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Research Article

Fas/Fas Ligand Expression and Characteristics of Primed CD45RO+ T Cells in the Inflamed Mucosa of Ulcerative Colitis

Pages 1278-1283 | Published online: 08 Jul 2009

References

  • Elson CO, McCabe RP Jr. The immunology of inflammatory bowel disease. In: Kirsner JB, Shorter RG, editors. Inflammatory bowel disease. 4th ed. Baltimore (MD): Williams & Wilkins; 1995. p. 203–51.
  • Asakura H, Sugimura K. HLA, antineutrophil cytoplasmic autoantibody, and heterogeneity in ulcerative colitis. Gastroenterology 1995;108:597–9.
  • Allison MC, Poulter LW, Dhillon AP, Pounder RE. Immuno-histological studies of surface antigen on colonic lymphoid cells in normal and inflamed mucosa. Comparison of follicular and lamina propria lymphocytes. Gastroenterology 1990;99:421–30.
  • Schreiber S, MacDermott RP, Raedler A, Pinnau R, Bertovich MJ, Nash GS. Increased activation of isolated intestinal lamina propria mononuclear cells in inflammatory bowel disease. Gastroenterology 1991;101:1020–30.
  • Funakoshi K, Sugimura K, Anezaki K, Bannai H, Ishizuka K, Asakura H. Spectrum of cytokine gene expression in intestinal mucosal lesions of Crohn’s disease and ulcerative colitis. Digestion 1998;59:73–8.
  • Akbar AN, Borthwick N, Salmon M, Gombert W, Bofill M, Shamsadeen N, et al. The significance of low bcl-2 expression by CD45RO T cells in normal individuals and patients with acute viral infections. The role of apoptosis in T cell memory. J Exp Med 1993;178:427–38.
  • Benoist C, Mathis D. T-lymphocyte differentiation and biology. In: Paul WE, editor. Fundamental immunology. 4th ed. Philadelphia (PA): Lippincott-Raven; 1999. p. 367–409.
  • Brunner T, Mogil RJ, LaFace D, Yoo NJ, Mahboubi A, Echeverri F, et al. Cell-autonomous Fas (CD95)/Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature 1995;373:441–4.
  • Ju ST, Panka DJ, Cui H, Ettinger R, el-Khatib M, Sherr DH, et al. Fas (CD95)/FasL interactions required for programmed cell death after T-cell activation. Nature 1995;373: 444–8.
  • Salmon M, Pilling D, Borthwick NJ, Viner N, Janossy G, Bacon PA, et al. The progressive differentiation of primed T cells is associated with an increasing susceptibility to apoptosis. Eur J Immunol 1994;24:892–9.
  • Nagata S, Golstein P. The Fas death factor. Science 1995;267: 1449–56.
  • Dhein J, Walczak H, Baumler C, Debatin KM, Krammer PH. Autocrine T-cell suicide mediated by APO-1/. Nature 1995; 373:438–41.
  • Akbar AN, Terry L, Timms A, Beverley PC, Janossy G. Loss of CD45R and gain of UCHL1 reactivity is a feature of primed T cells. J Immunol 1988;140: 2171–8.
  • Nagata S, Suda T. Fas and Fas ligand: lpr and gld mutations. Immunol Today 1995;16:39–43.
  • Fuss IJ, Neurath M, Boirivant M, Klein JS, de la Motte C, Strong SA, et al. Related articles. Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn’s disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5. J Immunol 1996;157: 1261–70.
  • Mullin GE, Lazenby AJ, Harris ML, Bayless TM, James SP. Increased interleukin-2 messenger RNA in the intestinal mucosal lesions of Crohn’s disease but not ulcerative colitis. Gastroenterology 1992;102: 1620–7.
  • Breese E, Braegger CP, Corrigan CJ, Walker-Smith JA, MacDonald TT. Interleukin-2-and interferon-gamma-secreting T cells in normal and diseased human intestinal mucosa. Immunology 1993;78: 127–31.
  • Ueyama H, Kiyohara T, Sawada N, Isozaki K, Kitamura S, Kondo S, et al. High Fas ligand expression on lymphocytes in lesions of ulcerative colitis. Gut 1998;43:48–55.
  • Boirivant M, Marini M, Di Felice G, Pronio AM, Montesani C, Tersigni R, et al. Defective CD2 pathway-induced apoptosis. Gastroenterology 1999;116:557–65.
