Advanced search
Publication Cover
Scandinavian Journal of Gastroenterology Volume 38, 2003 - Issue 6
Submit an article Journal homepage
22
Views
7
CrossRef citations to date
0
Altmetric
Research Article

Progastrin and its Products from Patients with Chronic Viral Hepatitis and Liver Cirrhosis

Konturek S. J. Dept. of Physiology Medical College Jagiellonian University Kraków Poland
,
Gonciarz M. Dept. of Internal Medicine Silesian University Medical School Katowice Poland
,
Gonciarz Z. Dept. of Clinical Biochemistry Rigshospitalet University of Copenhagen Copenhagen Denmark
,
Bielanski W. Dept. of Physiology Medical College Jagiellonian University Kraków Poland
,
Mazur W. Dept. of Internal Medicine Silesian University Medical School Katowice Poland
,
Mularczyk A. Dept. of Clinical Biochemistry Rigshospitalet University of Copenhagen Copenhagen Denmark
,
Konturek P. C. Dept. of Physiology Medical College Jagiellonian University Kraków Poland
,
Goetze J. P. Dept. of Internal Medicine Silesian University Medical School Katowice Poland
&
Rehfeld J. F. Dept. of Clinical Biochemistry Rigshospitalet University of Copenhagen Copenhagen Denmark
 show all
Pages 643-647 | Published online: 08 Jul 2009

  • Dockray GJ, Varro A, Dimaline R, Wang T. The gastrins: their production and biological activities. Annu Rev Physiol 2001;G3: 119-39.
  • Lund T, Geurts van Kessel AH, Haun S, Dixon JE. The genes for human gastrin and cholecystokinin are located on different chromosomes. Hum Genet 1986;73:77-80.
  • Wiborg O, Berglund L, Boel E, Norris F, Norris K, Rehfeld JF, et al. Structure of human gastrin gene. Proc Natl Acad Sci USA 1984;81:1067-9.
  • Hilsted L, Rehfeld JF. Carboxyamidation of antrat progastrin: relation to other posttranslational modification. J Biol Chem 1987;262:16953-7.
  • Dickinson CJ, Yamada T. Gastrin-amidating enzyme in the porcine pituitary and antrum. Characterization of molecular forms and substrate specificity. J Biol Chem 1991;266:334-8.
  • Rehfeld JF, Johnsen AH. Identification of gastrin component I as gastrin 71, the largest possible bioactive progastrin product. Eur J Biochem 1994;223:765-8.
  • Rehfeld JF. Gastrins in serum. Scand J Gastroenterol 1973; 8: 577-83.
  • Nemeth J, Taylor B, Pauwels S, Varro A, Dockray GJ. Identification of progastrin derived peptides in colorectal carcinoma extracts. Gut 1993;34:90-5.
  • Ciccotosto GD, McLeish A, Hardy KJ, Shulkes A. Expression, processing and secretion of gastrin in patients with colorectal carcinoma. Gastroenterology 1995;109:1142-53.
  • Van Solinge WW, Nielsen FC, Friis-Hansen L, Falkmer UG, Rehfeld JF. Expression but incomplete maturation of progastrin in colorectal carcinomas. Gastroenterology 1993;104:1099-107.
  • Goetze JP, Nielsen FC, Burcharth F, Rehfeld JF. Closing the gastrin loop in pancreatic cancer. Cancer 2000;88:2487-94.
  • Caplin M, Khan K, Savage K, Rode J, Varrt A, Michaelis D, et al. Expression and processing of gastrin in hepatocellular carcinoma, fibrolamellar carcinoma and cholangio-carcinoma. J Hepatol 1999;30:519-26.
  • Siddheshwar RK, Gray JC, Kelly SD. Plasma levels of progastrin but not amidated gastrin and glycine extended gastrin are elevated in patients with colorectal carcinoma. Gut 2001;48: 47-52.
  • Konturek PC, Bielanski W, Konturek SJ, Hahn EG. Helicobacter pylori associated gastric pathology. J Physiol Pharmacol 1999;50:695-710.
  • Lauritsen KB, Rehfeld JF, Christiansen LA, Juhl E, Stadil F. Serum gastrin in cirrhosis. Scand J Gastroenterol 1976;! 1 Suppl 37:33-4.
  • Sato T, Imamura M, Sasaki I, Ohneda A. Gastric acid secretion and gastrin and gastric inhibitory polypeptide release in cirrhotic patients. Am J Gastroenterol 1985 ;80:163-9.
  • Langnas A, Shaw B. Surgical for hepatocellular carcinoma. In: Schiff E, Sorrell M, Maddrey W, editors. Schiffs Diseases of the Liver. Philadelphia and New York: Lippincot Raven; 1999. p. 1305-17.
  • Primigrani M, Carpinelli, Preatoni P. Natural history of portal hypertensive gastropathy in patients with liver cirrhosis. The New Italian Endoscopie Club for the study and treatment of esophageal varices (NIEC). Gastroenterology 2000; 19:181-7.
  • Konturek PC, Konturek SJ, Bielanski W, Karczewska E, Pierzchalski P, Duda A, et al. Role of gastrin in gastric cancerogenesis in Helicobacter pylori infected humans. J Physiol Pharmacol 1999;50:857-73.
  • Konturek JW, Bielanski W, Konturek SI. Eradication of Helicobacter pylori and gastrin-somatostatin link in duodenal ulcer patients. J Physiol Pharmacol 1996;47:161-76.
  • Rehfeld JF. A unique high-liter antiserum to gastrin. Scand J Clin Lab Invest 1981;41:723-7.
  • Daniel WW. Biostatistics. New York: Wiley and Sons; 1995.
  • Shigemori H, Iwno T, Ikegami M, Toyonaga A, Tanikawa K. Effects of propranolol on gastric mucosa perfusion and serum gastrin level in cirrhotic patients with portal hypertensive gastropathy. Dig Dis Sci 1994;39:2433-8.
  • Wang F, Leng X, Du R. The level of serum gastrin and ulceration in cirrhotic patients with portal hypertension. Zhonghua Wai Ke Za Zhi 1995;33:351-3.
  • Fraser AG, Pounder RE, Burroghs AK. Gastric secretion and peptic ulceration in cirrhosis. J Hepatol 1993;19:171-82.
  • Lam SK. Hypergastrinemia in cirrhosis of liver. Gut 1976; 17: 700-8.
  • Strunz UT, Thompson MR, Elashoff I, Grossman MI. Hepatic inactivation of gastritis of various lengths in dogs. Gastroenterology 1978;74:550-3.
  • Yao CZ, Bold RJ, Ishizuka J, Townsend CM, Jr, Thompson JC. Growth of mouse hepatocytes is stimulated by gastrin. J Cell Physiol 1995;163:532-7.
  • Watkins K, Curley S. Liver and bile ducts. In: Abelaff M, Armitage J, Lichter A, Niederhuber J, editors. Clinical Oncology. New York, Edinburgh, London, Madrid, Melbourne, San Francisco, Tokyo: Churchill Livingstone; 2000. p. 1681748.
  • Rocken C, Carl-McGrath S. Pathology and pathogenesis of hepatocellular carcinoma. Dig Dis Sci 2001;19:269-78.
  • Herold C, Reck T, Fischler P, Ott R, Radespiel-Troeger M, Gansimayer M, et al. Prognosis of a large cohort of patients with hepatocellular carcinoma in a single European center. Liver 2002;2223-8.
  • Ward J, Robinson PJ. How to detect hepatocellular carcinoma in cirrhosis. Eur Radiol 2002;12:2258-72.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Related research

People also read lists articles that other readers of this article have read.

Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.

Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.