Non-invasive evaluation of bone formation: Measurements of serum alkaline phosphatase, whole body retention of diphosphonate and serum osteocalcin in metabolic bone disorders and thyroid disease

References

• Fogelman I. Skeletal uptake of diphosphonate: a review. Eur J Nucl Med 1980; 5: 473–6
   PubMedGoogle Scholar
• Fogelman I., Bessent R. G., Turner J. G., Citrin D. L., Boyle I. T., Greg W. R. The use of whole body retention of Tc-99m diphosphonate in the diagnosis of metabolic bone disease. J Nucl Med 1978; 19: 270–5
   PubMed Web of Science ®Google Scholar
• Caniggia A., Vattimo A. Kinetics of 99m-technetium-tin-methylcnc-diphosphonate in normal subjects and pathological conditions: a simple index of bone metabolism. Calcif Tissue Int 1980; 30: 5–13
   PubMed Web of Science ®Google Scholar
• Hyldstrup L., McNair P., Jensen G. F., Mogensen N. B., Transbøl I. Measurements of whole body retention of diphosphonate and other indices of bone metabolism in 125 normals: dependency on age sex and glomerular filtration. Scand J Clin Lab Invest 1984; 44: 673–8
   PubMed Web of Science ®Google Scholar
• Hyldstrup L., McNair P., Ring P., Henriksen O. Studies on diphosphonate kinetics (part I): evaluation of plasma elimination curves during 24 hours. Eur J Nucl Med 1987; 12: 581–4
   PubMedGoogle Scholar
• Hauschka P. V., Lian J. B., Gallop P. M. Direct identification of the calcium binding amino acid γ-carboxyglutamate in mineralized tissue. Proc Natl Acad Sci USA 1972; 72: 3925–9
   Web of Science ®Google Scholar
• Price P. A., Parthemore J. G., Deftos L. J. New biochemical marker for bone metabolism. Measurements by radioimmunoassay of bone Gla protein in plasma of normal subjects and patients with bone disease. J Clin Invest 1980; 66: 878–83
   PubMed Web of Science ®Google Scholar
• Brown J. P., Delmas P., Malaval C., Edouard M. C., Meunier P. J. Serum bone GLA-protein: a specific marker of bone formation in postmenopausal osteoporosis. 1984; i: 1091–3
   Google Scholar
• Transbøl I., Jørgensen F. S., Hornum I., Keiding N. Hypercalcaemia discrimination index: a multivariate analysis of parathyroid function in 107 hypercalcacmic patients. Acta Endocrinol (Copenh) 1977; 86: 768–83
   PubMedGoogle Scholar
• Committee of Enzymes of the Scandinavian Society of Clinical Chemistry and Clinical Physiology. Recommended methods for the determination of four enzymes in blood. Scand J Clin Lab Invest 1974; 33: 281–303
   Web of Science ®Google Scholar
• Hyldstrup L., Mogensen N., Jensen G. F., McNair P., Transbøl I. Urinary 99m-Tc-diphosphonate excretion as a simple method to quantify bone metabolism. Scand J Clin Lab Invest 1984; 44: 105–9
   PubMed Web of Science ®Google Scholar
• Hyldstrup L., McNair P., Transbøl I. GFR-corrected 24-hour whole body retention of diphosphonate: an improved index of bone metabolism. Scand J Clin Lab Invest 1988; 48: 341–345
   PubMed Web of Science ®Google Scholar
• Kampmann J. P., Siersbæk-Nielsen K., Kristensen M., Mølholm Hansen J. Variations in urinary creatinine and endogenous creatinine clearance due to age. Ugeskr Laeg 1971; 133: 2369–72
   PubMedGoogle Scholar
• Price P. A., Otsuka A. S., Poser J. W., Kristaponis J., Raman N. Characterization of a gamma-carboxyglutamic acid-containing protein from bone. Proc Natl Acad Sci USA 1976; 73: 1447–51
   PubMed Web of Science ®Google Scholar
• Harboe N., Ingild A. Immunization, isolation of immunoglobulins, estimation of antibody titer. Scand J Immunol (Suppl. 2) 1973; 1: 161–73
   Google Scholar
• Kyhse-Andersen J. Electroblotting of multiple gels: a simple apparatus without buffer tank for rapid transfer of proteins from polyacrylamide to nitrocellulose. J Biochcm Biophys Meth 1984; 10: 203–9
   PubMedGoogle Scholar
• Charles P., Poser J. W., Mosckilde L., Jensen F. T. Estimation of bone turnover by 47Ca-kinetics. J Clin Invest 1985; 76: 2254–8
   PubMed Web of Science ®Google Scholar
• Christiansen C., Rødbro P., Jensen H. Bone mineral content in the forearm measured by photon absorptiometry. Principles and reliability. Scand J Clin Lab Invest 1975; 35: 323–30
   PubMed Web of Science ®Google Scholar
• Bi Lund, Sørensen O. H. Measurements of 25-hydroxyvitamin D in serum and its relation to sunshine age and vitamin D intake in Danish population. Scand J Clin Lab Invest 1979; 39: 23–30
   PubMed Web of Science ®Google Scholar
• Bj Lund, Bi Lund, Sørensen O. H. Measurements of circulating 1,25-di-hydroxyvitamin D in man. Changes in serum concentrations during treatment with la-hydroxycholecalciferol. Acta Endocrinol (Copenh) 1979; 91: 338–50
   PubMedGoogle Scholar
• Delmas P. D., Warmer W. H., Mann K. G., Riggs B. L. Assessment of postmenopausal osteoporosis by measurements of serum bone Gla-protein. J Lab Clin Med 1983; 102: 470–6
   PubMed Web of Science ®Google Scholar
• Charles P., Mosekilde L., Jensen F. T. Primary hyperparathyroidism: evaluated by 47calcium kinetics calcium balance and serum bone-Gla-protein. Eur J Clin Invest 1986; 16: 277–83
   PubMed Web of Science ®Google Scholar
• Mosekilde L. Effects of thyroid hormone(s) on bone remodelling, bone mass and calcium-phosphorous homeostasis in man. Thesis. University of Aarhus. 1979
   Google Scholar
• Baley T. A., Harrison J. E., McNeill K. G., Mernagh J. R. Effect of thyrotoxicosis and its treatment on bone mineral and muscle mass. J Clin Endocrinol Metab 1980; 50: 916–22
   PubMed Web of Science ®Google Scholar
• Rasmussen H., Bordier P. The physiological and cellular basis of metabolic bone disease. Williams & Wilkins Co, Baltimore 1974; 192–200
   Google Scholar
• Cassar J., Joseph S. Alkaline phosphatase levels in thyroid disease. Clin Chim Acta 1969; 23: 33–7
   PubMed Web of Science ®Google Scholar
• Delmas P., Demiaux B., Malaval L., Chapuy M. C., Meunier P. J. Serum bone Gla-protein is not a sensitive marker of bone turnover in Paget's disease. Calcif Tissue Int 1986; 38: 60–1
   PubMed Web of Science ®Google Scholar
• Einhorn T. A., Vigorita V. J., Aaron A. Localization of Technetium-99m methylene diphosphonate in bone using microautoradiography. J Ortop Res 1986; 4: 180–7
   PubMed Web of Science ®Google Scholar
• Price P., Sloper S. A. Concurrent warfarin treatment further reduces bone mineral levels in 1,25-dihydroxyvitamin-D3 treated rats. J Biol Chem 1983; 258: 6004–7
   PubMed Web of Science ®Google Scholar