50
Views
5
CrossRef citations to date
0
Altmetric
INVITED REVIEW

Outcome prediction for renal cell carcinoma: evaluation of prognostic factors for tumours divided according to histological subtype

, &
Pages 459-465 | Received 25 May 2007, Accepted 04 Jun 2007, Published online: 06 Jul 2009

References

  • Srigley J. R., Hutter R. V. P., Gelb A. B., et al. Current prognostic factors – renal cell carcinoma. Cancer 1997; 80: 994–6
  • Delahunt B., Eble J. N. History of the development of classification of renal cell neoplasia. Clin Lab Med 2005; 25: 231–46
  • Amin M. B., Amin M. B., Tamboli P., et al. Prognostic impact of histologic subtyping of adult renal epithelial neoplasms. An experience of 405 cases. Am J Surg Pathol 2002; 26: 281–91
  • Moch H., Grasser T., Amin M. B., et al. Prognostic utility of the recently recommended histologic classification and revised TNM staging system of renal cell carcinoma. A Swiss experience with 588 tumors. Cancer 2000; 89: 604–14
  • Cheville J. C., Lohse C. M., Zincke H., Weaver A. L., Blute M. L. Comparison of outcome and prognostic features among histologic subtypes of renal cell carcinoma. Am J Surg Pathol 2003; 27: 612–24
  • Kim H., Cho N. H., Kim D., et al. Renal cell carcinoma in South Korea: A multicenter study. Hum Pathol 2004; 35: 1556–63
  • Patard J., Leray E., Rioux‐Leclercq N., et al. Prognostic value of histologic subtypes in renal cell carcinoma: A multicenter experience. J Clin Oncol 2005; 23: 2763–71
  • Ljungberg B., Alamdri F. I., Stenling R., et al. Prognostic significance of the Heidelberg classification of renal cell carcinoma. Eur Urol 1999; 36: 565–9
  • Gudbjartsson T., Hardarson S., Petursdottir V., et al. Histological subtyping and nuclear grading of renal cell carcinoma and their implications for survival: A retrospective nation‐wide study of 629 patients. Eur Urol 2005; 48: 593–600
  • Delahunt B., Eble J. N. Papillary renal cell carcinoma: A clinicopathologic and immunohistochemical study of 105 tumors. Mod Pathol 1997; 10: 537–44
  • Leroy X., Zini L., Leteurtre E., et al. Morphologic subtyping of papillary renal cell carcinoma. Correlation with prognosis and differential expression of MUC1 between the two subtypes. Mod Pathol 2002; 15: 1126–30
  • Delahunt B., Eble J. N., McCredie M. R. E., et al. Morphologic typing of papillary renal cell carcinoma: comparison of growth kinetics and patient survival in 66 cases. Hum Pathol 2001; 32: 590–5
  • Pignot G., Elie C Conquy S., et al. Survival analysis of 130 patients with papillary renal cell carcinoma: prognostic utility of type 1 and type 2 subclassification. Urology 2007; 69: 230–5
  • Alloy Y., Ouazana D., Boucher E., Thiounn N., Vieillefond A. Papillary renal cell carcinoma. Prognostic value of morphological subtypes in a clinicopathological study of 43 cases. Virchows Arch 2003; 442: 336–42
  • Tickoo S., Reuter V. Subtyping of papillary renal cell carcinoma. A clinicopathologic study of 103. Mod Pathol 2001; 14: 124A (abstr)
  • Xang X. J., Tan M. H., Kim H. L., et al. A molecular subclassification of papillary renal cell carcinoma. Cancer Res 2005; 65: 5628–31
  • Sika‐Paotonu D., Bethwaite P. B., McCredie M. R. E., Jordan T. W., Delahunt B. Nucleolar grade but not Fuhrman grade is applicable to papillary renal cell carcinoma. Am J Surg Pathol 2006; 30: 1091–6
  • Delahunt B. Histopathologic prognostic indicators for renal cell carcinoma. Semin Diagn Pathol 1998; 15: 68–76
  • Fuhrman S. A., Lasky L. C., Limas C. Prognostic significance of morphologic parameters in renal cell carcinoma. Am J Surg Pathol 1982; 6: 655–63
