224
Views
12
CrossRef citations to date
0
Altmetric
Original Articles

Fabrication and Characterization of Gelatin/Chitosan Microspheres for Drug Release

, , , , , & show all
Pages 777-785 | Received 13 Feb 2011, Accepted 29 Apr 2011, Published online: 09 Mar 2012

References

  • Madihally , S. V. and Matthew , H. W. 1999 . Porous chitosan scaffolds for tissue engineering . Biomaterials , 20 : 1133 – 1142 .
  • Khor , E. and Lim , L. Y. 2003 . Implantable applications of chitin and chitosan . Biomaterials , 24 : 2339 – 2349 .
  • Freiberg , S. and Zhu , X. X. 2004 . Polymer microspheres for controlled drug release . Int. J. Pharm. , 282 : 1 – 18 .
  • Xia , W. , Liu , W. , Cui , L. , Liu , Y. , Zhong , W. and Liu , D. 2004 . Tissue engineering of cartilage with the use of chitosan-gelatin complex scaffolds . J. Biomed. Mater. Res. , 71B : 373 – 380 .
  • Zhao , F. , Yin , Y. , Lu , W. W. , Leong , J. C. , Zhang , W. , Zhang , J. , Zhang , M. and Yao , K. 2002 . Preparation and histological evaluation of biomimetic three-dimensional hydroxyapatite/chitosangelatin network composite scaffolds . Biomaterials , 23 : 3227 – 3234 .
  • Wang , X. H. , Li , D. P. , Wang , W. J. , Feng , Q. L. , Cui , F. Z. and Xu , Y. X. 2004 . Crosslinked collagen/chitosan matrix for artificial livers . Biomaterials , 24 : 3213 – 3220 .
  • Mao , J. , Zhao , L. , Yao , K. D. , Shang , Q. , Yang , G. and Cao , Y. 2003 . Study of novel chitosan-gelatin artificial skin in vitro . J. Biomed. Mater. Res. , 64A : 301 – 308 .
  • Adhirajan , N. , Shanmugasundaram , N. and Babu , M. 2007 . Gelatin microspheres cross-linked with EDC as a drug delivery system for doxycyline: development and characterization . J. Microencapsul. , 24 : 647 – 659 .
  • Ugwoke , M. I. and Kinget , R. 1998 . Influence of processing variables on the properties of gelatin microspheres prepared by the emulsification solvent extraction technique . J. Microencapsul. , 15 : 273 – 281 .
  • Brime , B. , Ballesteros , M. P. and Frutos , P. 2000 . Preparation and in vitro characterization of gelatin microspheres containing Levodopa for nasal administration . J. Microencapsul. , 17 : 777 – 784 .
  • Rathna , G. V.N. 2008 . Gelatin hydrogels: enhanced biocompatibility, drug release and cell viability . J. Mater. Sci: Mater. Med. , 19 : 2351 – 2358 .
  • Drury , J. L. and Mooney , D. J. 2003 . Hydrogels for tissue engineering: scaffold design variables and applications . Biomaterials , 24 : 4337 – 4351 .
  • Tabata , Y. , Uno , K. , Ikada , Y. and Muramatsus , S. 1989 . Synthesis of gelatin microspheres containing interferon . Pharm. Res. , 6 : 422 – 427 .
  • Lim , L. Y. , Wan , L. S. and Thai , P. Y. 1997 . Chitosan microspheres prepared by emulsification and ionotropic gelation . Drug Dev. Ind. Pharm. , 23 : 981 – 985 .
  • Huang , Y. , Yeh , M. and Chiang , C. 2002 . Formulation factors in preparing BTM–chitosan microspheres by spray drying method . Int. J. Pharm. , 24 : 239 – 242 .
  • Patel , M. , Jain , S. K. , Yadav , A. K. , Gogna , D. and Agrawal , G. P. 2006 . Preparation and characterization of oxybenzone-loaded gelatin microspheres for enhancement of sunscreening efficacy . Drug Deliv. , 13 : 323 – 330 .
  • Esposito , E. , Cortesi , R. and Nastruzzi , C. 1996 . Gelatin microspheres: influence of preparation parameters and thermal treatment on chemicophysical and biopharmaceutical properties . Biomaterials , 17 : 2009 – 2020 .
  • Shu , X. Z. and Zhu , K. J. 2001 . Chitosan/gelatin microspheres prepared by modified emulsification and ionotropic gelation . J. Microencapsul. , 18 : 237 – 245 .
  • Sun , R. , Shi , J. , Guo , Y. and Chen , L. 2009 . Studies on the particle size control of gelatin microspheres . Front. Chem. China , 4 : 222 – 228 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.