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Research Article

Nimesulide, a Selective Anti-Inflammatory Cyclooxygenase-2 Inhibitor, Does Not Affect Polyp Number and Mucosal Proliferation in Familial Adenomatous Polyposis

Page 1168 | Published online: 08 Jul 2009

References

  • Spagnesi MT, Tonelli F, Dolara P. Rectal proliferation and polyp occurrence in patients with familial adenomatous polyposis after sulindac treatment. Gastroenterology 1994;106:362–6.
  • Giardiello FM, Hamilton SR, Krush AJ. Treatment of colonic and rectal adenomas with sulindac in familial adenomatous polyposis. N Engl J Med 1993;328:1313–6.
  • Tonelli F, Valanzano R. Sulindac in familial adenomatous polyposis. Lancet 1993;342:1120.
  • Nakatsugi S, Fukutake M, Takahashi M. Suppression of intestinal polyp development by nimesulide, a selective cyclooxygenase-2 inhibitor in min mice. Jpn J Cancer Res 1997;88: 117–20.
  • Tavares IA, Bishai PM, Bennet A. Activity of nimesulide on costitutive and inducible cyclooxygenases. Arzneimittelforschung 1995;45:1093–5.

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