  • Ficarra V., Martignoni G., Maffei N., et al. Original and reviewed nuclear grading according to the Fuhrman system: a multivariate analysis of 388 patients with conventional renal cell carcinoma. Cancer 2005; 103: 68–75
  • Lohse C. M., Blute M. L., Zincke H., Weaver A. L., Cheville J. C. Comparison of standardized and non‐standardized nuclear grade of renal cell carcinoma to predict outcome among 2,042 patients. Am J Clin Pathol 2002; 118: 877–86
  • Cheville J. C., Zincke H., Lohse C. M., et al. pT1 clear cell renal cell carcinoma. A study of the association between MIB‐1 proliferative activity and pathologic features and cancer specific survival. Cancer 2002; 94: 2180–4
  • Lanigan D., Conroy R., Barry‐Walsh C., et al. A comparative analysis of grading systems in renal adenocarcinoma. Histopathology 1994; 24: 473–6
  • Nazeer T., Amin M. B., Delahunt B., et al. Interobserver variability of nuclear grading in renal cell carcinoma. Mod Pathol 1998; 11: 91A
  • Murphy W. M., Grignon D. J., Perlman E. Tumors of the Kidney, Bladder and Related Structures. AFIP, Washington 2004, 4th Series, Fascicle 1
  • Delahunt B., Sika‐Paotonu D., Bethwaite P. B., et al. Fuhrman grading is not appropriate for chromophobe renal cell carcinoma. Am J Surg Pathol 2007; 31: 957–60
  • Delahunt B. Sarcomatoid renal cell carcinoma: The final common dedifferentiation pathway of renal epithelial malignancies. Pathology 1999; 31: 185–90
  • Cheville J. C., Lohse C. M., Zincke H., et al. Sarcomatoid renal cell carcinoma. An examination of underlying histologic subtype and an analysis of associations with patient outcome. Am J Surg Pathol 2004; 28: 435–41
  • Kuroima K., Kinoshita Y., Shiratsuchit H., et al. Renal cell carcinoma with rhabdoid features: an aggressive neoplasm. Histopathology 2002; 41: 538–48
  • Tannapfel A., Hahn H. A., Katalinic A., et al. Prognostic nature of ploidy and proliferation markers in renal cell carcinoma. Cancer 1996; 77: 164–71
  • Delahunt B., Ribas J. L., Nacey J. N., Bethwaite P. B. Nucleolar organizer regions and prognosis in renal cell carcinoma. J Pathol 1991; 164: 31–7
  • Delahunt B., Bethwaite P. B., Thornton A., Ribas J. L. Proliferation of renal cell carcinoma assessed by fixation‐resistant polyclonal Ki‐67 antibody labeling. Correlation with clinical outcome. Cancer 1995; 75: 2714–9
  • Delahunt B., Kittelson J. M., McCredie M. R. E., et al. Prognostic importance of tumor size for localized conventional (clear cell) renal cell carcinoma. Cancer 2002; 94: 658–64
  • Gelb A. B., Sudilovsky D., Wu C. D., Weiss L. M., Medeiros L. J. Appraisal of intratumoral microvessel diversity, MIB‐1 score, DNA content and p53 protein expression as prognostic indicators in patients with locally confined renal cell carcinoma. Cancer 1997; 80: 1768–75
  • Moch H., Sauter G., Buchholz N., et al. Epidermal growth factor receptor expression is associated with rapid tumour cell proliferation in renal cell carcinoma. Hum Pathol 1997; 28: 1255–9
  • Kankuri M., Soderstrom K. O., Pelliniemi T. T., et al. The association of immunoreactive p53 and Ki‐67 with T‐stage, grade, occurrence of metastases and survival in renal cell carcinoma. Anticancer Res 2006; 26: 3825–33
  • Yildiz E., Gokce G., Kilicarslan H., et al. Prognostic value of the expression of Ki‐67, CD44 and vascular endothelial growth factor, and microvessel invasion in renal cell carcinoma. BJU Int 2004; 93: 1087–93
  • Delahunt B., Eble J. N., McCredie M. R. E. Morphologic typing of papillary renal cell carcinoma: comparison of growth kinetics and patient survival in 66 cases. Hum Pathol 2001; 32: 590–5
