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ORIGINAL ARTICLE

COX-1 and COX-2 conversely promote and suppress ischemia-reperfusion gastric injury in mice

, , , , , , , , , , , , & , PhD , MD show all
Pages 903-913 | Received 18 Oct 2004, Published online: 08 Jul 2009

References

  • Fukuse T, Hirata T, Omasa M, Wada H. Effect of adenosine triphosphate-sensitive potassium channel openers on lung preservation. Am J Respir Crit Care Med 2002; 165: 1511–5
  • Hamann GF, Liebetrau M, Martens H, Burggraf D, Kloss CU, Bultemeier G, et al. Microvascular basal lamina injury after experimental focal cerebral ischemia and reperfusion in the rat. J Cereb Blood Flow Metab 2002; 22: 526–33
  • Rossoni G, Muscara MN, Cirino G, Wallace JL. Inhibition of cyclo-oxygenase-2 exacerbates ischaemia-induced acute myocardial dysfunction in the rabbit. Br J Pharmacol 2002; 135: 1540–6
  • Kwiecien S, Brzozowski T, Konturek SJ. Effects of reactive oxygen species action on gastric mucosa in various models of mucosal injury. J Physiol Pharmacol 2002; 53: 39–50
  • Naito Y, Yoshikawa T, Kaneko T, Iinuma S, Nishimura S, Takahashi S, et al. Role of oxygen radicals in indomethacin-induced gastric mucosal microvascular injury in rats. J Clin Gastroenterol 1993; 17: S99–103
  • Kalia N, Bardhan KD. Of blood and guts: association between Helicobacter pylori and the gastric microcirculation. J Gastroenterol Hepatol 2003; 18: 1010–7
  • Kwiecien S, Brzozowski T, Konturek PC, Pawlik MW, Pawlik WW, Kwiecien N, et al. The role of reactive oxygen species and capsaicin-sensitive sensory nerves in the pathomechanisms of gastric ulcers induced by stress. J Physiol Pharmacol 2003; 54: 423–37
  • Burne MJ, Elghandour A, Haq M, Saba SR, Norman J, Condon T, et al. IL-1 and TNF independent pathways mediate ICAM-1/VCAM-1 up-regulation in ischemia reperfusion injury. J Leukoc Biol 2001; 70: 192–8
  • Kobayashi A, Imamura H, Isobe M, Matsuyama Y, Soeda J, Matsunaga K, et al. Mac-1 (CD11b/CD18) and intercellular adhesion molecule-1 in ischemia-reperfusion injury of rat liver. Am J Physiol Gastrointest Liver Physiol 2001; 281: G577–85
  • Bonder CS, Knight D, Hernandez-Saavedra D, McCord JM, Kubes P. Chimeric SOD2/3 inhibits at the endothelial-neutrophil interface to limit vascular dysfunction in ischemia-reperfusion. Am J Physiol Gastrointest Liver Physiol 2004; 287: G676–84
  • Miller TA. Protective effects of prostaglandins against gastric mucosal damage: current knowledge and proposed mechanisms. Am J Physiol 1983; 245: G601–G23
  • Kargman S, Charleson S, Cartwright M, Frank J, Riendeau D, Mancini J, et al. Characterization of prostaglandin G/H synthase 1 and 2 in rat, dog, monkey, and human gastrointestinal tracts. Gastroenterology 1996; 111: 445–54
  • Vane JR, Botting RM. New insights into the mode of action of anti-inflammatory drugs. Inflamm Res 1995; 44: 1–10
  • Mizuno H, Sakamoto C, Matsuda K, Wada K, Uchida T, Noguchi H, et al. Induction of cyclooxygenase 2 in gastric mucosal lesions and its inhibition by the specific antagonist delays healing in mice. Gastroenterology 1997; 112: 387–97
  • Gretzer B, Ehrlich K, Maricic N, Lambrecht N, Respondek M, Peskar BM. Selective cyclo-oxygenase-2 inhibitors and their influence on the protective effect of a mild irritant in the rat stomach. Br J Pharmacol 1998; 123: 927–35
  • Schmassmann A, Peskar BM, Stettler C, Netzer P, Stroff T, Flogerzi B, et al. Effects of inhibition of prostaglandin endoperoxide synthase-2 in chronic gastro-intestinal ulcer models in rats. Br J Pharmacol 1998; 123: 795–804
  • Futagami S, Hiratsuka T, Wada K, Tatsuguchi A, Tsukui T, Miyake K, et al. Inhibition of Helicobacter pylori-induced cyclo-oxygenase-2 aggravates NSAID-caused gastric damage in Mongolian gerbils. Aliment Pharmacol Ther 2002; 16: 847–55
  • Kishimoto Y, Wada K, Nakamoto K, Kawasaki H, Hasegawa J. Levels of cyclooxygenase-1 and -2 mRNA expression at various stages of acute gastric injury induced by ischemia-reperfusion in rats. Arch Biochem Biophys 1998; 352: 153–7
