32
Views
12
CrossRef citations to date
0
Altmetric
Research Article

Relevance of Variants in Serum Antiproteinases for the Course of Chronic Pancreatitis

Pages 360-365 | Published online: 08 Jul 2009

  • Miller RR, Kuhlenschmidt MS, Coffee CJ, Kuo I, Glew RH. Comparison of the chemical. physical, and survival properties of normal and Z-variant alpha-1-antitrypsins. J Biol Chem 1976;251:4751-7.
  • Sottrup-Jensen L. Alpha-macroglobulins: structure, shape, andmechanism of proteinase complex formation. J Biol Chem 1989;264:11539-42.
  • Norman MR, Mowat AP, Hutchison DC. Molecular basis, clinical consequences and diagnosis of alpha-1 antitrypsin deficiency. Ann Clin Biochem 1997;34:230-46.
  • Barrett AJ, Starkey PM. The interaction of alpha 2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism. Biochem J 1973;133:709-24.
  • Blacker D, Wilcox MA, Laird NM, Rodes L, Horvath SM, Go RC, et al. Alpha-2 macroglobulin is genetically associated with Alzheimer disease. Nat Genet 1998;19:357-60.
  • Chu CT, Pizzo S. Biology of disease: a2-macroglobulin, complement and biologic defense: antigens, growth factors, microbial proteases and receptor ligation. Lab Invest 1994,71:792-812.
  • Norman JG, Fink G, Denham W, Yang J, Carter G, Sexton C, et al. Tissue-specific cytokine production during experimental acute pancreatitis. A probable mechanism for distant organ dysfunction. Dig Dis Sci 1997;42:1783-8.
  • Whitcomb DC, Gorry MC, Preston RA, Furey W, Sossenheimer MJ, Ulrich CD, et al. Hereditary pancreatitis is caused by a mutation in the cationic trypsinogen gene. Nat Genet 1996;14:141-5.
  • Gorry MC, Gabbaizedeh D, Furey W, Gates LK Jr, Preston RA, Aston CE, et al. Mutations in the cationic trypsinogen gene are associated with recurrent acute and chronic pancreatitis. Gastroenterology 1997;113:1063-8.
  • Witt H, Luck W, Becker M. A signal peptide cleavage site mutation the cationic t trypsinogen gene is strongly associated with chronic pancreatitis. Gastroenterology 1999;117:7-10.
  • Witt H, Luck W, Hennies HC, Classen M, Kage A, Lass U, et al. Mutations in the gene encoding the serine protease inhibitor, Kazal type 1 are associated with chronic pancreatitis. Nat Genet 2000;25:213-6.
  • Witt H, Luck W, Becker M, Böhmig M, Kage A, Truninger K, et al. Mutation in the SPINK 1 trypsin inhibitor gene, alcohol use, and chronic pancreatitis. JAMA 2001;285:2716-7.
  • Sahin-Toth M, Graf L, Toth M. Trypsinogen stabilization by mutation Arg 117 ? His: a unifying pathomechanism for hereditary pancreatitis? Biochem Biophys Res Commun 1999;264:505-8.
  • Sahin-Toth M. Human cationic trypsinogen. Role of Asn-21 in zymogen activation and implications in hereditary pancreatitis. J Biol Chem 2000;275:22750-5.
  • Bradley EL. A clinically based classification system for acute pancreatitis. Arch Surg 1993;128:586-90.
  • Cox DW, Johnson AM, Fagerhol MK. Report of Nomenclature Meeting for alpha 1-antitrypsin. INSERM. Rouen/Bois-Guillaume-1978. Hum Genet 1980;53:429-33.
  • Matthijs G, Marynen P. A deletion polymorphism in the human alpha-2- macroglobulin (A2M) gene. Nucleic Acids Res 1991;19:5102.
  • Teich N, Hoffmeister A, Keim V. Nomenclature of trypsinogen mutations in hereditary pancreatitis. Hum Mutat 2000;15:197-8.
  • Antonarakis SE. Recommendations for a nomenclature system for human gene mutations. Hum Mutat 1998;11:1-3.