  • Yang R. M., Naitoh J., Hengst L., Reed S. I. Translational control of p27Kip1 accumulation during the cell cycle. Science 1996; 271: 1861–4
  • Migita T., Oda Y., Naito S., Tsuneyoshi M. Low‐expression of p27Kip1 is associated with tumor size and poor prognosis in patients with renal cell carcinoma. Cancer 2002; 94: 973–9
  • Weiss R. H., Borowsky A. D., Seligson D., et al. p21 is a prognostic marker for renal cell carcinoma. Implications for novel therapeutic approaches. J Urol 2007; 177: 63–9
  • Lipponen P., Eskelinen M., Hietala K., et al. Expression of proliferating cell nuclear antigen (PC10), p53 protein and c‐erbB‐2 in renal adenocarcinoma. Int J Cancer 1994; 57: 275–80
  • Oda H., Nakatsuru Y., Ishikawa T. Mutation of the p53 gene and p53 protein over‐expression are associated with sarcomatoid transformation in renal cell carcinoma. Cancer Res 1995; 55: 658–62
  • Imai Y., Strohmeyer T. G., Fleischhacker M., Slamon D. J., Koeffler H. P. p53 mutations and MDM‐2 amplification in renal cell cancers. Mod Pathol 1994; 7: 766–70
  • Phuoc N. B., Ehara H., Gotoh T., et al. Immunohistochemical analysis with multiple antibodies in search of prognostic markers for clear cell renal cell carcinoma. Urology 2007; 69: 843–8
  • Gobe G., Rubin M., Williams G Sawczuk I., Buttyan R. Apoptosis and expression of Bcl‐2, Bcl‐XL and Bax in renal cell carcinomas. Cancer Invest 2002; 20: 324–32
  • Dosquet C., Condert M. C., Lepage E., Cabane J., Richard E. Are angiogenic factors, cytokines and soluble adhesion molecules prognostic factors in patients with renal cell carcinoma?. Clin Cancer Res 1997; 3: 2451–8
  • Itoi T., Yamana K., Bilim V., Tokahashi K., Tomita F. Impact of frequent Bcl‐2 expression on better prognosis in renal cell carcinoma?. Br J Cancer 2004; 90: 2000–5
  • Joo H. J., Oh D. K., Kim Y. S., Lee K. B., Kim S. J. Increased expression of caveolin‐1 and microvessel density correlates with metastases and poor prognosis in clear cell renal cell carcinoma. BJU Int 2004; 93: 291–6
  • Fukata S., Inone K., Kamada N., et al. Levels of angiogenesis and expression of angiogenesis‐related genes are prognostic for organ‐specific metastases of renal cell carcinoma. Cancer 2005; 103: 931–42
  • MacLennan G. T., Bostwick D. G. Microvessel density in renal cell carcinoma: Lack of prognostic significance. Urology 1995; 46: 27–30
  • Lee J. S., Kim H. S., Jung J. J., Park C. S., Lee M. C. Expression of vascular endothelial growth factor in renal cell carcinoma and the relation to angiogenesis and p53 protein expression. J Surg Oncol 2001; 77: 55–60
  • Delahunt B., Bethwaite P. B., Thornton A. Prognostic significance of microscopic vascularity for clear cell renal cell carcinoma. Br J Urol 1997; 80: 401–4
  • Yoshimo S., Kato M., Okada K. Evaluation of the prognostic significance of microvessel count and tumor size in renal cell carcinoma. Int J Urol 1998; 5: 119–23
  • Rioux‐Leclercq N., Epstein J. I., Bansard J. Y., et al. Clinical significance of cell proliferation, microvessel density and CD44 adhesion molecule expression in renal cell carcinoma. Hum Pathol 2001; 32: 1209–15
  • Imao T., Egawa M., Takashima H., Koshida K., Namiki M. Inverse correlation of microvessel density with metastases and prognosis in renal cell carcinoma. Int J Urol 2004; 11: 948–53
  • Sandlund J., Hedberg Y., Bergh A., et al. Endoglin (CD105) expression in human renal cell carcinoma. BJU Int 2006; 97: 706–10
  • Gilcranse M. Z., Guzman‐Paz M., Niehans G., et al. Correlation of CD44S expression in renal clear cell carcinomas with subsequent tumor progression or recurrence. Cancer 1999; 86: 2320–6