  • Truelove SC, Witts IJ. Cortisone in ulcerative colitis. Report on therapeutic trial. Br Med J 1955;2:1041–8.
  • Haruta J, Kusugami K, Kuroiwa A, Ina K, Shinoda M, Morise K, et al. Phenotypic and functional analysis of lamina propria mononuclear cells from colonoscopic biopsy specimens in patients with ulcerative colitis. Am J Gastroenterol 1992;87: 448–54.
  • Sato K, Kimura F, Nakamura Y, Murakami H, Yoshida M, Tanaka M, et al. An aggressive nasal lymphoma accompanied by high levels of soluble Fas ligand. Br J Haematol 1996; 94:379–82.
  • Gavrieli Y, Sherman Y, Ben-Sasson SA. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992;119:493–501.
  • Roman LI, Manzano L, De La Hera A, Abreu L, Rossi I, Alvarez-Mon M. Expanded CD4+ CD45RO+ phenotype and defective proliferative response in T lymphocytes from patients with Crohn’s disease. Gastroenterology 1996;110:1008–19.
  • Meenan J, Spaans J, Grool TA, Pals ST, Tytgat GN, van Deventer SJ. Altered expression of alpha 4 beta 7, a gut homing integrin, by circulating and mucosal T cells in colonic mucosal inflammation. Gut 1997;40: 241–6.
  • Schieferdecker HL, Ullrich R, Hirseland H, Zeitz M. T cell differentiation antigens on lymphocytes in the human intestinal lamina propria. J Immunol 1992;149:2816–22.
  • De Maria R, Boirivant M, Cifone MG, Roncaioli P, Hahne M, Tschopp J, et al. Functional expression of Fas and Fas ligand on human gut lamina propria T lymphocytes. A potential role for the acidic sphingomyelinase pathway in normal immunoregulation. J Clin Invest 1996;97:316–22.
  • Refaeli Y, Van Parijs L, London CA, Tschopp J, Abbas AK. Biochemical mechanisms of IL-2-regulated Fas-mediated T cell apoptosis. Immunity 1998;8:615–23.
  • Cheng J, Zhou T, Liu C, Shapiro JP, Brauer MJ, Kiefer MC, et al. Protection from Fas-mediated apoptosis by a soluble form of the Fas molecule. Science 1994;263:1759–62.
  • Tanaka M, Itai T, Adachi M, Nagata S. Downregulation of Fas ligand by shedding. Nat Med 1998;4:31–6.
  • Kusugami K, Matsuura T, West GA, Youngman KR, Rachmi-lewitz D, Fiocchi C. Loss of interleukin-2-producing intestinal CD4+ T cells in inflammatory bowel disease. Gastroenterology 1991;101: 1594–1605.
  • Manzano L, Alvarez-Mon M, Vargas JA, Giron JA, Abreu L, Fernandez-Corugedo A, et al. Deficient interleukin 2 dependent proliferation pathway in T lymphocytes from active and inactive ulcerative colitis patients. Gut 1994;35:955–60.
  • Salmon M, Scheel-Toellner D, Huissoon AP, Pilling D, Shamsadeen N, Hyde H, et al. Inhibition of T cell apoptosis in the rheumatoid synovium. J Clin Invest 1997;99:439–46.
  • Ma A. Fas and the immunologically underprivileged intestine. Gastroenterology 1997;113:345–8.
  • Di Sommam M, Somma F, Montani MS, Mangiacasale R, Cundari E, Piccolella E. TCR engagement regulates differential responsiveness of human memory T cells to Fas (CD95)-mediated apoptosis. J Immunol 1999;162:3851–8.
  • Maroto R, Shen X, Konig R. Requirement for efficient interactions between CD4 and MHC class II molecules for survival of resting CD4+ T lymphocytes in vivo and for activation-induced cell death. J Immunol 1999;162: 5973–80.
  • Bland P. MHC class II expression by the gut epithelium. Immunol Today 1988;9:174–8.
  • Iwamoto M, Koji T, Makiyama K, Kobayashi N, Nakane PK. Apoptosis of crypt epithelial cells in ulcerative colitis. J Pathol 1996;180:152–9.
  • Strater J, Wellisch I, Riedl S, Walczak H, Koretz K, Tandara A, et al. CD95 (APO-1/Fas)-mediated apoptosis in colon epithelial cells: a possible role in ulcerative colitis. Gastroenterology 1997;113:160–7.

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