aotus lemurinus against asexual blood stages of Plasmodium falciparum. American Journal of Tropical Medicine and Hygiene, 47, 682–690.
- Kironde, F. A., Kumar, A., Nayak, A. R. & Kraikov, J. L. (1991). Antibody recognition and isoelectrofocussing of antigens of the malaria parasite Plasmodium yoelii. Infection and Immunity, 59, 3909–3916.
- Krzych, U., Schwenk, R., Guebre-Xabier, M., Sun, P., Palmer, D., White, K. & Chalom, I. (2000). The role of intrahepatic lymphocytes in mediating protective immunity induced by attenuated Plasmodium berghei sporozoites. Immunology Review, 174, 123–134.
- Kumaratilake, L. M. & Ferrante, A. (1992). IL-4 inhibits macrophage-mediated killing of Plasmodium falciparum in vitro. A possible parasite-immune evasion mechanism. Journal of Immunology, 149, 194–199.
- Langhorne, J. (1989). The role of CD4+ T cells in the murine response to Plasmodium chabaudi. Parasitology Today, 5, 362–364.
- Leclerc, C., Przewlocki, G., Schultze, M. P. & Chedid, L. (1987). A synthetic vaccine constructed by copolymerization of B and T cell determinants. Journal of Immunology, 17, 269–273.
- Mazier, D., Renia, L., Nussler, A., Pied, S., Marussig, M., Goma, J., Grillot, D., Miltgen, F., Drapier, J. C., Corradin, G., del Guidice, G. & Grau, G. E. (1990). Hepatic phase of malaria is the target of cellular mechanisms induced by the previous and the subsequent stages. A crucial role for liver nonparenchymal cells. Immunology Letters, 25, 65–70.
- Migot, F., Millet, P., Chougnet, C., Lepers, J. P. & Deloron, P. (1993). Humoral and cellular immune responses to the circumsporozoite protein of Plasmodium vivax in Madagascar. American Journal of Tropical Medicine and Hygiene, 48, 524–529.
- Mossman, T. R. & Coffman, R. L. (1989). Heterogeneity of cytokine secretion patterns and functions of helper T cells. Advances in Immunology, 46, 111–147.
- Nardin, E. H. (1990). T cell responses in a sporozoite-immunized human volunteer and a chimpanzee. Immunology Letters, 25, 43–48.
- Nardin, E., Clavijo, P., Mons, B., van Belkum, A., Ponnudurai, T. & Nussenzweig, R. S. (1991). T cell epitopes of the circumsporozoite protein of Plasmodium vivax recognition by lymphocytes of a sporozoite-immunized Chimpanzee. Journal of Immunology, 146, 1674–1678.
- Nussenzweig, V. & Nussenzweig, R. S. (1989). Rationale for the development of an engineered sporozoite malaria vaccine. Advances in Immunology, 45, 283–334.
- Perlmann, H., Kumar, S., Vinetz, J. M., Kullberg, M., Miller, L. H. & Perlmann, P. (1995). Cellular mechanisms in the immune response to malaria in Plasmodium vinckei-infected mice. Infection and Immunity, 63, 3987–3993.
- Procell, P., Bathurst, I. C, Lowell, G., Ruebush II, T. K., Skinner, J. C., Hightower, A. W. & Collins, W. E. (1991). Cellular proliferative responses in squirrel monkeys immunized with recombinant and synthetic Plasmodium vivax circumsporozoite peptides. American Journal of Tropical Medicine and Hygiene, 44, 632–639.
- Rodrigues, M. M., Paiva, A. C. M., Dutra, A. P., Yoshida, N. & Nakaie, C. (1991). Identification of epitopes within the circumsporozoite protein of Plasmodium vivax recognized by murine T lymphocytes. Experimental Parasitology, 72, 271–277.
- Romero, P., Heimer, E. P., Herrera, S., Felix, A., Nussenzweig, R. S. & Zavala, F. (1987). Antigenic analysis of the repeat domain of the circumsporozoite protein of Plasmodium vivax. Journal of Immunology, 139, 1679–1682.
- Shahi, S., Kumar, P., Kamboj, K. K. & Rao, D. N. (1997). Immune response against the non-repeat region (293–310) of the circumsporozoite protein of Plasmodium vivax. Southeast Asian Journal of Tropical Medicine and Public Health, 28, 748–756.
- Sinigaglia, F., Guttinger, M., Kilgus, J., Doran, D. M., Matile, H., Etlinger, H. M., Trzeciak, A., Gillessen, D. & Pink, J. R. L. (1988). A malaria T-epitope recognized in association with most mouse and human MHC class II molecules. Nature, 336, 778–780.
- Tam, J. P., Clavijo, P., Lu, Y. A., Nussenzweig, V., Nussenzweig, R. & Zavala, F. (1990). Incorporation of T and B epitopes of the circumsporozoite protein in a chemically defined synthetic vaccine against malaria. Journal of Experimental Medicine, 171, 299–306.
- Taylor-Robinson, A. W. & Looker, M. (1998). Sensitivity of malaria parasites to nitric oxide at low oxygen tensions. Lancet, 351, 1630.
- Thomas, B. E., Manocha, M., Haq, W., Adak, T., Pillai, C. R. & Rao, D. N. (2001). Modulation of the humoral response to repeat and non-repeat sequences of the circumsporozoite protein of Plasmodium vivax using novel adjuvant and delivery systems. Annals of Tropical Medicine and Parasitology, 95, 451–472.
- Udhayakumar, V., Saekhou, A. E., Sunan, F., Danny, J., Robert, M. W. & Lal, A. A. (1998). Immunogenicity of Plasmodium falciparum and Plasmodium vivax circumsporozoite protein repeat multiple antigen constructs (MAC). Vaccine, 16, 982–988.
- Verma, J. N., Wassef, N. M., Wirtz, R. A., Atkinson, C. T., Aikawa, M., Loomis, L. D. & Alving, C. R. (1991). Phagocytosis of liposomes by macrophages: intracellular fate of liposomal malaria antigen. Biochimica et Biophysica Acta, 1066, 229–238.
- Wang, R., Charoenvit, Y., Corradin, G., Porrozzi, R., Hunter, R. L., Glenn, G., Alving, C. R., Church, P. & Hoffman, S. L. (1995). Induction of protective polyclonal antibodies by immunization with Plasmodium yoelii circumsporozoite protein multiple antigen peptide vaccine. Journal of Immunology, 155, 1637–1641.
- Yang, C., Collins, W. E., Xiao, L., Saekhou, A. M., Reed, R. C., Nelson, C. O., Hunter, R. L., Jue, D. L., Fang, S., Wohlhueter, R. M., Udhayakumar, V. & Lal, A. A. (1997). Induction of protective antibodies in Saimiri monkeys by immunization with a multiple antigen construct (MAC) containing the Plasmodium vivax circumsporozoite protein repeat region and a universal T helper epitope of tetanus toxin. Vaccine, 15, 377–386.
- Zevering, Y., Khamboonruang, C., Rungruengthanakit, K., Tungviboonchai, L., Ruengpipattanapan, J., Bathurst, I., Barr, P. & Good, M. F. (1994). Life-spans of human T-cell responses to determinants from the circumsporozoite proteins of Plasmodium falciparum and Plasmodium vivax. Proceedings of National Academy of Sciences of the United States of America, 91, 6118–6122.