56
Views
23
CrossRef citations to date
0
Altmetric
Research Article

The Effect of Bombesin, Cholecystokinin, Gastrin, and Their Antagonists on Proliferation of Pancreatic Cancer Cell Lines

Pages 1224-1229 | Published online: 08 Jul 2009

References

  • Johnson LR Physiology of the gastrointestinal tract. New York: Raven; 1994.
  • Huang S-C, Fortune KP, Wank SA, Kopin AS, Gardner JD. Multiple affinity states of different cholecystokinin receptors. J Biol Chem 1994;269:26121–6.
  • Jensen RT, Qian JM, Lin JT, Mantey SA, Pisegna JR, Wank SA. Distinguishing multiple CCK receptor subtypes. Studies with guinea pig chief cells and transfected human CCK receptor. Ann NY Acad Sci 1994;713:88–106.
  • Zhou W, Povosoki SP, Rosen NA, Longnecker DS, Bell RH Jr. Characterization of cholecystokinin receptors in rat pancreas. Ann NY Acad Sci 1994;713:331–3.
  • Ohlsson B, Axelson J, Sternby B, Rehfeld JF, Ihse I. Time- course of the pancreatic changes following long-term stimulation or inhibition of the CCK-A receptor. Int J Pancreatol 1995;18:59–66.
  • Monstein H-J, Nylander A-G, Salehi A, Chen D, Lundquist I, Håkansson R. Cholecystokinin-A and cholecystokinin-B/gastrin receptor mRNA expression in the gastrointestinal tract and pancreas of the rat and man. Scand J Gastroenterol 1996;31:383–90.
  • Smith JP, Liu G, Soundararajan V, McLaughlin PJ, Zagon IS. Identification and characterization of CCK-B/gastrin receptors in human pancreatic cancer cell lines. Am J Physiol 1994;266:R277–83.
  • Smith JP, Rickabaugh CA, McLaughlin PJ, Zagon IS. Cholecystokinin receptors and PANC-1 human pancreatic cancer cells. Am J Physiol 1993;265:G149–55.
  • Iwase K, Evers BM, Hellmich MR, Gou Y-S, Higashide S, Kim HJ, et al. Regulation of growth of human gastric cancer by gastrin and glycine-extended progastrin. Gastroenterology 1997;113:782–90.
  • Hoosein NM, Kiener PA, Curry RC, Rovati LC, McGilbra DK, Brattain MG. Antiproliferative effects of gastrin receptor antagonists and antibodies to gastrin on human colon carcinoma cell lines. Cancer Res 1998;48:7179–83.
  • Smith JP, Solomon TE, Bagheri S, Kramer S. Cholecystokinin stimulates growth of human pancreatic adenocarcinoma SW-1990. Dig Dis Sci 1990;35:1377–84.
  • Smith JP, Kramer ST, Solomon TE. CCK stimulates growth of six human pancreatic cancer cell lines in serum-free medium. Reg Pep 1991;32:341–9.
  • Smith Jp, Fantaskey AP, Liu G, Zagon IS. Identification of gastrin as a growth peptide in human pancreatic cancer. Am J Physiol 1995;268:R135–41.
  • Abbruzzese JL, Gholson CF, Daugherty K, Larson E, DuBrow R, Berlin R, et al. A pilot clinical trial of the cholecystokinin receptor antagonist MK-329 in patients with advanced pancreatic cancer. Pancreas 1992;7:165–71.
  • Shivaram S, Crist KA, Chaudhuri B, Mucci SJ, Chauduri PK. Effect of CCK receptor antagonist on growth of pancreatic adenocarcinoma. J Surg Res 1992;53:234–7.
  • Walsh JH. Bombesin/GRP peptides. In: Martin JB, Brownstein MJ, Kriegar DT, editors. Brain peptides update. New York: John Wiley; 1987. p. 193–214.
  • Lhoste E, Aprahamian M, Pousse A, Hoeltzel A, Stock-Damge C. Combined effect of chronic bombesin and secretin or cholecystokinin on the rat pancreas. Peptides 1985;6:83–7.
  • Hajri A, Balboni G, Koenig M, Garaud JC, Damage C. Gastrinreleasing peptide: in vivo and in vitro growth effects on an acinar pancreatic carcinoma. Cancer Res 1992;52:3726–32.
  • Hajri A, Koenig M, Balboni G, Damgé C. Expression and characterization of gastrin-releasing peptide receptor in normal and cancerous pancreas. Pancreas 1996;12:25–35.
  • Scudiero D, Schoemaker R, Paull K, Monks A, Tierney S, Nofziger T, et al. Evaluation of a soluble tetrazolium/formazan assay for cell growth and drug sensitivity in culture using human and other tumor cell lines. Cancer Res 1988;48:4827–33.
  • Song I, Brown DR, Wiltshire RN, Gantz I, Trent JM, Yamada T. The human gastrin/cholecystokinin type B receptor gene: alternative splice donor site in exon 4 generates two variant mRNAs. Proc Natl Acad Sci USA 1993;90:9085–9.
  • Monstein H-J, Nilsson I, Ellnebo-Svedlund K, Svensson SPS. Cloning and characterization of 5′-end alternatively spliced human cholecystokinin-B receptor mRNAs. Recept Channels 1998;6: 165–77.
  • Powers RE, Grady T, Orchard JL, Gilrane TB. Different effects of hyperstimulation by similiar classes of secretagogues on the exocrine pancreas. Pancreas 1993;8:58–63.
  • Thumwood CM, Hong J, Baldwin GS. Inhibition of cell proliferation by the cholecystokinin antagonist L-364,718. Exp Cell Res 1990;186: 15–21.
  • Smith JP, Kramer S, Bagheri S. Effects of a high-fat diet and L-364,718 on growth of human pancreas cancer. Dig Dis Sci 1990;35: 726–32.
  • Cantor P, Mortensen PE, Myhre J, Gjorup I, Worning H, Stahl E, et al. The effect of the cholecystokinin receptor antagonist MK-329 on meal-stimulated pancreaticobiliary output in humans. Gastroenterology 1992;102:1742–51.
  • Ohlsson B, Borg K, Rehfeld JF, Ihse I, Axelson J. The effect of intermittent injections of CCK-8S and the CCK-A receptor antagonist devazepide on cell proliferation in exocrine rat pancreas. Int J Pancreatol. 1998;24: 211–8.
  • Blackmore M, Hirst BH. Autocrine stimulation of growth of AR4–2J rat pancreatic tumour cells by gastrin. Br J Cancer 1992;66:32–8.
  • Smith JP, Shih A, Wu Y, McLaughlin PJ, Zagon IS. Gastrin regulates growth of human pancreatic cancer in a tonic and autocrine fashion. Am J Physiol 1996;270:R1078–84.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.