203
Views
8
CrossRef citations to date
0
Altmetric
Original Articles

Fabrication and Properties of Gelatin/Chitosan Microspheres Loaded with 5-Fluorouracil

, , , , , , , & show all
Pages 973-983 | Received 22 May 2012, Accepted 30 Oct 2012, Published online: 04 Apr 2013

References

  • Chen , G. G. , Zhou , B. Q. , Li , X. M. and Wei , P. 2006 . Preparation and release characteristics of 5-fluorouracil loaded PLGA-nanoparticles . J. Chin. Pharm. Univ , 37 : 423
  • Lu , Y. and Chen , S. C. 2004 . Micro and nano-fabrication of biodegradable polymers for drug delivery . Adv. Drug Deliv. Rev. , 56 : 1621
  • Ahmed , A. , Bonner , C. and Desai , T. A. 2002 . Bioadhesive microdevices with multiple reservoirs: a new platform for oral drug delivery . J. Control. Release , 81 : 291
  • Chiang , C.-H. , Tung , S.-M. , Lu , D.-W. and Yeh , M.-K. 2001 . In vitro and in vivo evaluation of an ocular delivery system of 5-fluorouracil microspheres . J. Ocul. Pharmacol. Ther. , 17 : 545
  • Lamprecht , A. , Yamamoto , H. , Takeuchi , H. and Kawashima , Y. 2003 . Microsphere design for the colonic delivery of 5-fluorouracil . J. Control. Release , 90 : 313
  • Freiberg , S. and Zhu , X. X. 2004 . Polymer microspheres for controlled drug release . Int. J. Pharm , 282 : 1
  • Brime , B. , Ballesteros , M. P. and Frutos , P. 2000 . Preparation and in vitro characterization of gelatin microspheres containing Levodopa for nasal administration . J. Microencapsul. , 17 : 777
  • Peng , Z. Y. , Peng , Z. P. and Shen , Y. Q. 2011 . Control of size and morphology of gelatin microspheres . J. Macromol. Sci., Part B, Phys , 50 : 12
  • Yoshino , T. , Machida , Y. , Onishi , H. and Nagai , T. 2003 . Preparation and characterization of chitosan microspheres containing doxifluridine . Drug Dev. Ind. Pharm , 29 : 417
  • Ohta , S. , Nitta , N. , Takahashi , M. , Murata , K. and Tabata , Y. 2007 . Degradable gelatin microspheres as an embolic agent: an experimental study in a rabbit renal model . Korean J. Radiol. , 8 : 418
  • Kumbar , S. G. , Kulkarni , A. R. and Aminabhavi , T. M. 2002 . Crosslinked chitosan microspheres for encapsulation of diclofenac sodium: effect of crosslinking agent . J. Microencapsul , 19 : 173
  • Ko , J. A. , Park , H. J. , Hwang , S. J. , Park , J. B. and Lee , J. S. 2002 . Preparation and characterization of chitosan microparticles intended for controlled drug delivery . Int. J. Pharm , 249 : 165
  • Lee , E. , Lee , J. , Lee , I. H. , Yu , M. , Kim , H. , Chae , S. Y. and Jon , S. 2008 . Conjugated chitosan as a novel platform for oral delivery of paclitaxel . J. Med. Chem , 51 : 6442
  • Rai , G. , Jain , S. K. , Agrawal , S. , Pancholi , S. S. and Agrawal , G. P. 2005 . Chitosan hydrochloride based microspheres of albendazole for colonic drug delivery . Pharmazie , 60 : 131
  • Yang , Y. W. , Lee , J. S. , Kim , I. , Jung , Y. J. and Kim , Y. M. 2006 . Synthesis and properties of N-nicotinoyl-2-(5-fluorouracil-1-yl)-D,L-glycine ester as a prodrug of 5-fluorouracil for rectal administration . Eur. J. Pharm. Biopharm , 66 : 260
  • Jean , L. G. , Diana , N. , Brian , P. M. , Vivian , K. and Francois , J. G. 1999 . Sequence-dependent antagonism between fluorouracil and paclitaxel in human breast cancer cells . Biochem. Pharmacol , 58 : 477
  • Warr , J. R. , Bamford , A. and Quinn , D. M. 2002 . The preferential induction of apoptosis in multidrug-resistant KB cells by 5-fluorouracil . Cancer Lett , 175 : 39
  • Yoneda , K. , Yamamoto , T. and Osaki , T. 1998 . p53- and p21-independent apoptosis of squamous cell carcinoma cells induced by 5-fluorouracil and radiation . Oral Oncol. , 34 : 529
  • Mizutania , Y. , Nakanishia , H. , Yoshidab , O. , Fukushimac , M. , Bonavidad , B. and Mikia , T. 2002 . Potentiation of the sensitivity of renal cell carcinoma cells to TRAIL-mediated apoptosis by subtoxic concentrations of 5-fluorouracil . Eur. J. Cancer , 38 : 167
  • Denkbas , E. D. , Seyyal , M. and Piskins , E. 1999 . 5-Fluorouracil loaded Chitosan microspheres for chemo embolization . J. Microencapsul , 16 : 741
  • Sekhar , E. C. , Rao , K. K.S.V. and Raju , R. R. 2011 . Chitosan/guargum-g-acrylamide semi IPN microspheres for controlled release studies of 5-Fluorouracil . J. Appl. Pharma. Sci , 1 : 199
  • Denkbas , E. D. , Seyyal , M. and Piskins , E. 1999 . 5-Fluorouracil loaded Chitosan microspheres for chemo embolization . J. Microencapsul , 16 : 741

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.