- Monsen U, Brostrom O, Norden val 1 B, Sorstad J, Hellers G. Prevalence of inflammatory bowel disease among relatives of patients with ulcerative colitis. Scand J Gastroenterol 1987; 22:214-8.
- Orholm M, Munkholm P, Langholz E, Neilsen OH, Sorensen TIA, Binder V. Familial occurrence of inflammatory bowel disease. N Engl J Med 1991;324:84-8.
- Tysk C, Linberg E, Jamerot G, Floderus-Myrhed B. Ulcerative colitis and Crohn's disease in an unselected population of monozygotic and dizygotic twins: a study of heritability and the influence of smoking. Gut 1988;29:990-6.
- Monk M, Mendeloff AI, Siegel CI, Lilienfeld. An epidemiological study of ulcerative colitis and regional enteritis among adults in Baltimore; social and demographic factors. Gastroenterology 1969;56:847-57.
- Bernstein CN, Blanchard JF, Rawsthome P, Wajda A. Epidemiology of Crohn's disease and ulcerative colitis in a central Canadian province: a population based study. Am J Epidemiol 1999; 10;916-24.
- Cho JH, Brant SR. Genetics and genetic markers in inflammatory bowel disease. Curr Opin Gastroenterol 1998;14:283-8.
- Satsangi J, Parkes M, Louis E, Hashimoto L, Kato N, Welsh K. Two-stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3,7 and 12. Nature Genet 1996;14:199-202.
- Duerr RH, Barmada MM, Zhang L, Davis S, Preston RA, Chensny LJ. Linkage and association between inflammatory bowel disease and a locus on chromosome 12. Am J Human Genet 1998;63:95-100.
- Hugot JP, Laurent-Puig P, Gower-Rousseau C, Olsen JM, Lee JC, Beaugerie L. Mapping of a susceptibility locus for Crohn's disease on chromosome 16. Nature 1996;379:821-3.
- Ohmen JD, Yang H, Yamamoto KK, Zhao H, Ma Y, Bentley LG. Susceptibility locus for inflammatory bowel disease on chromosome 16 has a role in Crohn's disease, but not in ulcerative colitis. Human Molec Genet 1996;5:1679-83.
- Parkes M, Satsangi J, Lathrop GM, Bell JI, Jewell DP. Susceptibility loci in inflammatory bowel disease. Lancet 1996; 348:1588.
- Mirza MM, Lee J, Teare D, Hugot J, Laurent-Puig P, Colombel J. Evidence of linkage of the inflammatory bowel disease susceptibility locus on chromosome 16 (IBDl) to ulcerative colitis. J Med Genet 1998;35:218-21.
- Cho JH, Nicolae DL, Gold LH, Fields CT, LaBuda MC, Rohal PM. Identification of novel susceptibility loci for inflammatory bowel disease on chromosomes Ip, 3q, and 4q: evidence for epistasis between Ip and IBDl. Proc Natl Acad Sci 1998;95: 7502-7.
- Hampe J, Schreiber S, Shaw SH, Lau KF, Bridger S, Macpherson AJS. A genome-wide analysis provides evidence for novel linkages in inflammatory bowel disease in a large European cohort. Am J Hum Genet 1999;64:808-16.
- Purrmann J, Zeidler H, Bertrams J, JuIi E, Cleveland S, Beiges W. HLA antigens in ankylosing spondylitis associated with Crohn's disease. Increased frequency of the HLA phenotype B27, B44. J Rheumatol 1988;15:1658-61.
- Trachtenberg EA, Yang H, Hayes E, Vinson M, Lin C, Targan SR. HLA class II haplotype associations with inflammatory bowel disease in Jewish (Ashkenazi) abd bib-Jewish Caucasian populations. Human Immunol 2000;60:326-33.
- Kobayashi K,Atoh M, Konoeda Y, Yagita A Inoko H, dekigushi S. HLA, DQ and cell antigen receptor constant beta genes in Japenese patients with ulcerative colitis. Clin Exp. Immunol 1990;80:400-3.
- Dinnarello CA. Thompson RC. Blocking IL-I: interleukin 1 receptor antagonist in vivo and in vitro. Immunol Today 1991;12:404-10.
- Mansfield JC, Holden H. Tarlow JK, Di. Giovine FS, McDowell TL, Wilson AG. Novel genetic association baerween ulcerative colits and the anti-flammatory cytokine interleukin-1 receptor antogonist. Gastroenterologu 1994;106:637-42.
- Toutnas NA, Casini-Raggi V,Yang H, Di giovine FS, Vecchi M, Kam L. Functional and ethnic association of allele 2 of the interleukin-a1 receptor antagonist hene in ulcerative olitis. Gastroentrology 1999;117:806-13.
- Duerr Rh, Tran T. Association between ulcerative colitis and a polymorphism in intorn 2 of the interleukin-1 receptor antalogist gene (Abstract). Gastroenterology 1995;108:A812.
- Andus T, Ceasar I, Vogl D, Scholmerich J, Gross V. Association of HLA-DR15, P-ANCA and IL-I receptor antagonist allele 2 with ulcerative colitis (Abstract). Gastroenterology 1995;108: A770.
- Bloque G, Monteleone G, Crusius JBA, Dominianni A, Perrotti N, Kostense PJ. Further evidence for a genetic association of interleukin-1 receptor antagonist with ulcerative colitis in a northern and a Mediterranean population (Abstract). Gastroenterology 1995;108:A783.
- Bioque G, Bouma G, Bart J, Crusius A, Koutroubakis I, Kostense PJ. Evidence for genetic heterogeneity in IBD: the interleukin-1 receptor antagonist in the predispositio n to suffer from ulcerative colitis. Bur J Gastroenterol Hepatol 1996;8:105-10.
- Louis E, Satsangi J, Roussomoustakaki M, Parkes M, Fanning G, Welsh K. Cytokine gene polymorphisms in inflammatory bowel disease. Gut 1996;39:705-10.
- Hacker UT, Gomolka M, Keller E, Eigler A, Folwaczny C, Fricke H. Lack of association between an interleukin-1 receptor antagonist gene polymorphism and ulcerative colitis. Gut 1997; 40:623-7.
- Heresbach D, Alizadeh M, Dabadie A, Le Berre N, Colombel JF, Yaouanq J. Significance of interleukin- 1ß and interleukin-1 receptor antagonist genetic polymorphism in inflammatory bowel diseases. Am J Gastroenterol 1997;92:1164-9.
- Roussomoustakaki M, Satsangi J, Welsh K, Louis E, Fanning G, Targan S. Genetic markers may predict disease behaviour in patients with ulcerative colitis. Gastroenterology 1997;112: 1845-53.
- Stokkers PCF, van Aken BE, Basoski N, Reitsma PH, Tytgat GNJ, van Deventer SJH. Five genetic markers in the interleukin 1 family in relation to inflammatory bowel disease. Gut 1998; 43:33-9.
- Carter MJ, Jones S, Mansfield J, Di Giovine FS, Camp NJ, Lobo AJ. Further evidence of an association between allele 2 of the interleukin-1 receptor antagonist gene (IL-IRN) polymorphism and ulcerative colitis (Abstract). Gut 1998;42:W7.
Absence of a Genetic Association Between IL-1RN and IL-1B Gene Polymorphisms in Ulcerative Colitis and Crohn Disease in Multiple Populations from Northeast England
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