Circulating trefoil factors in relation to lung cancer, age and lung function: a cross-sectional study in patients referred for suspected lung cancer

References

• Kjellev S. The trefoil factor family – small peptides with multiple functionalities. Cell Mol Life Sci. 2009;66:1350–1369.
   PubMed Web of Science ®Google Scholar
• Busch M, Dunker N. Trefoil factor family peptides – friends or foes? Biomol Concepts. 2015;6:343–359.
   PubMedGoogle Scholar
• Braga Emidio N, Hoffmann W, Brierley SM, et al. Trefoil factor family: unresolved questions and clinical perspectives. Trends Biochem Sci. 2019;44:387–390.
   PubMed Web of Science ®Google Scholar
• Bade BC, Dela Cruz CS. Lung cancer 2020: epidemiology, etiology, and prevention. Clin Chest Med. 2020;41:1–24.
   PubMed Web of Science ®Google Scholar
• dos Santos Silva E, Ulrich M, Doring G, et al. Trefoil factor family domain peptides in the human respiratory tract. J Pathol. 2000;190:133–142.
   PubMed Web of Science ®Google Scholar
• Madsen J, Nielsen O, Tornoe I, et al. Tissue localization of human trefoil factors 1, 2, and 3. J Histochem Cytochem. 2007;55:505–513.
   PubMed Web of Science ®Google Scholar
• Wang XN, Wang SJ, Pandey V, et al. Trefoil factor 3 as a novel biomarker to distinguish between adenocarcinoma and squamous cell carcinoma. Medicine. 2015;94(20):e860.
   PubMed Web of Science ®Google Scholar
• Luo W, Tahara S, Kawasaki K, et al. The expression of trefoil factor 3 is related to histologic subtypes and invasiveness in lung adenocarcinoma. Oncol Lett. 2021;21(1):63.
   PubMed Web of Science ®Google Scholar
• Matsubara D, Yoshimoto T, Soda M, et al. Reciprocal expression of trefoil factor-1 and thyroid transcription factor-1 in lung adenocarcinomas. Cancer Sci. 2020;111:2183–2195.
   PubMed Web of Science ®Google Scholar
• Vestergaard EM, Borre M, Poulsen SS, et al. Plasma levels of trefoil factors are increased in patients with advanced prostate cancer. Clin Cancer Res. 2006;12:807–812.
   PubMed Web of Science ®Google Scholar
• Vestergaard EM, Brynskov J, Ejskjaer K, et al. Immunoassays of human trefoil factors 1 and 2: measured on serum from patients with inflammatory bowel disease. Scand J Clin Lab Invest. 2004;64(2):146–156.
   PubMed Web of Science ®Google Scholar
• Gronbaek H, Vestergaard EM, Hey H, et al. Serum trefoil factors in patients with inflammatory bowel disease. Digestion. 2006;74:33–39.
   PubMed Web of Science ®Google Scholar
• Samson MH. Quantitative measurements of trefoil factor family peptides: possibilities and pitfalls. Scand J Clin Lab Invest. 2013;73(3):193–202.
   PubMed Web of Science ®Google Scholar
• Zhang C, Xia R, Zhang B, et al. The predictive powers of plasma trefoil factor 3 or its related micro RNAs for patients with hepatocellular carcinoma. BMC Cancer. 2018;18(1):1110.
   PubMed Web of Science ®Google Scholar
• Jahan R, Ganguly K, Smith LM, et al. Trefoil factor(s) and CA19.9: a promising panel for early detection of pancreatic cancer. EBioMedicine. 2019;42:375–385.
   PubMed Web of Science ®Google Scholar
• Edfeldt K, Daskalakis K, Backlin C, et al. DcR3, TFF3, and Midkine are novel serum biomarkers in small intestinal neuroendocrine tumors. Neuroendocrinology. 2017;105(2):170–181.
   PubMed Web of Science ®Google Scholar
• Qu Y, Yang Y, Ma D, et al. Increased trefoil factor 3 levels in the serum of patients with three major histological subtypes of lung cancer. Oncol Rep. 2012;27(4):1277–1283.
   PubMed Web of Science ®Google Scholar
• Zhang M, Wang B, Chong QY, et al. A novel small-molecule inhibitor of trefoil factor 3 (TFF3) potentiates MEK1/2 inhibition in lung adenocarcinoma. Oncogenesis. 2019;8:65.
   PubMed Web of Science ®Google Scholar
• Viby NE, Nexo E, Kissow H, et al. Trefoil factors (TFFs) are increased in bronchioalveolar lavage fluid from patients with chronic obstructive lung disease (COPD). Peptides. 2015;63:90–105.
   PubMed Web of Science ®Google Scholar
• Viby NE, Pedersen L, Lund TK, et al. Trefoil factor peptides in serum and sputum from subjects with asthma and COPD. Clin Respir J. 2015;9(3):322–329.
   PubMed Web of Science ®Google Scholar
• Doubkova M, Karpisek M, Mazoch J, et al. Prognostic significance of surfactant protein A, surfactant protein D, Clara cell protein 16, S100 protein, trefoil factor 3, and prostatic secretory protein 94 in idiopathic pulmonary fibrosis, sarcoidosis, and chronic pulmonary obstructive disease. Sarcoidosis Vasc Diffuse Lung Dis. 2016;33:224–234.
   PubMed Web of Science ®Google Scholar
• Fu Y, Gaelings L, Jalovaara P, et al. Protein profiling of nasopharyngeal aspirates of hospitalized and outpatients revealed cytokines associated with severe influenza A(H1N1)pdm09 virus infections: a pilot study. Cytokine. 2016;86:10–14.
   PubMed Web of Science ®Google Scholar
• Lo-Bisgaard T, Espelund U, Frystyk J, et al. Vitamin B12 and its binding proteins in patients with non-small cell lung cancer referred to fast-track diagnostic work-up for lung cancer. Scand J Clin Lab Invest. 2020;80:14–19.
   PubMed Web of Science ®Google Scholar
• Espelund US, Bjerre M, Hjortebjerg R, et al. Insulin-like growth factor bioactivity, stanniocalcin-2, pregnancy-associated plasma protein-A, and IGF-binding protein-4 in pleural fluid and serum from patients with pulmonary disease. J Clin Endocrinol Metab. 2017;102:3526–3534.
   PubMed Web of Science ®Google Scholar
• Hjortebjerg R, Espelund U, Rasmussen TR, et al. Pregnancy-associated plasma protein-A2 is associated with mortality in patients with lung cancer. Front Endocrinol. 2020;11:614.
   PubMed Web of Science ®Google Scholar
• Vestergaard EM, Poulsen SS, Gronbaek H, et al. Development and evaluation of an ELISA for human trefoil factor 3. Clin Chem. 2002;48:1689–1695.
   PubMed Web of Science ®Google Scholar
• Celli BR, Wedzicha JA. Update on clinical aspects of chronic obstructive pulmonary disease. N Engl J Med. 2019;381:1257–1266.
   PubMed Web of Science ®Google Scholar
• Agusti A, Hogg JC. Update on the pathogenesis of chronic obstructive pulmonary disease. N Engl J Med. 2019;381:1248–1256.
   PubMed Web of Science ®Google Scholar