  • Jin J. S., Yu C. P., Sun G. H., et al. Increasing expression of fascin in renal cell carcinoma associated with clinicopathological parameters of aggressiveness. Histol Histpathol 2006; 21: 1287–93
  • Petraki C. D., Gregorakis A. K., Vaslamatzis M. M., et al. Prognostic implications of the immunohistochemical expression of human kallikreins 5, 6, 10 and 11 in renal cell carcinoma. Tumour Biol 2006; 27: 1–7
  • Lidgren A., Hedberg Y., Grankvist K., et al. The expression of hypoxia‐inducible factor 1 alpha is a favorable independent prognostic factor in renal cell carcinoma. Clin Cancer Res 2005; 11: 1129–35
  • Costes V., Liantard J., Picot M‐C., et al. Expression of the Interleukin‐6 receptor in primary renal cell carcinoma. J Clin Pathol 1997; 50: 835–40
  • Jin J. S., Hsieh D. S., Lin Y. F., et al. Increasing expression of extracellular matrix metalloprotease inducer in renal cell carcinoma. Tissue microarray analysis of immunostaining score with clinicopathological parameters. Int J Urol 2006; 13: 573–80
  • Leroy X., Zercmech F., Zini L., et al. MUC1 expression is correlated with nuclear grade and progression in TI renal cell carcinoma. Am J Clin Pathol 2002; 118: 47–51
  • Matusan K., Dordevic G., Stipic D., Mozetic V., Lucin K. Osteopontin expression correlates with prognostic variables and survival in clear cell renal cell carcinoma. J Surg Oncol 2006; 94: 325–31
  • Robson C. J., Churchill B. M., Anderson W. The results of radical nephrectomy for renal cell carcinoma. J Urol 1969; 101: 297–301
  • Green F. L., Page D. L., Fleming I. D., et al. AJCC Cancer Staging Manual. 2002, 6th ed. Springer: New York
  • Svatek R. S., Lotan Y., Hermann M., et al. The influence of clinical and pathological staging discrepancy on cancer specific survivals in patients treated for renal cell carcinoma. J Urol 2006; 176: 1321–5
  • Delahunt B., Eble J. N. Papillary adenoma of the kidney. An evolving concept. J Urol Pathol 1997; 7: 99–112
  • Sobin L. H., Wittekind Ch. TNM Classification of Malignant Tumours. 1997, 5th ed. Wiley‐Liss: New York
  • Gofrit O. N., Shapiro A., Pizov G., et al. Does stage T3a renal cell carcinoma embrace a homogenous group of patients?. J Urol 2007; 177: 2604–8
  • Bonsib S. M. T2 clear cell renal cell carcinoma is a rare entity: a study of 120 clear cell renal cell carcinomas. J Urol 2005; 174: 1199–202
  • Thompson R. H., Leibovich B. C., Cheville J. C., et al. Is renal sinus fat invasion the same as perinephric fat invasion for pT3a renal cell carcinoma?. J Urol 2005; 174: 1218–21
  • Bonsib S. M. Renal veins and venous extension in clear cell renal cell carcinoma. Mod Pathol 2007; 20: 44–53
  • Bonsib S. M. Renal lymphatics and lymphatic involvement in sinus vein invasive (pT3b) clear cell renal cell carcinoma. A study of 40 cases. Mod Pathol 2006; 19: 746–53
  • Leibovich B. C., Blute M. L., Cheville C. M., et al. Prediction of progression after radical nephrectomy for patients with clear cell renal cell carcinoma. A stratification tool for prospective clinical trials. Cancer 2003; 97: 1663–71
  • Sorbollini M., Kattan M. W., Snyder M. E., et al. A postoperative prognostic nomogram predicting recurrence for patients with conventional clear cell renal cell carcinoma. J Urol 2005; 173: 48–51
  • Hupertan V., Roupret M., Poisson J. F., et al. Low predictive accuracy of the Kattan postoperative predictive nomogram for renal cell carcinoma recurrence in a population of French patients. Cancer 2006; 107: 2523–4

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.