  • Teich N, Mössner J, Keim V. Screening for mutations of the cationic trypsinogen gene: are they of relevance in chronic alcoholic pancreatitis? Gut 1999;44:413-6.
  • Teich N, Bauer N, Mössner J, Keim V. Mutational screening of patients with nonalcoholic chronic pancreatitis: identification of further trypsinogen variants. Am J Gastroenterol. In press.
  • Beneze K, Sabatke L, Fruhmann G. Alpha 1-antitrypsin: the PiMM subtypes. Do they play a role in development of chronic obstructive pulmonary diseases? Chest 1980;77:761-3.
  • Michalski JP, McCombs CC, Scopelitis E, Biundo JJ Jr, Medsger TA Jr. Alpha 1-antitrypsin phenotypes, including M subtypes, in pulmonary disease associated with rheumatoid arthritis and systemic sclerosis. Arthritis Rheum 1986;29:586-91.
  • Billingsley GD, Cox DW. Functional assay of alpha 1-antitrypsin in obstructive lung disease. Am Rev Respir Dis 1980;121:161-4.
  • Visser L, Blout ER. The use of p-nitropheny1 N-tert-butyloxycarbony1-L-alaninate as substrate for elastase. Biochim Biophys Acta 1972;268:257-60.
  • Beatty K, Travis J, Bieth J. The effect of alpha 2-macroglobulin on the interaction of alpha 1-proteinase inhibitor with porcine trypsin. Biochim Biophys Acta 1982;704:221-6.
  • Crystal RG, Brantly ML, Hubbard RC, Curiel DT, States DJ, Holmes MD. The alpha 1-antitrypsin gene and its mutations. Clinical consequences and strategies for therapy. Chest 1989;95:196-208.
  • Miszezuk-Jamska B, Guy O, Figarella C. Alpha 1-proteinase inhibitor in pure human pancreatic juice. Hoppe Seylers Z Physiol Chem 1983;364:509-13.
  • Novis BH, Young GO, Bank S, Marks IN. Chronic pancreatitis and alpha-1-antitrypsin. Lancet 1975;2:748-9.
  • Mihas AA, Hirschowitz BI. Alpha-1-antitrypsin and chronic pancretitis. Lancet 1976;2:1032-3.
  • Braxel C, Versieck J, Lemey G, Vanballenberghe L, Barbier F. Alpha 1-antitrypsin in pancreatitis. Digestion 1982;23:93-6.
  • Haber PS, Wilson JS, McGarity BH, Hall W, Thomas MC, Pirola RC. Alpha 1 antitrypsin phenotypes and alcoholic pancreatitis. Gut 1991;32:945-8.
  • Dow DJ, Lindsey N, Cairns NJ. Brayne C, Robinson D, Huppert FA, et al. Alpha-2 macroglobulin polymorphism and Alzheimer disease risk in the UK. Nat Genet 1999;22:16-7.
  • Rudrasingham V, Wavrant-De Vrieze F, Lambert JC, Chakraverty S, Kehoe P, Crook R, et al. Alpha-2 macroglobulin gene and Alzheimer disease. Nat Genet 1999;22:17-9.
  • Rogaeva EA, Premkumar S, Grubber J, Serneels L, Scott WK, Kawarai T, et al. An alpha-2 macroglobulin insertion-deletion polymorphism in Alzheimer disease. Nat Genet 1999;22:19-22.
  • Umans L, Serneels L, Overbergh L, Stas L, Van Leuven F. Alpha2-macroglobulin- and murinoglobulin-1-deficient mice. A mouse model for acute pancreatitis. Am J Pathol 1999;155:983-93.
  • Bagli M, Papassotiropoulos A, Jessen F, Schmitz S, Rao ML, Maier W, et al. Identical distribution of the alpha 2-macroglobulin pentanucleotide deletion in subjects with Alzheimer disease and controls in a German population. Am J Med Genet 2000;96:775-7.
  • Sodeyama N, Yamada M, Itoh Y, Suematsu N, Matsushita M, Otomo E, et al. Alpha2-macroglobulin polymorphism is not associated with AD or AD-type neuropathology in the Japanese. Neurology 2000;54:443-6.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.