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Beta‐lactam resistance in the Gram negatives: increasing complexity of conditional, composite and multiply resistant phenotypes

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Pages 498-506 | Received 15 Sep 2006, Accepted 22 Sep 2006, Published online: 06 Jul 2009

References

  • Weinstein R. A. Nosocomial infection update. Emerg Infect Dis 1998; 4: 416–20
  • Wenzel R. P., Pfaller M. A. Feasible and desirable targets for reducing the costs of hospital infections. J Hosp Infect 1991; 18: 94
  • Paladino J. A. Economic justification of antimicrobial management programs: implications of antimicrobial resistance. Am J Health Syst Pharm 2000; 57: S10–2
  • Playford E. G., Craig J. C., Simpson J., Iredell J. R. Carbapenem Resistant Acinetobacter baumannii (CR‐AB) in ICU Patients: Attributable Mortality and Length of Stay, American Society for Microbiology, 43rd Interscience Conference on Antimicriobial Agents and Chemotherapy, September 14–17, 2003, Chicago, USA
  • Rello J., Rue M., Jubert P., et al. Survival in patients with nosocomial pneumonia: impact of the severity of illness and the etiologic agent. Crit Care Med 1997; 25: 1862–7
  • French G. L., Cheng A. F. Measurement of the costs of hospital infection by prevalence surveys. J Hosp Infect 1991; 18: 65–72
  • Phelps C. E. Bug/drug resistance. Sometimes less is more. Med Care 1989; 27: 194–203
  • Smith R., Meixler S., Simberkoff M. Excess mortality in critically ill patients with nosocomial bloodstream infections. Chest 1991; 100: 164–7
  • Crowcroft N. S., Catchpole M. Mortality from methicillin resistant Staphylococcus aureus in England and Wales: analysis of death certificates. BMJ 2002; 325: 1390–1
  • Alvarez‐Lerma F. Modification of empiric antibiotic treatment in patients with pneumonia acquired in the intensive care unit. ICU‐Acquired Pneumonia Study Group. Intensive Care Med 1996; 22: 387–94
  • Iregui M., Ward S., Sherman G., Fraser V. J., Kollef M. H. Clinical importance of delays in the initiation of appropriate antibiotic treatment for ventilator‐associated pneumonia. Chest 2002; 122: 262–8
  • Luna C., Vujacich P., Niederman M., et al. Impact of BAL data on the therapy and outcome of ventilator‐associated pneumonia. Chest 1997; 111: 676–85
  • Ibrahim E. H., Sherman G., Ward S., Fraser V. J., Kollef M. H. The influence of inadequate antimicrobial treatment of bloodstream infections on patient outcomes in the ICU setting. Chest 2000; 118: 146–55
  • Boots R. J., Lipman J., Bellomo R., Stephens D., Heller R. F. Disease risk and mortality prediction in intensive care patients with pneumonia. Australian and New Zealand practice in intensive care (ANZPIC II). Anaesth Intensive Care 2005; 33: 101–11
  • Villers D., Espaze E., Coste‐Burel M., et al. Nosocomial Acinetobacter baumannii infections: microbiological and clinical epidemiology. Ann Intern Med 1998; 129: 182–9
  • Oh J. Y., Yu H. S., Kim S. K., Seol S. Y., Cho D. T., Lee J. C. Changes in patterns of antimicrobial susceptibility and integron carriage among Shigella sonnei isolates from southwestern Korea during epidemic periods. J Clin Microbiol 2003; 41: 421–3
  • Loeffler J. M., Garbino J., Lew D., Harbarth S., Rohner P. Antibiotic consumption, bacterial resistance and their correlation in a Swiss university hospital and its adult intensive care units. Scand J Infect Dis 2003; 35: 843–50
  • Bellomo R., Bersten A. D., Boots R. J., et al. The use of antimicrobials in ten Australian and New Zealand intensive care units. The Australian and New Zealand Intensive Care Multicentre Studies Group Investigators. Anaesth Int Care 1998; 26: 648–53
  • Fridkin S. K., Steward C. D., Edwards J. R., et al. PICAREI. Hospitals, surveillance of antimicrobial use and antimicrobial resistance in United States hospitals: Project ICARE Phase 2. Clin Infect Dis 1999; 29: 245–52
  • Sintchenko V., Iredell J. R., Gilbert G. L., Coiera E. What do physicians think about evidence‐based antibiotic use in critical care? A survey of Australian intensivists and infectious disease practitioners. Intern Med J 2001; 31: 462–9
  • Sintchenko V., Iredell J. R., Gilbert G. L., Coiera E. Handheld computer based decision support reduces patient length of stay and antibiotic prescribing in critical care. J Am Med Inform Assoc 2005; 12: 398–402
