Risk factors for dyspepsia in a general population: Non-steroidal anti-inflammatory drugs, cigarette smoking and unemployment are more important than Helicobacter pylori infection

References

• Westbrook JI, McIntosh JH, Talley NJ. The impact of dyspepsia definition on prevalence estimates: considerations for future researchers. Scand J Gastroenterol 2000; 35: 227–33
   PubMed Web of Science ®Google Scholar
• van Bommel MJ, Numans ME, de Wit NJ, Stalman WA. Consultations and referrals for dyspepsia in general practice: a one-year database survey. Postgrad Med J 2001; 77: 514–8
   PubMed Web of Science ®Google Scholar
• Nyren O, Adami HO, Gustavsson S, Loof L. Excess sick-listing in nonulcer dyspepsia. J Clin Gastroenterol 1986; 82: 339–45
   Web of Science ®Google Scholar
• Lindell GH, Celebioglu F, Graffner HO. Non-ulcer dyspepsia in the long-term perspective. Eur J Gastroenterol Hepatol 1995; 7: 829–33
   PubMed Web of Science ®Google Scholar
• Enck P, Dubois D, Marquis P. Quality of life in patients with upper gastrointestinal symptoms: results from the Domestic/International Gastroenterology Surveillance Study (DIGEST). Scand J Gastroenterol 1999; Suppl 231: 48–54
   Web of Science ®Google Scholar
• Halder SL, Locke GR, III, Talley NJ, Fett SL, Zinsmeister AR, Melton LJ, III. Impact of functional gastrointestinal disorders on health-related quality of life: a population-based case-control study. Aliment Pharmacol Ther 2004; 19: 233–42
   PubMed Web of Science ®Google Scholar
• Koloski NA, Talley NJ, Boyce PM. The impact of functional gastrointestinal disorders on quality of life. Am J Gastroenterol 2000; 95: 67–71
   PubMed Web of Science ®Google Scholar
• Westbrook JI, Talley NJ, Westbrook MT. Gender differences in the symptoms and physical and mental well-being of dyspeptics: a population based study. Qual Life Res 2002; 11: 283–91
   PubMed Web of Science ®Google Scholar
• Voutilainen M, Mantynen T, Farkkila M, Juhola M, Sipponen P. Impact of non-steroidal anti-inflammatory drug and aspirin use on the prevalence of dyspepsia and uncomplicated peptic ulcer disease. Scand J Gastroenterol 2001; 36: 817–21
   PubMed Web of Science ®Google Scholar
• Holvoet J, Terriere L, Van Hee W, Verbist L, Fierens E, Hautekeete ML. Relation of upper gastrointestinal bleeding to non-steroidal anti-inflammatory drugs and aspirin: a case-control study. Gut 1991; 32: 730–4
   PubMed Web of Science ®Google Scholar
• Stanghellini V. Relationship between upper gastrointestinal symptoms and lifestyle, psychosocial factors and comorbidity in the general population: results from the Domestic/International Gastroenterology Surveillance Study (DIGEST). Scand J Gastroenterol 1999; Suppl 231: 29–37
   Google Scholar
• Penston JG, Pounder RE. A survey of dyspepsia in Great Britain. Aliment Pharmacol Ther 1996; 10: 83–9
   PubMed Web of Science ®Google Scholar
• Moayyedi P, Forman D, Braunholtz D, Feltbower R, Crocombc W, Liptrott M, et al. The proportion of upper gastrointestinal symptoms in the community associated with Helicobacter pylori, lifestyle factors, and nonsteroidal anti-inflammatory drugs. Leeds HELP Study Group. Am J Gastroenterol 2000; 95: 1448–55
   PubMed Web of Science ®Google Scholar
• Talley NJ, Zinsmeister AR, Schleck CD, Melton LJ, III. Smoking, alcohol, and analgesics in dyspepsia and among dyspepsia subgroups: lack of an association in a community. Gut 1994; 35: 619–24
   PubMed Web of Science ®Google Scholar
• Hopkins RJ, Girardi LS, Turney EA. Relationship between Helicobacter pylori eradication and reduced duodenal and gastric ulcer recurrence: a review. Gastroenterology 1996; 110: 1244–52
   PubMed Web of Science ®Google Scholar
• Agreus L, Engstrand L, Svardsudd K, Nyren O, Tibblin G. Helicobacter pylori seropositivity among Swedish adults with and without abdominal symptoms. A population-based epidemiologic study. Scand J Gastroenterol 1995; 30: 752–7
   PubMed Web of Science ®Google Scholar
• Bernersen B, Johnsen R, Bostad L, Straume B, Sommer AI, Burhol PG. Is Helicobacter pylori the cause of dyspepsia?. Br Med J 1992; 304: 1276–9
   PubMed Web of Science ®Google Scholar
• Rosenstock S, Kay L, Rosenstock C, Anderson LP, Bonnevie O, Jorgensen T. Relation between Helicobacter pylori infection and gastrointestinal symptoms and syndromes. Gut 1997; 41: 169–76
   PubMed Web of Science ®Google Scholar
• Stone MA, Barnett DB, Mayberry JF. Lack of correlation between self-reported symptoms of dyspepsia and infection with Helicobacter pylori, in a general population sample. Eur J Gastroenterol Hepatol 1998; 10: 301–4
   PubMed Web of Science ®Google Scholar
