20
Views
6
CrossRef citations to date
0
Altmetric
Original Paper

Demonstration of Neutralizing Mucosal IgA Response to Intranasal HIV-1 env DNA Vaccines With or Without the V3 Glycosylation Site

, , , , &
Pages 360-364 | Received 16 Dec 2003, Accepted 05 Mar 2004, Published online: 08 Jul 2009

References

  • Liu MA. DNA vaccines: a review. J Intern Med 2003; 253: 402–10.
  • Robinson HL. New hope for an AIDS vaccine. Nat Rev Immunol 2002; 2: 239–50.
  • Ulmer JB. Influenza DNA vaccines, Vaccine 2002; 20 (Suppl 2): S74–6.
  • Hooper JW, Custer DM, Thompson E, Schmaljohn CS. DNA vaccination with the Hantaan virus M gene protects hamsters against 3 of 4 HFRS hantaviruses and elicits a high-titre neutralizing antibody response in Rhesus monkeys. J Virol 2001; 75: 8469–77.
  • Bernstein DI, Stanberry LR. Herpes simplex virus vaccines. Vaccine 1999; 17: 1681–9.
  • Corbet S, Vinner L, Hougaard DM, Bryder K, Nielsen HV, Nielsen C, Fomsgaard A. Construction, biological activity, and immunogenicity of synthetic envelope DNA vaccines based on a primary, CCR5-tropic, early HIV type 1 isolate (BX08) with human codons. AIDS Res Hum Retroviruses 2000; 16: 1997–2008.
  • Bolmstedt A, Hinkula J, Rowcliffe E, Biller M, Wahren B, Olofsson S. Enhanced immunogenicity of a human immunodeficiency virus type 1 env DNA vaccine by manipulating N-glycosylation signals. Effects of elimination of the V3 N306 glycan. Vaccine 2001; 20: 397–405.
  • Schønning K, Jansson B, Olofsson S, Nielsen J O, Hansen J S. Resistance to V3-directed neutralization caused by an N-linked oligosaccharide depends on the quartenary structure of the HIV-1 envelope oligomer. Virology 1996; 218: 134–40.
  • Bomsel M. Transcytosis of infectious human immunodeficiency virus a cross a tight human epithelial cell line barrier. Nat Med 1997; 3: 42–7.
  • Wahren B, Hinkula J, Stahle EL, Borrebaeck CA, Schwartz S, Wigzell H. Nucleic acid vaccination with HIV regulatory genes. Ann N Y Acad Sci 1995; 772: 278–81.
  • Ljungberg K, Rollman E, Erikson L, Hinkula J, Wahren B. Enhanced immune responses after DNA vaccination with combined envelope genes from different HIV-1 subtypes. Virology 2002; 302: 44–57.
  • Lundholm P, Asakura Y, Hinkula J, Lucht E, Wahren B. Induction of mucosal IgA by a novel jet delivery technique for HIV-1 DNA. Vaccine 1999; 17: 2036–42.
  • Åkerblom L, Hinkula J, Broliden PA, Mäkitalo B, Fridberger T, Rosen J, et al. Neutralizing cross-reactive and non-neutralizing monoclonal antibodies to HIV-1 gp120. Aids 1990; 4: 953–60.
  • Devito C, Levi M, Hinkula J, Fernandez Medina RD, Libonatti O, Wigzell H. Seroreactivity to HIV-1 V3 subtypes A to H peptides of Argentinian HIV-positive sera. J Acquired Immune Defic Syndr Hum Retroviruses 1998; 17: 156–9.
  • Kuiken C, Foley B, Hahn B, Marx P, McCutchan F, Mellors J, et al., eds. HIV Sequence Compendium 2002. Los Alamos: Los Alamos National Laboratory; 2001.
  • Yan H, Lamm ME, Bjorling E, Huang YT. Multiple functions of immunoglobulin A in mucosal defence against viruses: an in vitro measles virus model. J Virol 2002; 76: 10972–9.
  • Vinner L, Nielsen HV, Bryder K, Corbet S, Nielsen C, Fomsgaard A. Gene gun DNA vaccination with rev-independent synthetic HIV-1 gp160 envelope gene using mammalian codons. Vaccine 1999; 17: 2166–75.
  • Binley JM, Sanders RW, Clas B, Schuelke N, Master A, Guo Y, et al. A recombinant human immunodeficiency virus type 1 envelope glycoprotein complex stabilized by an intermolecular disulfide bond between the gp120 and gp41 subunits is an antigenic mimic of the trimeric virion- associated structure. J Virol 2000; 74: 627–43.
  • Earl PL, Sugiura W, Montefiori DC, Broder CC, Lee SA, Wild C, et al. Immunogenicity and protective efficacy of oligomeric human immunodeficiency virus type 1 gp140. J Virol 2001; 75: 645–53.
  • Schulke N, Vesanen MS, Sanders RW, Zhu P, Lu M, Anselma DJ, et al. Oligomeric and conformational properties of a proteolytically mature, disulfide-stabilized human immunodeficiency virus type 1 gp140 envelope glycoprotein. J Virol 2002; 76: 7760–76.
  • Yang X, Florin L, Farzan M, Kolchinsky P, Kwong PD, Sodroski J, Wyatt R. Modifications that stabilize human immunodeficiency virus envelope glycoprotein trimers in solution. J Virol 2000; 74: 4746–54.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.