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Scandinavian Journal of Clinical and Laboratory Investigation Volume 43, 1983 - Issue 3
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Original Article

The chlorpropamide alcohol flush test in diabetes mellitus: Methods for objective evaluation

Peter Jerntorp Department of Medicine, University of Lund, Malmö General Hospital, Sweden
Pages 249-254 | Received 28 Sep 1982, Accepted 07 Jan 1983, Published online: 17 Mar 2010

References

  • Barnett A. H., Leslie R. D. G., Pyke D. A. Chlorpropamide-alcohol flushing and proteinuria in non-insulin-dependent diabetics. Br. Med. J. 1981; i: 522
  • Barnett A. H., Leslie R. D. G., Pyke D. A. Chlorpropamide-alcohol flushing and large-vessel disease in non-insulin-dependent diabetes. Br. Med. J. 1980; i: 261
  • Bertram F., Bendfeldt E., Otto H. Indikationen und Erfolge der peroralen Behandlung des Diabetes mellitus mit einem Sulfonylharn-stoffderivat. Dtsch. Med. Wschr. 1956; 81: 274
  • De Silva N. E., Tunbridge W. M. G., Alberti K. G. M. M. Low incidence of chlorpropamide-alcohol flushing in diet-treated, non-insulin-dependent diabetes. Lancet 1981; i: 128
  • Horrobin D. F., Manku M. S. Chlorpropamide/alcohol flushing and prostaglandins. Lancet 1980; i: 935
  • Jerntorp P., Almér L.-O. Chlorpropamide-alcohol flushing in relation to macro-angiopathy and peripheral neuropathy in non-insulin dependent diabetes. Acta med. Scand. 1981; 32(Suppl. 656)
  • Jerntorp P., Almér L.-O., Melander A. Is the blood chlorpropamide critical in chlorpropamide alcohol flush?. Lancet 1981; i: 165
  • Jerntorp P., Almér L.-O., Melander A. Chlorpropamide-induced inhibition of alcohol metabolism, the cause of CPAF. Diabetologia 1981; 21: 287
  • Jerntorp P., Öhlin H., Bergström B., Almér L.-O. Elevation of plasma acetaldehyde—the first step in CPAF?. Diabetologia 1980; 19: 286
  • Jerntorp P., Öhlin H., Bergström B., Almér L.-O. Increase in plasma acetaldehyde; an objective indicator of the chlorpropamide alcohol flush. Diabetes 1981; 30: 788
  • Karamanos B., Christacopoulos P., Kardoyannis Th., Tountas Ch., Komninos Z. Chlorpropamide-alcohol flushing (CPAF). Evaluation of criteria. Prevalence. Relation to metabolic parameters. Diabetologia 1981; 21: 289
  • Köbberling J., Bengsch N., Bruggeboes B., Schwarck H., Tillil H., Weber M. The chlorpropamide alcohol flush—lack of specificity for familial non-insulin dependent diabetes. Diabetologia 1980; 19: 359
  • Leslie R. D. G., Barnett A. H., Pyke D. A. Diabetic retinopathy and chlorpropamide alcohol flushing. Lancet 1979; i: 997
  • Leslie R. D. G., Pyke D. A. Chlorpropamide-alcohol flushing: a dominantly inherited trait associated with diabetes. Br. Med J. 1978; ii: 1519
  • Leslie R. D. G., Pyke D. A., Stubbs W. A. Sensitivity to enkephalin as a cause of non-insulin-dependent diabetes. Lancet 1979; i: 341
  • Lightman S. L., Summers M. C. Alterations in the activities of endogenous opiates by a metabolite of alcohol. J. Endocrin. 1980; 87: 38
  • Podgainy H., Bressler R. Biochemical basis of the sulfonylurea-induced Antabuse syndrome. Diabetes 1968; 17: 679
  • Radder J. K., Box M. C. J. G., Lemkes H. H. P. J. Facial skin temperature and the chlorpropamide/alcohol flush in diabetics. Lancet 1980; ii: 1037
  • Squadrito G., Cucinottta D., Mileto A., Intrieri F. Chlorpropamide alcohol flushing (CPAF) and diabetes mellitus in a Southern Italian population. Diabetologia 1981; 21: 82
  • Stowell A. R. An improved method for the determination of acetaldehyde in human blood with minimal ethanol interference. Clin. chim. Acta 1979; 98: 201
  • Strakosch C. R., Jefferys D. B., Keen H. Blockade of chlorpropamide alcohol flush by aspirin. Lancet 1980; i: 394

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