• Woodward M, Morrison CE, McColl KE. The prevalence of dyspepsia and use of antisecretory medication in North Glasgow: role of Helicobacter pylori vs. lifestyle factors. Aliment Pharmacol Ther 1999; 13: 1505–9
   PubMed Web of Science ®Google Scholar
• Bernersen B, Johnsen R, Straume B. Non-ulcer dyspepsia and peptic ulcer: the distribution in a population and their relation to risk factors. Gut 1996; 38: 822–5
   PubMed Web of Science ®Google Scholar
• Boekema PJ, van Dam van Isselt EF, Bots ML, Smout AJ. Functional bowel symptoms in a general Dutch population and associations with common stimulants. Neth J Med 2001; 59: 23–30
   PubMed Web of Science ®Google Scholar
• Bytzer P, Howell S, Leemon M, Young LJ, Jones MP, Talley LJ. Low socioeconomic class is a risk factor for upper and lower gastrointestinal symptoms: a population based study in 15,000 Australian adults. Gut 2001; 49: 66–72
   PubMed Web of Science ®Google Scholar
• Drossman DA, Li Z, Andruzzi E, Temple RD, Talley NJ, Thompson WG, et al. US householder survey of functional gastrointestinal disorders. Prevalence, sociodemography, and health impact. Dig Dis Sci 1993; 38: 1569–80
   PubMed Web of Science ®Google Scholar
• Stanghellini V. Three-month prevalence rates of gastrointestinal symptoms and the influence of demographic factors: results from the Domestic/International Gastroenterology Surveillance Study (DIGEST). Scand J Gastroenterol 1999; Suppl 231: 20–8
   Web of Science ®Google Scholar
• Wildner-Christensen M, Moller HJ, Schaffalitzky de Muckadell OB. Rates of dyspepsia one year after Helicobacter pylori screening and eradication in a Danish population. Gastroenterology 2003; 125: 372–9
   PubMed Web of Science ®Google Scholar
• Dimenas E, Glise H, Hallerback B, Hernqvist H, Svedlund J, Wiklund I. Quality of life in patients with upper gastrointestinal symptoms. An improved evaluation of treatment regimens?. Scand J Gastroenterol 1993; 28: 681–7
   PubMed Web of Science ®Google Scholar
• Svedlund J, Sjodin I, Dotevall G. GSRS: a clinical rating scale for gastrointestinal symptoms in patients with irritable bowel syndrome and peptic ulcer disease. Dig Dis Sci 1988; 33: 129–34
   PubMed Web of Science ®Google Scholar
• Dimenas E, Glise H, Hallerback B, Hernqvist H, Svedlund J, Wiklund I. Well-being and gastrointestinal symptoms among patients referred to endoscopy owing to suspected duodenal ulcer. Scand J Gastroenterol 1995; 30: 1046–52
   PubMed Web of Science ®Google Scholar
• Silva DS. Cancer prevention. Cancer epidemiology: principles and methods. WHO (IARC). 2002; 355–80
   Google Scholar
• Tabel: Befolkningen efter område, socioøkonomisk grp., herkomst, alder og køn (RAS11), Tabel: Folketal pr. 1. juli efter område, civilstand, alder og køn (BEF6). Danmarks Statistik 2002.
   Google Scholar
• Dimenas E, Carlsson G, Glise H, Israelsson B, Wiklund I. Relevance of norm values as part of the documentation of quality of life instruments for use in upper gastrointestinal disease. Scand J Gastroenterol 1996; Suppl 221: 8–13
   Web of Science ®Google Scholar
• Agreus L, Svardsudd K, Nyren O, Tibblin G. The epidemiology of abdominal symptoms: prevalence and demographic characteristics in a Swedish adult population. A report from the Abdominal Symptom Study. Scand J Gastroenterol 1994; 29: 102–9
   PubMed Web of Science ®Google Scholar
• Hollnagel H, Norrelund N, Larsen S. Gastrointestinal symptoms among 40-year-olds in Glostrup. An epidemiological study. Ugeskr Laeger 1982; 144: 267–73
   PubMedGoogle Scholar
• Kay L, Jorgensen T. Epidemiology of upper dyspepsia in a random population. Prevalence, incidence, natural history, and risk factors. Scand J Gastroenterol 1994; 29: 2–6
   PubMed Web of Science ®Google Scholar
• Colin-Jones DG. Management of dyspepsia: report of a working party. Lancet 1988; 12: 576–9
   Google Scholar
• Jones RH, Lydeard SE, Hobbs FD, Kenkre JE, Williams EL, Jones SJ, et al. Dyspepsia in England and Scotland. Gut 1990; 31: 401–5
   PubMed Web of Science ®Google Scholar
• Agreus L, Svardsudd K, Nyren O, Tibblin G. Irritable bowel syndrome and dyspepsia in the general population: overlap and lack of stability over time. Gastroenterology 1995; 109: 671–80
   PubMed Web of Science ®Google Scholar
• Talley NJ, Colin-Jones DG, Koch KL, Koch M, Nyren O, Stanghellini V. Functional dyspepsia: a classification with guidelines for diagnosis and management. Gastroeneterol Int 1991; 4: 145–60
   Google Scholar
• Talley NJ, Stanghellini V, Heading RC, Koch KL, Malagelada JR, Tytgat GN. Functional gastroduodenal disorders. Gut 1999; 45 Suppl 2: II37–II42
   PubMed Web of Science ®Google Scholar