A predictive nomogram incorporating gait speed for all-cause mortality in hospitalized cirrhotics

References

• Fried LP, Tangen CM, Walston J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001 Mar;56(3):M146–56.
   PubMed Web of Science ®Google Scholar
• Lai JC, Sonnenday CJ, Tapper EB, et al. Frailty in liver transplantation: an expert opinion statement from the American society of transplantation liver and intestinal community of practice. Am J Transplant. 2019 Jul;19(7):1896–1906.
   PubMed Web of Science ®Google Scholar
• Kiani S, Stebbins A, Thourani VH, et al. The effect and relationship of frailty indices on survival after transcatheter aortic valve replacement. JACC Cardiovasc Interv. 2020 Jan 27;13(2):219–231.
   PubMed Web of Science ®Google Scholar
• Dunn MA, Josbeno DA, Tevar AD, et al. Frailty as tested by gait speed is an independent risk factor for cirrhosis complications that require hospitalization. Am J Gastroenterol. 2016 Dec;111(12):1768–1775.
   PubMed Web of Science ®Google Scholar
• Salim TI, Nestlerode LC, Lucatorto EL, et al. Frailty as tested by gait speed is a risk factor for liver transplant respiratory complications. Am J Gastroenterol. 2020 Jun;115(6):859–866.
   PubMed Web of Science ®Google Scholar
• Kulkarni SS, Chen H, Josbeno DA, et al. Gait speed and grip strength are associated with dropping out of the liver transplant waiting list. Transplant Proc. 2019 Apr;51(3):794–797.
   PubMed Web of Science ®Google Scholar
• Deng Y, Lin L, Fan X, et al. Incorporation of frailty estimated by gait speed within MELD-Na and the predictive potential for mortality in cirrhosis. Ther Adv Chronic Dis. 2020;11:2040622320922023.
   Web of Science ®Google Scholar
• Cruz-Jentoft AJ, Bahat G, Bauer J, et al. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019 Jan 1;48(1):16–31.
   PubMed Web of Science ®Google Scholar
• Kok B, Whitlock R, Ferguson T, et al. Health-related quality of life: a rapid predictor of hospitalization in patients with cirrhosis. Am J Gastroenterol. 2020 Apr;115(4):575–583.
   PubMed Web of Science ®Google Scholar
• Deng Y, Lin L, Hou L, et al. A self-reported Frailty Index predicts long-term mortality in hospitalized patients with cirrhosis. Ann Transl Med. 2020 Oct;8(19):1217.
   PubMed Web of Science ®Google Scholar
• Iasonos A, Schrag D, Raj GV, et al. How to build and interpret a nomogram for cancer prognosis. J Clin Oncol. 2008 Mar 10;26(8):1364–1370.
   PubMed Web of Science ®Google Scholar
• Lai JC, Covinsky KE, McCulloch CE, et al. The liver frailty index improves mortality prediction of the subjective clinician assessment in patients with cirrhosis. Am J Gastroenterol. 2018 Feb;113(2):235–242.
   PubMed Web of Science ®Google Scholar
• Puchades L, Chau S, Dodson JA, et al. Association of cardiac abnormalities to the frail phenotype in cirrhotic patients on the waitlist: from the functional assessment in liver transplantation study. Transplantation. 2018 Mar;102(3):e101–e107.
   PubMed Web of Science ®Google Scholar
• Weissenborn K, Ruckert N, Hecker H, et al. The number connection tests A and B: interindividual variability and use for the assessment of early hepatic encephalopathy. J Hepatol. 1998 Apr;28(4):646–653.
   PubMed Web of Science ®Google Scholar
• Wang CW, Lebsack A, Chau S, et al. The range and reproducibility of the liver frailty index. Liver Transpl. 2019 Jun;25(6):841–847.
   PubMed Web of Science ®Google Scholar
• Yang F, Lin L, Jiang X, et al. Increasing diverticulosis in an aging population: a colonoscopy-based study of 5-year trends in 26 463 patients in Northern China. Med Sci Monit. 2018 May 6;24:2825–2831.
   PubMed Web of Science ®Google Scholar
• Lal S, Gray A, Kim E, et al. Frailty in elderly patients undergoing cardiac surgery increases hospital stay and 12-month readmission rate. Heart Lung Circ. 2019 Dec 5;29(8):1187–1194.
   PubMed Web of Science ®Google Scholar
• Fried LP, Hadley EC, Walston JD, et al. From bedside to bench: research agenda for frailty. Sci Aging Knowl Environ. 2005 Aug 3;2005(31):e24.
