155
Views
5
CrossRef citations to date
0
Altmetric
Original Articles

Nicotinamide nucleotide transhydrogenase expression analysis in multiple sclerosis patients

, , ORCID Icon, &
Pages 1256-1260 | Received 07 Dec 2018, Accepted 10 Aug 2019, Published online: 02 Sep 2019

References

  • Ripoll VM, Meadows NA, Bangert M, et al. Nicotinamide nucleotide transhydrogenase (NNT) acts as a novel modulator of macrophage inflammatory responses. FASEB J. 2012;26(8):3550–3562.
  • Van Der Valk P, De Groot CJ. Staging of multiple sclerosis (MS) lesions: pathology of the time frame of MS. Neuropathol Appl Neurobiol. 2000;26(1):2–10.
  • Parker N, Vidal-Puig AJ, Azzu V, et al. Dysregulation of glucose homeostasis in nicotinamide nucleotide transhydrogenase knockout mice is independent of uncoupling protein 2. Biochim Biophys Acta. 2009;1787(12):1451–1457.
  • Arsenijevic D, Onuma H, Pecqueur C, et al. Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production. Nat Genet. 2000;26(4):435–439.
  • Huang Y, Shi J, Xu Y. Long non-coding RNA NNT-AS1 contributes to cell proliferation, metastasis and apoptosis in human ovarian cancer. Oncol Lett. 2018;15(6):9264–9270.
  • Wight M, Werner A. The functions of natural antisense transcripts. Essays Biochem.. 2013;54:91–101.
  • Nicot A. Gender and sex hormones in multiple sclerosis pathology and therapy. Front Biosci (Landmark Ed). 2009;14:4477–4515.
  • Guillemin F, Baumann C, Epstein J, et al. Older age at multiple sclerosis onset is an independent factor of poor prognosis: a population-based cohort study. Neuroepidemiology. 2017;48(3-4):179–187.
  • Voskuhl RR, Sawalha AH, Itoh Y. Sex chromosome contributions to sex differences in multiple sclerosis susceptibility and progression. Mult Scler. 2018;24(1):22–31.
  • Wilcoxen SC, Kirkman E, Dowdell KC, et al. Gender-dependent IL-12 secretion by APC is regulated by IL-10. J Immunol. 2000;164(12):6237–6243.
  • Chao TC, VAN Alten PJ, Greager JA, et al. Steroid sex hormones regulate the release of tumor necrosis factor by macrophages. Cell Immunol. 1995;160(1):43–49.
  • Numakawa Y, Matsumoto T, Yokomaku D, et al. 17beta-estradiol protects cortical neurons against oxidative stress-induced cell death through reduction in the activity of mitogen-activated protein kinase and in the accumulation of intracellular calcium. Endocrinology. 2007;148(2):627–637.
  • Rousset S, Emre Y, Join-Lambert O, et al. The uncoupling protein 2 modulates the cytokine balance in innate immunity. Cytokine. 2006;35(3–4):135–142.
  • Hoek JB, Rydstrom J. Physiological roles of nicotinamide nucleotide transhydrogenase. Biochem J. 1988;254(1):1–10.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.