Advanced search
Publication Cover
Postgraduate Medicine Volume 133, 2021 - Issue 7
Submit an article Journal homepage
270
Views
10
CrossRef citations to date
0
Altmetric
Clinical features - Original Research

Utility of biomarkers in predicting complicated appendicitis: can immature granulocyte percentage and C-reactive protein be used?

Ali Güngöra Department of Pediatric Emergency Medicine, Dr. Sami Ulus Maternity and Child Health and Diseases Training and Research Hospital, Ankara, TurkeyCorrespondence[email protected]
ORCID Iconhttps://orcid.org/0000-0003-4139-3480
ORCID Icon,
Aytaç Göktuğa Department of Pediatric Emergency Medicine, Dr. Sami Ulus Maternity and Child Health and Diseases Training and Research Hospital, Ankara, Turkey
,
Muhammed Mustafa Güneylioğlua Department of Pediatric Emergency Medicine, Dr. Sami Ulus Maternity and Child Health and Diseases Training and Research Hospital, Ankara, Turkey
,
Raziye Merve Yaradılmışa Department of Pediatric Emergency Medicine, Dr. Sami Ulus Maternity and Child Health and Diseases Training and Research Hospital, Ankara, Turkey
,
ilknur Bodura Department of Pediatric Emergency Medicine, Dr. Sami Ulus Maternity and Child Health and Diseases Training and Research Hospital, Ankara, Turkey
,
Betül Öztürka Department of Pediatric Emergency Medicine, Dr. Sami Ulus Maternity and Child Health and Diseases Training and Research Hospital, Ankara, Turkey
,
İbrahim Karamanb Department of Pediatric Surgery, Dr. Sami Ulus Maternity and Child Health and Diseases Training and Research Hospital, Ankara, Turkey
,
Can Demir Karacana Department of Pediatric Emergency Medicine, Dr. Sami Ulus Maternity and Child Health and Diseases Training and Research Hospital, Ankara, Turkey
&
Nilden Tuyguna Department of Pediatric Emergency Medicine, Dr. Sami Ulus Maternity and Child Health and Diseases Training and Research Hospital, Ankara, Turkey
 show all
Pages 817-821 | Received 08 May 2021, Accepted 23 Jun 2021, Published online: 09 Jul 2021

References

  • Reynolds SL, Jaffe DM. Diagnosing abdominal pain in a pediatric emergency department. Pediatr Emerg Care. 1992;8(3):126–128.
  • Magnúsdóttir MB, Róbertsson V, Þorgrímsson S, et al. Abdominal pain is a common and recurring problem in paediatric emergency departments. Acta Paediatr. 2019;108(10):1905–1910.
  • Rentea RM, St Peter SD. Pediatric appendicitis. Surg Clin North Am. 2017;97(1):93–112.
  • Williams RF, Blakely ML, Fischer PE, et al. Diagnosing ruptured appendicitis preoperatively in pediatric patients. J Am Coll Surg. 2009;208(5):819–825.
  • Acharya A, Markar SR, Ni M, et al. Biomarkers of acute appendicitis: systematic review and cost-benefit trade-off analysis. Surg Endosc. 2017;31(3):1022–1031.
  • Beltrán MA, Almonacid J, Vicencio A, et al. Predictive value of white blood cell count and C-reactive protein in children with appendicitis. J Pediatr Surg. 2007;42(7):1208–1214.
  • Malia L, Sturm JJ, Smith SR, et al. Predictors for acute appendicitis in children. Pediatr Emerg Care. 2019 May 24. DOI:10.1097/PEC.0000000000001840.
  • Pavare J, Grope I, Gardovska D. Assessment of immature granulocytes percentage to predict severe bacterial infection in Latvian children: an analysis of secondary data. Medicina (Kaunas). 2018;54(4):56.
  • Zeng L, Wang S, Lin M, et al. Evaluation of time to positivity for blood culture combined with immature granulocytes, neutrophil-to-lymphocyte ratio, and CRP in identifying bloodstream coagulase-negative Staphylococci infection in pediatric patients. J Clin Lab Anal. 2020;34(11):e23473.
  • van der Geest PJ, Mohseni M, Brouwer R, et al. Immature granulocytes predict microbial infection and its adverse sequelae in the intensive care unit. J Crit Care. 2014;29(4):523–527. .
  • Park JS, Kim JS, Kim YJ, et al. Utility of the immature granulocyte percentage for diagnosing acute appendicitis among clinically suspected appendicitis in adult. J Clin Lab Anal. 2018;32(7):e22458. .
  • Shin DH, Cho YS, Cho GC, et al. Delta neutrophil index as an early predictor of acute appendicitis and acute complicated appendicitis in adults. World J Emerg Surg. 2017;12(1):32.
  • Maenhout TM, Marcelis L. Immature granulocyte count in peripheral blood by the Sysmex haematology XN series compared to microscopic differentiation. J Clin Pathol. 2014;67(7):648–650
  • Glass CC, Rangel SJ. Overview and diagnosis of acute appendicitis in children. Semin Pediatr Surg. 2016;25(4):198–203.
  • D’Souza N, Karim D, Sunthareswaran R. Bilirubin; a diagnostic marker for appendicitis. Int J Surg. 2013;11(10):1114–1117.
  • Sack U, Biereder B, Elouahidi T, et al. Diagnostic value of blood inflammatory markers for detection of acute appendicitis in children. BMC Surg. 2006;6:15.
  • Zani A, Teague WJ, Clarke SA, et al. Can common serum biomarkers predict complicated appendicitis in children? Pediatr Surg Int. 2017;33(7):799–805.
  • Sengul S, Guler Y, Calis H, et al. The role of serum laboratory biomarkers for complicated and uncomplicated appendicitis in adolescents. J Coll Physicians Surg Pak. 2020;30(4):420–424.
  • Korkut M, Bedel C, Selvi F. Are immature granulocytes and derivatives early predictors of acute appendicitis and acute complicated appendicitis in adults? Formos J Surg. 2020;53:123–127.
  • Ünal Y. A new and early marker in the diagnosis of acute complicated appendicitis: immature granulocytes. Ulus Travma Acil Cerrahi Derg. 2018;24(5):434–439.
  • Mathews EK, Griffin RL, Mortellaro V, et al. Utility of immature granulocyte percentage in pediatric appendicitis. J Surg Res. 2014;190(1):230–234.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.