   Google Scholar
• Carvalho JR, Vasconcelos M, Marques da Costa P, et al. Identifying palliative care needs in a Portuguese liver unit. Liver Int. 2018 Nov;38(11):1982–1987.
   PubMed Web of Science ®Google Scholar
• Schuppan D, Afdhal NH. Liver cirrhosis. Lancet. 2008 Mar 8;371(9615):838–851.
   PubMed Web of Science ®Google Scholar
• Soto R, Diaz LA, Rivas V, et al. Frailty and reduced gait speed are independently related to mortality of cirrhotic patients in long-term follow-up. Ann Hepatol. 2021 Feb;14(25):100327.
   Web of Science ®Google Scholar
• Bunchorntavakul C, Reddy KR. Review article: malnutrition/sarcopenia and frailty in patients with cirrhosis. Aliment Pharmacol Ther. 2020 Jan;51(1):64–77.
   PubMed Web of Science ®Google Scholar
• Peng JK, Hepgul N, Higginson IJ, et al. Symptom prevalence and quality of life of patients with end-stage liver disease: a systematic review and meta-analysis. Palliat Med. 2019 Jan;33(1):24–36.
   PubMed Web of Science ®Google Scholar
• Balachandran VP, Gonen M, Smith JJ, et al. Nomograms in oncology: more than meets the eye. Lancet Oncol. 2015 Apr;16(4):e173–80.
   PubMed Web of Science ®Google Scholar
• Peterson CL, Hall AL, Kautz SA, et al. Pre-swing deficits in forward propulsion, swing initiation and power generation by individual muscles during hemiparetic walking. J Biomech. 2010 Aug 26;43(12):2348–2355.
   PubMed Web of Science ®Google Scholar
• Shah RC, Buchman AS, Boyle PA, et al. Musculoskeletal pain is associated with incident mobility disability in community-dwelling elders. J Gerontol A Biol Sci Med Sci. 2011 Jan;66(1):82–88.
   PubMed Web of Science ®Google Scholar
• Peel NM, Kuys SS. Walking activity of older patients in rehabilitation: a prospective study. J Frailty Aging. 2013;2(1):22–26.
   PubMedGoogle Scholar
• Mwaka-Rutare C, Perreault K, Abedi-Mukutenga P, et al. Activity and participation in stroke survivors in a low-income setting: a cross-sectional study. Physiother Res Int. 2020;20:e1846.
   Google Scholar
• Dean CM, Ada L, Lindley RI. Treadmill training provides greater benefit to the subgroup of community-dwelling people after stroke who walk faster than 0.4m/s: a randomised trial. J Physiother. 2014 Jun;60(2):97–101.
   PubMed Web of Science ®Google Scholar
• Boyne P, Meyrose C, Westover J, et al. Effects of exercise intensity on acute circulating molecular responses poststroke. Neurorehabil Neural Repair. 2020 Mar;34(3):222–234.
   PubMed Web of Science ®Google Scholar
• Dellatore P, Cheung M, Mahpour NY, et al. Clinical manifestations of hepatic encephalopathy. Clin Liver Dis. 2020 May;24(2):189–196.
   PubMed Web of Science ®Google Scholar
• Bajaj JS, Duarte-Rojo A, Xie JJ, et al. Minimal hepatic encephalopathy and mild cognitive impairment worsen quality of life in elderly patients with cirrhosis. Clin Gastroenterol Hepatol. 2020 Dec;18(13):3008–3016 e2.
   PubMed Web of Science ®Google Scholar
• Lai JC, Dodge JL, McCulloch CE, et al. Frailty and the burden of concurrent and incident disability in patients with cirrhosis: a prospective cohort study. Hepatol Commun. 2020 Jan;4(1):126–133.
   PubMed Web of Science ®Google Scholar
• Tapper EB, Derstine B, Baki J, et al. Bedside measures of frailty and cognitive function correlate with sarcopenia in patients with cirrhosis. Dig Dis Sci. 2019 Dec;64(12):3652–3659.
   PubMed Web of Science ®Google Scholar
• Rockwood K, Song X, MacKnight C, et al. A global clinical measure of fitness and frailty in elderly people. CMAJ. 2005 Aug 30;173(5):489–495.
   PubMed Web of Science ®Google Scholar
• Sze S, Pellicori P, Zhang J, et al. Identification of frailty in chronic heart failure. JACC Heart Fail. 2019 Apr;7(4):291–302.
   PubMed Web of Science ®Google Scholar