Advanced search
Publication Cover
Scandinavian Journal of Clinical and Laboratory Investigation Volume 80, 2020 - Issue 2
Submit an article Journal homepage
307
Views
8
CrossRef citations to date
0
Altmetric
Original Articles

Report of a new six-panel flow cytometry marker for early differential diagnosis of APL from HLA-DR negative Non-APL leukemia

Mohammad MoslehFaculty of Paramedical sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran; ;Rasad Pathobiology and Genetics Laboratory, Department of Flow Cytometry, Tehran, Iran;
,
Mahdieh MehrpouriRasad Pathobiology and Genetics Laboratory, Department of Flow Cytometry, Tehran, Iran;
,
Sasan GhaffariStudent Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran; ;Cell-based Therapies Research Center, Digestive Disease Research Institute, Tehran University of Medical Sciences, Tehran, Iran;
,
Zeinab SaeiDepartment of Flow Cytometry, Takhte Tavous Pathobiology Laboratory, Tehran, Iran;
,
Mahnaz AgaeipoorDepartment of Flow Cytometry, Takhte Tavous Pathobiology Laboratory, Tehran, Iran;
,
Farzaneh JadaliDepartment of Flow Cytometry, Takhte Tavous Pathobiology Laboratory, Tehran, Iran;
,
Esmaeil Shahabi SatlsarFaculty of Paramedical sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran; ;Department of Flow Cytometry, Takhte Tavous Pathobiology Laboratory, Tehran, Iran; Correspondence[email protected]
&
Roohollah GholampourTakhte Tavous Pathobiology LabCorrespondence[email protected]
 show all
Pages 87-92 | Received 29 Jun 2019, Accepted 28 Nov 2019, Published online: 12 Dec 2019

References

  • Estey EH. Acute myeloid leukemia: 2019 update on risk‐stratification and management. Am J Hematol. 2018;93(10):1267–1291.
  • Cerrano M, Itzykson R. New treatment options for acute myeloid leukemia in 2019. Curr Oncol Rep. 2019;21(2):16.
  • Welch JS, Ley TJ, Link DC, et al. The origin and evolution of mutations in acute myeloid leukemia. Cell. 2012;150(2):264–278.
  • Rowley J, Golomb H, Dougherty C. 15/17 translocation, a consistent chromosomal change in acute promyelocytic leukaemia. Lancet. 1977;309(8010):549–550.
  • de Thé H, Chomienne C, Lanotte M, et al. The t (15; 17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor α gene to a novel transcribed locus. Nature. 1990;347(6293):558.
  • Adams J, Nassiri M. Acute promyelocytic leukemia: a review and discussion of variant translocations. Arch Pathol Lab Med. 2015;139(10):1308–1313.
  • Choudhry A, DeLoughery TG. Bleeding and thrombosis in acute promyelocytic leukemia. Am J Hematol. 2012;87(6):596–603.
  • Degos L, Wang ZY. All trans retinoic acid in acute promyelocytic leukemia. Oncogene. 2001;20(49):7140.
  • Coombs C, Tavakkoli M, Tallman M. Acute promyelocytic leukemia: where did we start, where are we now, and the future. Blood Cancer J. 2015;5(4):e304.
  • Peters JM, Ansari MQ. Multiparameter flow cytometry in the diagnosis and management of acute leukemia. Arch Pathol Lab Med. 2011;135(1):44–54.
  • Dong HY, Kung JX, Bhardwaj V, et al. Flow cytometry rapidly identifies all acute promyelocytic leukemias with high specificity independent of underlying cytogenetic abnormalities. Am J Clin Pathol. 2011;135(1):76–84.
  • Vardiman JW, Harris NL, Brunning RD. The World Health Organization (WHO) classification of the myeloid neoplasms. Blood. 2002;100(7):2292–2302.
  • Gabert J, Beillard E, Van der Velden V, et al. Standardization and quality control studies of ‘real-time’quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia–a Europe Against Cancer program. Leukemia. 2003;17(12):2318.
  • Oelschlaegel U, Mohr B, Schaich M, et al. HLA‐DRneg patients without acute promyelocytic leukemia show distinct immunophenotypic, genetic, molecular, and cytomorphologic characteristics compared to acute promyelocytic leukemia. Cytometry B Cytometry. 2009;76:321–327.
  • Wetzler M, McElwain B, Stewart C, et al. HLA-DR antigen-negative acute myeloid leukemia. Leukemia. 2003;17(4):707.
  • Harani MS, Adil S, Shaikh MU, et al. Frequency of fab subtypes in acute myeloid leukemia patients at Aga Khan University Hospital Karachi. J Ayub Med Coll Abbottabad. 2005;17(1):26.
  • Callera F, Mulin CC, Rosa ES, et al. High prevalence of morphological subtype FAB M1 in adults with de novo acute myeloid leukemia in São José dos Campos, São Paulo. Sao Paulo Med J. 2006;124(1):45–47.
  • Fenu S, Carmini D, Mancini F, et al. Acute myeloid leukemias M2, potentially misdiagnosed as M3 variant French-American-Britain (FAB) subtype: a transitional form? Leuk Lymphoma. 1995;18(Sup1):49–55.
  • Xu F, Yin C-X, Wang C-L, et al. Immunophenotypes and immune markers associated with acute promyelocytic leukemia prognosis. Dis Markers. 2014;2014:1.
  • Liu M, Weng X, Gong S, et al. Flow cytometric analysis of CD64 expression pattern and density in the diagnosis of acute promyelocytic leukemia: a multi-center study in Shanghai, China. Oncotarget. 2017;8:80625.
  • Gorczyca W, Sun Z-Y, Cronin W, et al. Immunophenotypic pattern of myeloid populations by flow cytometry analysis. Methods Cell Biol. 2011;103:221–266.
  • Promsuwicha O, Auewarakul CU. Positive and negative predictive values of HLA-DR and CD34 in the diagnosis of acute promyelocytic leukemia and other types of acute myeloid leukemia with recurrent chromosomal translocations. Asian Pac J Allergy Immunol. 2009;27(4):209.
  • Ferrari A, Bussaglia E, Úbeda J, et al. Immunophenotype distinction between acute promyelocytic leukaemia and CD15− CD34− HLA‐DR − acute myeloid leukaemia with nucleophosmin mutations. Hematol Oncol. 2012;30(3):109–114.
  • Orfao A, Chillón MC, Bortoluci AM, et al. The flow cytometric pattern of CD34, CD15 and CD13 expression in acute myeloblastic leukemia is highly characteristic of the presence of PML-RARalpha gene rearrangements. Haematologica. 1999;84(5):405–412.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.