277
Views
3
CrossRef citations to date
0
Altmetric
Original Article

MLLT10 promotes tumor migration, invasion, and metastasis in human colorectal cancer

, , , , , , , & show all
Pages 964-971 | Received 03 Apr 2018, Accepted 23 May 2018, Published online: 13 Aug 2018

References

  • Siegel RL, Miller KD, Fedewa SA, et al. Colorectal cancer statistics, 2017. Cancer J Clin. 2017;6;67:177–193.
  • Center MM, Jemal A, Smith RA, et al. Worldwide variations in colorectal cancer. Cancer J Clin. 2009;59:366–378.
  • Lao VV, Grady WM. Epigenetics and colorectal cancer. Nat Rev Gastroenterol Hepatol. 2011;8:686.
  • Yu BD, Hanson RD, Hess JL, et al. MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis. Proc Natl Acad Sci USA. 1998;195:10632–10636.
  • Ernst P, Fisher JK, Avery W, et al. Definitive hematopoiesis requires the mixed-lineage leukemia gene. Dev Cell. 2004;6:437–443.
  • Hess JL. Mechanisms of transformation by MLL. Crit Rev Eukaryot Gene Expr. 2004;14:235.
  • Ayton PM, Cleary ML. Molecular mechanisms of leukemogenesis mediated by MLL fusion proteins. Oncogene. 2001;20:5695.
  • Daser A, Rabbitts TH. Extending the repertoire of the mixed-lineage leukemia gene MLL in leukemogenesis. Genes Dev. 2004;18:965–974.
  • Bohlander SK, Muschinsky V, Schrader K, et al. Molecular analysis of the CALM/AF10 fusion: identical rearrangements in acute myeloid leukemia, acute lymphoblastic leukemia and malignant lymphoma patients. Leukemia. 2000;14:93.
  • Dreyling MH, Martinez-Climent JA, Zheng M, et al. The t (10; 11)(p13; q14) in the U937 cell line results in the fusion of the AF10 gene and CALM, encoding a new member of the AP-3 clathrin assembly protein family. Proc Natl Acad Sci USA. 1996;93:4804–4809.
  • Chaplin T, Bernard O, Beverloo HB, et al. The t(10;11) translocation in acute myeloid leukemia (M5) consistently fuses the leucine zipper motif of AF10 onto the HRX gene. Blood. 1995;86:2073–2076.
  • Chaplin T, Ayton P, Bernard OA, et al. A novel class of zinc finger/leucine zipper genes identified from the molecular cloning of the t (10; 11) translocation in acute leukemia. Blood. 1995;85:1435–1441.
  • Okada Y, Jiang Q, Lemieux M, et al. Leukaemic transformation by CALM-AF10 involves upregulation of Hoxa5 by hDOT1L. Nat Cell Biol. 2006;8:1017.
  • Okada Y, Feng Q, Lin Y, et al. hDOT1L links histone methylation to leukemogenesis. Cell. 2005;121:167–178.
  • Deshpande AJ, Rouhi A, Lin Y, et al. The clathrin-binding domain of CALM and the OM-LZ domain of AF10 are sufficient to induce acute myeloid leukemia in mice. Leukemia. 2011;25:1718.
  • Forissier S, Razanajaona D, Ay AS, et al. AF10-dependent transcription is enhanced by its interaction with FLRG. Biol Cell. 2007;99:563–571.
  • Maguer-Satta V, Rimokh R. FLRG, member of the follistatin family, a new player in hematopoiesis. Mol Cell Endocrinol. 2004;225:109–118.
  • Gómez-del Arco P, Koipally J, Georgopoulos K. Ikaros SUMOylation: switching out of repression. Mol Cell Biol. 2005;25:2688–2697.
  • Arco PG-D, Maki K, Georgopoulos K. Phosphorylation controls Ikaros's ability to negatively regulate the G1-S transition. Mol Cell Biol. 2004;24:2797–2807.
  • Mahmoudi T, Boj SF, Hatzis P, et al. The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis. PLoS Biol. 2010;8:e1000539.
  • Mohan M, Herz HM, Takahashi YH, et al. Linking H3K79 trimethylation to Wnt signaling through a novel Dot1-containing complex (DotCom). Genes Dev. 2010;24:574–589.
  • Dannenberg JH, Schuijff L, Dekker M, et al. Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130. Genes Dev. 2004;18:2952–2962.
  • Hammoud SS, Cairns BR, Jones DA. Epigenetic regulation of colon cancer and intestinal stem cells. Curr Opin Cell Biol. 2013;25:177–183.
  • Van Zijl F, Zulehner G, Petz M, et al. Epithelial–mesenchymal transition in hepatocellular carcinoma. Future Oncol. 2009;5:1169–1179.
  • Kokkinos MI, Wafai R, Wong MK, et al. Vimentin and epithelial-mesenchymal transition in human breast cancer – observations in vitro and in vivo. Cells Tissues Organs. 2007;185:191–203.
  • Satelli A, Li S. Vimentin in cancer and its potential as a molecular target for cancer therapy. Cell Mol Life Sci. 2011;68:3033–3046.
  • Lahat G, Zhu QS, Huang KL, et al. Vimentin is a novel anti-cancer therapeutic target; insights from in vitro and in vivo mice xenograft studies. PLoS One. 2010;5:e10105.
  • Hommura F, Furuuchi K, Yamazaki K, et al. Increased expression of β‐catenin predicts better prognosis in nonsmall cell lung carcinomas. Cancer. 2002;94:752–758.
  • Albelda SM. Role of integrins and other cell adhesion molecules in tumor progression and metastasis. Lab Invest. 1993;68:4–17.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.