Toll‐like receptor 4 polymorphism is associated with coronary stenosis but not with the occurrence of acute or old myocardial infarctions

References

• Martin M. U., Wesche H. Summary and comparison of the signaling mechanisms of the Toll/interleukin‐1 receptor family. Biochim Biophys Acta 2002; 1592: 265–80
   PubMed Web of Science ®Google Scholar
• Kiechl S., Lorenz E., Reindl M., Wiedermann C. J., Oberhollenzer F., Bonora E., et al. Toll‐like receptor 4 polymorphisms and atherogenesis. N Engl J Med 2002; 347: 185–92
   PubMed Web of Science ®Google Scholar
• Edfeldt K., Swedenborg J., Hansson G. K., Yan Z. Q. Expression of Toll‐like receptors in human atherosclerotic lesions: a possible pathway for plaque activation. Circulation 2002; 105: 1158–61
   PubMed Web of Science ®Google Scholar
• Xu X. H., Shah P. K., Faure E., Equils O., Thomas L., Fishbein M. C., et al. Toll‐like receptor‐4 is expressed by macrophages in murine and human lipid‐rich atherosclerotic plaques and upregulated by oxidized LDL. Circulation 2001; 104: 3103–8
   PubMed Web of Science ®Google Scholar
• Yang X., Coriolan D., Murthy V., Schultz K., Golenbock D. T., Beasley D. Proinflammatory phenotype of vascular smooth muscle cells: role of efficient Toll‐like receptor 4 signaling. Am J Physiol Heart Circ Physiol 2005; 29: 29
   Google Scholar
• Ohashi K., Burkart V., Flohe S., Kolb H. Cutting edge: heat shock protein 60 is a putative endogenous ligand of the Toll‐like receptor‐4 complex. J Immunol 2000; 164: 558–61
   PubMed Web of Science ®Google Scholar
• Okamura Y., Watari M., Jerud E. S., Young D. W., Ishizaka S. T., Rose J., et al. The extra domain A of fibronectin activates Toll‐like receptor 4. J Biol Chem 2001; 276: 10229–33, Epub Jan 9 2001
   PubMed Web of Science ®Google Scholar
• Smiley S. T., King J. A., Hancock W. W. Fibrinogen stimulates macrophage chemokine secretion through Toll‐like receptor 4. J Immunol 2001; 167: 2887–94
   PubMed Web of Science ®Google Scholar
• Chow J. C., Young D. W., Golenbock D. T., Christ W. J., Gusovsky F. Toll‐like receptor‐4 mediates lipopolysaccharide‐induced signal transduction. J Biol Chem 1999; 274: 10689–92
   PubMed Web of Science ®Google Scholar
• Kurt‐Jones E. A., Popova L., Kwinn L., Haynes L. M., Jones L. P., Tripp R. A., et al. Pattern recognition receptors TLR4 and CD14 mediate response to respiratory syncytial virus. Nat Immunol 2000; 1: 398–401
   PubMed Web of Science ®Google Scholar
• Arbour N. C., Lorenz E., Schutte B. C., Zabner J., Kline J. N., Jones M., et al. TLR4 mutations are associated with endotoxin hyporesponsiveness in humans. Nat Genet 2000; 25: 187–91
   PubMed Web of Science ®Google Scholar
• Faure E., Equils O., Sieling P. A., Thomas L., Zhang F. X., Kirschning C. J., et al. Bacterial lipopolysaccharide activates NF‐kappaB through Toll‐like receptor 4 (TLR‐4) in cultured human dermal endothelial cells. Differential expression of TLR‐4 and TLR‐2 in endothelial cells. J Biol Chem 2000; 275: 11058–63
   PubMed Web of Science ®Google Scholar
• Brand K., Page S., Rogler G., Bartsch A., Brandl R., Knuechel R., Page M., Kaltschmidt C., Baeuerle P. A., Neumeier D. Activated transcription factor nuclear factor‐kappa B is present in the atherosclerotic lesion. J Clin Invest 1996; 97: 1715–22
   PubMed Web of Science ®Google Scholar
• Monaco C., Paleolog E. Nuclear factor kappaB: a potential therapeutic target in atherosclerosis and thrombosis. Cardiovasc Res 2004; 61: 671–82
   PubMed Web of Science ®Google Scholar
• Guha M., Mackman N. LPS induction of gene expression in human monocytes. Cell Signal 2001; 13: 85–94
   PubMed Web of Science ®Google Scholar
• Kolek M. J., Carlquist J. F., Muhlestein J. B., Whiting B. M., Horne B. D., Bair T. L., et al. Toll‐like receptor 4 gene Asp299Gly polymorphism is associated with reductions in vascular inflammation, angiographic coronary artery disease, and clinical diabetes. Am Heart J 2004; 148: 1034–40
   PubMed Web of Science ®Google Scholar
• van der Graaf C., Kullberg B. J., Joosten L., Verver‐Jansen T., Jacobs L., Van der Meer J. W., et al. Functional consequences of the Asp299Gly Toll‐like receptor‐4 polymorphism. Cytokine 2005; 30: 264–8, Epub Mar 25 2005
   PubMed Web of Science ®Google Scholar
• von Aulock S., Schroder N. W., Gueinzius K., Traub S., Hoffmann S., Graf K., et al. Heterozygous Toll‐like receptor 4 polymorphism does not influence lipopolysaccharide‐induced cytokine release in human whole blood. J Infect Dis 2003; 188: 938–43, Epub Aug 28 2003