  • Luna C. M., Videla A., Mattera J., et al. Blood cultures have limited value in predicting severity of illness and as a diagnostic tool in ventilator‐associated pneumonia. Chest 1999; 116: 1075–84
  • Sintchenko V., Iredell J. R., Gilbert G. L., Coiera E. What do physicians think about evidence‐based antibiotic use in critical care? A survey of Australian intensivists and infectious disease practitioners. Intern Med J 2001; 31: 462–9
  • Ambler R. The structure of β‐lactamases. Philos Tran R Soc London Soc B Biol Sci 1980; 289: 321–31
  • Bush K., Jacoby G. A., Medeiros A. A. A functional classification scheme for beta‐lactamases and its correlation with molecular structure. Antimicrob Agents Chemother 1995; 39: 1211–33
  • Jacoby G. A., Bush K. Beta‐lactamase nomenclature. J Clin Microbiol 2005; 43: 6220
  • Nikaido H., Normark S. Sensitivity of Escherichia coli to various beta‐lactams is determined by the interplay of outer membrane permeability and degradation by periplasmic beta‐lactamases: a quantitative predictive treatment. Mol Microbiol 1987; 1: 29–36
  • Peleg A. Y., Franklin C., Walters L. J., Bell J. M., Spelman D. W. OXA‐58 and IMP‐4 carbapenem‐hydrolyzing beta‐lactamases in an Acinetobacter junii blood culture isolate from Australia. Antimicrob Agents Chemother 2006; 50: 399–400
  • Peleg A. Y., Franklin C., Bell J., Spelman D. W. Emergence of IMP‐4 metallo‐β‐lactamase in a clinical isolate from Australia. J Antimicrob Chemother 2004; 54: 699–700
  • Espedido B., Iredell J., Thomas L., Zelynski A. Wide dissemination of a carbapenemase plasmid among gram‐negative bacteria: implications of the variable phenotype. J Clin Microbiol 2005; 43: 4918–9
  • Poirel L., Nordmann P. Genetic structures at the origin of acquisition and expression of the carbapenem‐hydrolyzing oxacillinase gene blaOXA‐58 in Acinetobacter baumannii. Antimicrob Agents Chemother 2006; 50: 1442–8
  • Espedido B., Iredell J. R. Carbapenem resistance in an Australian Klebsiella pneumoniae isolate: a blaIMP‐4 gene cassette in a conjugative plasmid carrying a novel blaOXA‐23 variant. Antimicrob Agents Chemother, (in press)
  • Walsh T. R., Toleman M. A., Poirel L., Nordmann P. Metallo‐β‐lactamases: the quiet before the storm?. Clin Microbiol Rev 2005; 18: 306–25
  • Peleg A. Y., Franklin C., Bell J. M., Spelman D. W. Dissemination of the metallo‐beta‐lactamase gene blaIMP‐4 among gram‐negative pathogens in a clinical setting in Australia. Clin Infect Dis 2005; 41: 1549–56
  • Jones R. N., Biedenbach D. J., Sader H. S., Fritsche T. R., Toleman M. A., Walsh T. R. Emerging epidemic of metallo‐b‐lactamase–mediated resistances. Diagn Microbiol Infect Dis 2005; 51: 77–84
  • Espedido B., George A. M., Hall R. M., Iredell J. R. High‐level carbapenem resistance in Klebsiella, MicroNZ, Combined Annual Scientific Meeting and Exhibition of the Australian and New Zealand Societies for Microbiology, 28 September‐2 October 2003, Auckland, New Zealand
  • Peleg A. Y., Bell J. M., Hofmeyr A., Wiese P. Inter‐country transfer of Gram‐negative organisms carrying the VIM‐4 and OXA‐58 carbapenem‐hydrolysing enzymes. J Antimicrob Chemother 2006; 57: 794–5
  • Clinical and Laboratory Standards Institute (CLSI). Performance Standards for Antimicrobial Susceptibility Testing: Fifteenth Informational Supplement. M100‐S15. CLSI, Wayne, PA 2005
  • Arakawa Y., Shibata N., Shibayama K., et al. Convenient test for screening metallo‐beta‐lactamase‐producing gram‐negative bacteria by using thiol compounds. J Clin Microbiol 2000; 38: 40–3
  • Lee K., Yong D., Yum J. H., et al. Evaluation of Etest MBL for detection of blaIMP‐1 and blaVIM‐2 allele‐positive clinical isolates of Pseudomonas spp. and Acinetobacter spp. J Clin Microbiol 2005; 43: 942–4
  • Yan J. J., Wu J. J., Tsai S. H., Chuang C. L. Comparison of the double‐disk, combined disk, and Etest methods for detecting metallo‐beta‐lactamases in gram‐negative bacilli. Diagn Microbiol Infect Dis 2004; 49: 5–11
  • Turnidge J, Bell J, Pearson J, Franklin C. 2005. On behalf of the Australian Group for Antimicrobial Resistance (AGAR). Gram Negative Survey: 2004 Antimicrobial Susceptibility Report. Http://www.agargroup.org/surveys/GNB_04_susceptibility_report.pdf (accessed Oct 2006)
