Strong ions and charge-balance

References

• Bevensee MO, Boron WF. Control of intracellular pH. In: RJ Alpern, OW Moe, and M Caplan, editors. Selding and giebisch’s the kidney. Edited by, Philadelphia, PA: Elsevier; 2013. 1773–1835.
   Google Scholar
• Weiner ID, Verlander JW. Renal acidification mechanisms. In: ASL Yu, GM Chertow, VA Luyckx, PA Marsden, K Skorecki, MW Taal. ‘brenner and rector’s the kidney. Philadelphia USA: Elsevier;2020. Chapter 9. 247–273.e11.
   Google Scholar
• Ring T, Nielsen S. Whole body acid-base modeling revisited. Am J Physiol Renal Physiol. 2017;312(4):F647–F653.
   PubMed Web of Science ®Google Scholar
• Lemann J, Jr, Bushinsky DA, Hamm LL. Bone buffering of acid and base in humans. Am J Physiol Renal Physiol. 2003;285(5):F811–F832.
   PubMed Web of Science ®Google Scholar
• Roos A, Boron WF. The buffer value of weak acids and bases: origin of the concept, and first mathematical derivation and application to physico-chemical systems. The work of M. Koppel and K. Spiro. Respir Physiol. 1980;40(1):1–32.
   PubMedGoogle Scholar
• DeLand EC. The classical structure of blood biochemistry – A mathematical model. The RAND Corporation. 1966;RM-4962-PR:1–124.
   Google Scholar
• Stewart PA. Modern quantitative acid-base chemistry. Can J Physiol Pharmacol. 1983;61(12):1444–1461.
   PubMed Web of Science ®Google Scholar
• Stewart PA. Independent and dependent variables of acid-base control. Respir Physiol. 1978;33(1):9–26.
   PubMedGoogle Scholar
• Lindinger MI, Heigenhauser GJF, McKelvie RS, et al. Blood ion regulation during repeated maximal exercise and recovery in humans. Am J Physiol. 1992;262(1 Pt 2):R126–R136.
   PubMedGoogle Scholar
• Adrogué HJ, Tucker BM, Madias NE. Clinical approach to assessing acid-base status: physiological vs Stewart. Adv Chronic Kidney Dis. 2022;29(4):343–354.
   PubMed Web of Science ®Google Scholar
• Herman DP, Booth KK, Parker OJ, et al. The pH of any mixture of monoprotic acids and bases. J Chem Educ. 1990;67(6):501–502.
   Web of Science ®Google Scholar
• Ring T, Kellum JA. Strong relationships in acid-base chemistry – modeling protons based on predictable concentrations of strong ions. PLOS One. 2016; 11(9):e0162872.
   PubMed Web of Science ®Google Scholar
• Ring T. Equilibrium and nonequilibrium pH. Am J Physiol Renal Physiol. 2010;298(2):F472–F473.
   PubMed Web of Science ®Google Scholar
• Ring T, Kellum JA. Modeling acid-base by minimizing charge-balance. ACS Omega. 2019;4(4):6521–6529.
   PubMed Web of Science ®Google Scholar
• Ring T, Rees SE, Frische S. Acid content and buffer-capacity: a charge-balance perspective. Scan J Clin Lab Invest. 2022;82(5):356–362.
   PubMed Web of Science ®Google Scholar
• Van Slyke D. On the measurement of buffer values and on the relationship of buffer value to the dissociation constant of the buffer and the concentration and reaction of the buffer solution. J Biol Chem. 1922;52(2):525–570.
   Google Scholar
• Kildeberg P. Acid-base status of biological fluids: amount of acid, kind of acid, anion-cation difference, and buffer value. Scand J Clin Lab Invest. 1983;43(2):103–109.
   PubMed Web of Science ®Google Scholar
• Occhipinti R, Boron WF. Mathematical modeling of acid-base physiology. Prog Biophys Mol Biol. 2015;117(1):43–58.
   PubMed Web of Science ®Google Scholar
• Ishida Y, Nayak S, Mindell JA, et al. A model of lysosomal pH regulation. J Gen Physiol. 2013;141(6):705–720.
   PubMed Web of Science ®Google Scholar
• Veshaguri S, Christensen SM, Kemmer GC, et al. Direct observation of proton pumping by a eukaryotic P-type ATPase. Science. 2016;351(6280):1469–1473.