   PubMed Web of Science ®Google Scholar
• Ameziane N., Beillat T., Verpillat P., Chollet‐Martin S., Aumont M. C., Seknadji P., et al. Association of the Toll‐like receptor 4 gene Asp299Gly polymorphism with acute coronary events. Arterioscler Thromb Vasc Biol 2003; 23: e61–4, Epub Oct 16 2003
   PubMed Web of Science ®Google Scholar
• Kolek M. J., Carlquist J. F., Muhlestein J. B., Whiting B. M., Horne B. D., Bair T. L., et al. Toll‐like receptor 4 gene Asp299Gly polymorphism is associated with reductions in vascular inflammation, angiographic coronary artery disease, and clinical diabetes. Am Heart J 2004; 148: 1034–40
   PubMed Web of Science ®Google Scholar
• Yang I. A., Holloway J. W., Ye S. TLR4 Asp299Gly polymorphism is not associated with coronary artery stenosis. Atherosclerosis 2003; 170: 187–90
   PubMed Web of Science ®Google Scholar
• Morange P. E., Tiret L., Saut N., Luc G., Arveiler D., Ferrieres J., et al. TLR4/Asp299Gly, CD14/C‐260T, plasma levels of the soluble receptor CD14 and the risk of coronary heart disease: The PRIME Study. Eur J Hum Genet 2004; 12: 1041–9
   PubMed Web of Science ®Google Scholar
• Holloway J. W., Yang I. A., Ye S. Variation in the Toll‐like receptor 4 gene and susceptibility to myocardial infarction. Pharmacogenet Genomics 2005; 15: 15–21
   PubMedGoogle Scholar
• Zee R. Y., Hegener H. H., Gould J., Ridker P. M. Toll‐like receptor 4 Asp299Gly gene polymorphism and risk of atherothrombosis. Stroke 2005; 36: 154–7, Epub Dec 2 2004
   PubMed Web of Science ®Google Scholar
• Ilveskoski E., Perola M., Lehtimäki T., Laippala P., Savolainen V., Pajarinen J., et al. Age‐dependent association of apolipoprotein E genotype with coronary and aortic atherosclerosis in middle‐aged men: an autopsy study. Circulation 1999; 100: 608–13
   PubMed Web of Science ®Google Scholar
• Isola J., DeVries S., Chu L., Ghazvini S., Waldman F. Analysis of changes in DNA sequence copy number by comparative genomic hybridization in archival paraffin‐embedded tumor samples. Am J Pathol 1994; 145: 1301–8
   PubMed Web of Science ®Google Scholar
• Meuwissen M., van der Wal A. C., Koch K. T., van der Loos C. M., Chamuleau S. A., Teeling P., et al. Association between complex coronary artery stenosis and unstable angina and the extent of plaque inflammation. Am J Med 2003; 114: 521–7
   PubMed Web of Science ®Google Scholar
• Boekholdt S. M., Agema W. R., Peters R. J., Zwinderman A. H., van der Wall E. E., Reitsma P. H., et al. Variants of Toll‐like receptor 4 modify the efficacy of statin therapy and the risk of cardiovascular events. Circulation 2003; 107: 2416–21, Epub May 12 2003
   PubMed Web of Science ®Google Scholar
• Hollestelle S. C., De Vries M. R., Van Keulen J. K., Schoneveld A. H., Vink A., Strijder C. F., et al. Toll‐like receptor 4 is involved in outward arterial remodeling. Circulation 2004; 109: 393–8, Epub Dec 29 2003
   PubMed Web of Science ®Google Scholar
• Pasterkamp G., Smits P. C. Imaging of atherosclerosis. Remodelling of coronary arteries. J Cardiovasc Risk 2002; 9: 229–35
   PubMedGoogle Scholar
• Kol A., Sukhova G. K., Lichtman A. H., Libby P. Chlamydial heat shock protein 60 localizes in human atheroma and regulates macrophage tumor necrosis factor‐alpha and matrix metalloproteinase expression. Circulation 1998; 98: 300–7
   PubMed Web of Science ®Google Scholar
• Renko J., Kalela A., Jaakkola O., Laine S., Höyhtyä M., Alho H., et al. Serum matrix metalloproteinase‐9 is elevated in men with a history of myocardial infarction. Scand J Clin Lab Invest 2004; 64: 255–61
   PubMed Web of Science ®Google Scholar
• Corti R., Badimon J. J. Biologic aspects of vulnerable plaque. Curr Opin Cardiol 2002; 17: 616–25
   PubMed Web of Science ®Google Scholar
• Trask N., Califf R. M., Conley M. J., Kong Y., Peter R., Lee K. L., et al. Accuracy and interobserver variability of coronary cineangiography: a comparison with postmortem evaluation. J Am Coll Cardiol 1984; 3: 1145–54
   PubMed Web of Science ®Google Scholar
• Spiliopoulou C., Papadodima S., Kotakidis N., Koutselinis A. Clinical diagnoses and autopsy findings: a retrospective analysis of 252 cases in Greece. Arch Pathol Lab Med 2005; 129: 210–4
   PubMed Web of Science ®Google Scholar
• Schulte‐Altedorneburg G., Droste D. W., Kollar J., Beyna T., Felszeghy S., Modis L., et al. Measuring carotid artery stenosis: comparison of postmortem arteriograms with the planimetric gold standard. J Neurol 2005; 252: 575–82, Epub Mar 23 2005
   PubMed Web of Science ®Google Scholar