  • Thomas L., Espedido B., Watson S., Iredell J. Forewarned is forearmed: antibiotic resistance gene surveillance in critical care. J Hosp Infect 2005; 60: 291–3
  • Hernandez‐Alles S., Benedi V. J., Martinez‐Martinez L., et al. Development of resistance during antimicrobial therapy caused by insertion sequence interruption of porin genes. Antimicrob Agents Chemother 1999; 43: 937–9
  • Epp S. F., Kohler T., Plesiat P., Michea‐Hamzehpour M., Frey J., Pechere J‐C. C‐terminal region of Pseudomonas aeruginosa outer membrane porin OprD modulates susceptibility to meropenem. Antimicrob Agents Chemother 2001; 45: 1780–7
  • Espedido B., Cheong E., Power F., Iredell J. Behaviour of an Australian carbapenemase outbreak: C2‐106, American Society for Microbiology, 45th Interscience Conference on Antimicriobial Agents and Chemotherapy, December 16–19, 2005, Washington DC, USA
  • Partridge S., Cerca N., Mach L., Iredell J. Bla TEM genes in Enterobacteriaceae from Australian intensive care patients., American Society for Microbiology, 46th Interscience Conference on Antimicriobial Agents and Chemotherapy, September 27–30, 2005, San Francisco, USA
  • Nielsen K. M., Smalla K., van Elsas J. Natural transformation of Acinetobacter sp. strain bd413 with cell lysates of Acinetobacter sp., Pseudomonas fluorescens, and Burkholderia cepacia in Soil Microcosms. Appl Environ Microbiol 2000; 66: 206–12
  • Kersulyte D., Chalkauskas H., Berg D. E. Emergence of recombinant strains of Helicobacter pylori during human infection. Mol Microbiol 1999; 31: 31–44
  • Hinnebusch B. J., Rosso M‐L., Schwan T. G., Carniel E. High‐frequency conjugative transfer of antibiotic resistance genes to Yersinia pestis in the flea midgut. Mol Microbiol 2002; 46: 349–54
  • Lakaye B., Dubus A., Lepage S., Groslambert S., Frère J‐M. When drug inactivation renders the target irrelevant to antibiotic resistance: a case story with β‐lactams. Mol Microbiol 1999; 31: 89–101
  • Martinez‐Freijo P., Fluit A. C., Schmidt F‐J., Grek V. S. C., Verhoef J., Jones M. E. Class I integrons in Gram‐negative isolates from different European hospitals and association with decreased susceptibility to multiple antibiotic compounds. J Antimicrob Chemother 1998; 42: 689–96
  • Leverstein‐van Hall M. A., Paauw A., Box A. T. A., Blok H. E. M., Verhoef J., Fluit A. C. Presence of integron‐associated resistance in the community is widespread and contributes to multidrug resistance in the hospital. J Clin Microbiol 2002; 40: 3038–40
  • Brown D. F. Detection of methicillin/oxacillin resistance in staphylococci. J Antimicrob Chemother 2001; 48 (Suppl 1): 65–70
  • Chambers H. F. Methicillin resistance in staphylococci: molecular and biochemical basis and clinical implications. Clin Microbiol Rev 1997; 10: 781–91
  • Martineau F., Picard F. J., Lansac N., et al. Correlation between the resistance genotype determined by multiplex PCR assays and the antibiotic susceptibility patterns of Staphylococcus aureus and Staphylococcus epidermidis. Antimicrob Agents Chemother 2000; 44: 231–8
  • Thomas L., Olma T., Iredell J. R. Infection control in the crtitically ill: a new approach to studying the silent majority, MicroNZ, Combined Annual Scientific Meeting and Exhibition of the Australian and New Zealand Societies for Microbiology, 28 September–2 October 2003, Auckland, New Zealand
  • Iredell J., Sintchenko V. Screening for carbapenem resistance in Gram‐negative bacteria. Lancet Infect Dis 2006; 6: 316–7
  • Poirel L., Nordmann P. Acquired carbapenem‐hydrolyzing β‐lactamases and their genetic support. Current Pharmaceutical Biotechnology 2002; 3: 117–27
  • Walsh T. R., Bolmstrom A., Qwarnstrom A., Gales A. Evaluation of a new Etest for detecting metallo‐β‐lactamases in routine clinical testing. J Clin Microbiol 2002; 40: 2755–9
  • Franklin C., Liolios L., Peleg A. Y. Phenotypic detection of carbapenem‐susceptible metallo‐β‐lactamase‐producing Gram‐negative bacilli in the clinical laboratory. J Clin Microbiol 2006; 44: 3139–44
  • Tenover F. C., Kalsi R. K., Williams P. P., et al. Carbapenem resistance in Klebsiella pneumoniae not detected by automated susceptibility testing. Emerg Infect Dis 2006; 12: 1209–13

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