  • Maricic N, Ehrlich K, Gretzer B, Schuligoi R, Respondek M, Peskar BM. Selective cyclo-oxygenase-2 inhibitors aggravate ischaemia-reperfusion injury in the rat stomach. Br J Pharmacol 1999; 128: 1659–66
  • Morise Z, Komatsu S, Fuseler JW, Granger DN, Perry M, Issekutz AC, et al. ICAM-1 and P-selectin expression in a model of NSAID-induced gastropathy. Am J Physiol 1998; 274: G246–52
  • Iino T, Tashima K, Umeda M, Ogawa Y, Takeeda M, Takata K, et al. Effect of ellagic acid on gastric damage induced in ischemic rat stomachs following ammonia or reperfusion. Life Sci 2002; 70: 1139–50
  • Ogino K, Hobara T, Ishiyama H, Yamasaki K, Kobayashi H, Izumi Y, et al. Antiulcer mechanism of action of rebamipide, a novel antiulcer compound, on diethyldithiocarbamate-induced antral gastric ulcers in rats. Eur J Pharmacol 1992; 212: 9–13
  • Sigthorsson G, Simpson RJ, Walley M, Anthony A, Foster R, Hotz-Behoftsitz C, et al. COX-1 and 2, intestinal integrity, and pathogenesis of nonsteroidal anti-inflammatory drug enteropathy in mice. Gastroenterology 2002; 122: 1913–23
  • Krawisz JE, Sharon P, Stenson WF. Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Assessment of inflammation in rat and hamster models. Gastroenterology 1984; 87: 1344–50
  • Tepperman BL, Besco JM, Kiernan JA, Soper BD. Relationship between myeloperoxidase activity and the ontogenic response of rat gastric mucosa to ethanol. Can J Physiol Pharmacol 1991; 69: 1882–8
  • Chow JY, Ma L, Zhu M, Cho CH. The potentiating actions of cigarette smoking on ethanol-induced gastric mucosal damage in rats. Gastroenterology 1997; 113: 1188–97
  • Padol I, Huang JQ, Hunt RH. Anti-ulcerogenic properties of endothelin receptor antagonists in the rat. Aliment Pharmacol Ther 1999; 13: 537–44
  • Peterson GL. A simplification of the protein assay method of Lowry et al. which is more generally applicable. Anal Biochem 1987; 83: 346–56
  • Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979; 95: 351–8
  • Ferraz JG, Mcknight W, Sharkey KA, Wallace JL. Impaired vasodilatory responses in the gastric microcirculation of cirrhotic rats. Gastroenterology 1995; 108: 1183–91
  • Wallace JL, Mcknight W, Reuter BK, Vergnolle N. NSAID-induced gastric damage in rats: requirement for inhibition of both cyclooxygenase 1 and 2. Gastroenterology 2000; 119: 706–14
  • Bishop-Bailey D, Burke-Gaffney A, Hellewell PG, Pepper JR, Mitchell JA. Cyclo-oxygenase-2 regulates inducible ICAM-1 and VCAM-1 expression in human vascular smooth muscle cells. Biochem Biophys Res Commun 1998; 249: 44–7
  • Noguchi K, Iwasaki K, Ishikawa I. Prostaglandin F2 alpha upregulates intercellular adhesion molecule-1 expression in human gingival fibroblasts. J Periodontal Res 1999; 34: 277–81
  • Takeyama H, Tsukui T, Tatsuguchi A, Wada K, Miyake K, Shinoki K, et al. Non-steroidal anti-inflammatory drugs are not involved in ICAM-1 expression of endothelial cells but in that of gastric fibroblasts in vitro. J Tokyo Med Univ 2003; 61: 166–76
  • Perry MA, Wadhwa SS. Gradual reintroduction of oxygen reduces reperfusion injury in cat stomach. Am J Physiol 1988; 254: G366–G72
  • Camitta MG, Gabel SA, Chulada P, Bradbury JA, Langenbach R, Zeldin DC, et al. Cyclooxygenase-1 and -2 knockout mice demonstrate increased cardiac ischemia/reperfusion injury but are protected by acute preconditioning. Circulation 2001; 104: 2453–8
  • Kleine A, Kluge S, Peskar BM. Stimulation of prostaglandin biosynthesis mediates the gastroprotective effect of rebamipide in rats. Dig Dis Sci 1993; 38: 1441–9
  • Sun WH, Tsuji S, Tsujii M, Gunawan ES, Kawai N, Kimura A, et al. Induction of cyclooxygenase-2 in rat gastric mucosa by rebamipide, a mucoprotective agent. J Pharmacol Exp Ther 2000; 295: 447–52
  • Nagano C, Azuma A, Ishiyama H, Sekiguchi K, Imagawa K, Kikuchi M. Rebamipide suppresses formyl-methionyl-leucyl-phenylalanine (fMLP)-induced superoxide production by inhibiting fMLP-receptor binding in human neutrophils. J Pharmacol Exp Ther 2001; 297: 388–94

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