   PubMed Web of Science ®Google Scholar
• Doberer D, Funk GC, Kirchner K, et al. A critique of Stewart’s approach: the chemical mechanism of dilutional acidosis. Intensive Care Med. 2009;35(12):2173–2180.
   PubMed Web of Science ®Google Scholar
• Andersen OS. The first dissociation exponent of carbonic acid as a function of pH. Scand J Clin Lab Invest. 1962;14:587–597.
   PubMed Web of Science ®Google Scholar
• Vaughan-Jones RD, Boron WF. Integration of acid-base disorders. N Engl J Med. 2015;372:389.
   PubMedGoogle Scholar
• Seifter JL. Integration of acid-base and electrolyte disorders. N Engl J Med. 2014;371(19):1821–1831.
   PubMed Web of Science ®Google Scholar
• Kurtz I, Kraut J, Ornekian V, et al. Acid-base analysis: a critique of the Stewart and bicarbonate-centered approaches. Am J Physiol Renal Physiol. 2008;294(5):F1009–F1031.
   PubMed Web of Science ®Google Scholar
• Nguyen MK, Kao L, Kurtz I. Calculation of equilibrium pH in a multiple-buffered aqueous solution based on partitioning of proton buffering: a new predictive formula. Am J Physiol Renal Physiol. 2009;296(6):F1521–F1529.
   PubMed Web of Science ®Google Scholar
• Bie P. Strong ion difference: questionable stewardship. Acta Physiologica. 2021;233(2):e13667.
   PubMed Web of Science ®Google Scholar
• Bie P. Strong ion difference: inconsistencies lining up. Acta Physiol. 2021;232(2):e13616.
   PubMed Web of Science ®Google Scholar
• Wright SH. Generation of resting membrane potential. Adv Physiol Educ. 2004;28(1-4):139–142.
   PubMed Web of Science ®Google Scholar
• Tinoco I, Sauer K, Wang JC. Physical chemistry: principles and applications in biological sciences. 3 ed,. New Jersey(NJ):Prentice-Hall; 1995 p 386.
   Google Scholar
• Rubin DM. Last word on viewpoint: Stewart’s approach to quantitative acid-base physiology should replace traditional bicarbonate-centered models. J Appl Physiol (1985). 2021;130(6):2024.
   PubMed Web of Science ®Google Scholar
• de Levie R. A pH centenary. Electrochim Acta. 2014;135:604–639.
   Web of Science ®Google Scholar
• Joutsuka T. Molecular mechanism of autodissociation in liquid water: ab initio molecular dynamics simulation. J Phys Chem B. 2022;126(24):4565–4571.
   PubMed Web of Science ®Google Scholar
• Kildeberg P. Quantitative acid-base physiology. New York USA: Odense University Press 1981.
   Google Scholar
• Siggaard-Andersen O, Fogh-Andersen N. Base excess or buffer base (strong ion difference) as measure of non-respiratory acid-base disturbance. Acta Anaestesiol Scand. 1995;39(Supplementum 106):123–128.
   Google Scholar
• Stone DK, Seldin DW, Kokko JP, et al. Anion dependency of rabbit medullary collecting duct acidification. J Clin Invest. 1983;71(5):1505–1508.
   PubMed Web of Science ®Google Scholar
• Henderson LJ. A critical study of the process of acid excretion. J Biol Chem. 1911;9(5):403–424.
   Google Scholar
• Brown JC, Packer RK, Knepper MA. Role of organic anions in renal response to dietary acid and base loads. Am J Physiol. 1989;257(2 Pt 2):F170–F176.
   PubMedGoogle Scholar
• Lemann J, Lennon EJ, Goodman AD, et al. The net balance of acid in subjects given large loads of acid or alkali. J Clin Invest. 1965;44(4):507–517.
   PubMed Web of Science ®Google Scholar
• Schwartz WB, Cohen JJ. The nature of the renal response to chronic disorders of acid-base equilibrium. Am J Med. 1978;64(3):417–428.
   PubMed Web of Science ®Google Scholar
• Kildeberg P, Engel K. A Physiological approach to acid-base diagnostics. National Bureau of Standard Special Publication 450. Proceedings of a workshop on pH and blood gases held at NBS, Gaithersburg, Maryland, July 7–81975. Issued 1977.
   Google Scholar