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Research Article

Diagnosis and Clinical Presentation of Premalignant Lesions of the Penis

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Pages 201-214 | Published online: 09 Jul 2009

REFERENCES

  • Mant C, Cason J, Rice P, Best JM. Non-sexual transmission of cervical cancer-associated papilloma-viruses: an update. Papillomavirus Rep 2000; 11: 1–5.
  • Koutsky L. Epidemiology of genital human papilloma-virus infection. Am J Med 1997; 102: 3–8.
  • Bauer JIM, Hildesheim A, Schiffman MH, Glass AG, Rush BB, Scott DR, et al. Determinants of genital human papillomavirus infection in low-risk women in Portland, Oregon. Sex Transm Dis 1993; 20: 274–8.
  • Hildesheim A, Gravitt P. Schiffman MH, Kurman RJ, Barnes W, Jones S, et al. Determinants of genital human papillomavirus infection in low-income women in Washington, D.C. Sex Transm Dis 1993; 20: 280–5.
  • Hippeldinen M, Syrjänen S, Koskela H, Pulkkinen J, Saarikoski S, Syrjänen K. Prevalence and risk factors of genital human papillomavirus (HM) infections in healthy males: a study on Finnish conscripts. Sex Transm Dis 1993; 20: 321–8.
  • Wheeler CM, Parmenter CA, Hunt WC, Becker TM, Greer CE, Hildesheim A, et al. Determinants of genital human papillomavirus infection among cytologically normal women attending the University of New Mexico student health care center. Sex Transm Dis 1993; 20: 286–9.
  • van den Eeden SK, Babel L, Sherman KJ, McKnight B, Stergachis A, Daling JR. Risk factors for incident and recurrent condylomata acuminata among men. Sex Transm Dis 1998; 25: 278–84.
  • Babel LA, van den Eeden SK, Sherman KJ, McKnight B, Stergachis A, Daling JR. Risk factors for incident and recurrent condylomata acuminata among women. Sex Transm Dis 1998; 25: 285–91.
  • Kotloff KL, Wasserman SS, Russ K, Shapiro S, Daniel R, Brown W, et al. Detection of genital human papillomavirus and associated cytological abnormali-ties among college women. Sex Transm Dis 1998; 25: 243–50.
  • Hillman RJ, Ryait BK, Botcherby M, Walker MM, Taylor-Robinson D. Human papillomavirus DNA in the urogenital tracts of men with genital dermatoses: evidence for multifocal infection. Int J STD AIDS 1993; 4: 147–54.
  • Rymark P. Forslund O, Hansson BG, Lindholm K. Genital HPV infection not a local but a regional infection. Genitourin Med 1993; 69: 18–22.
  • Barrasso R, Gross GE. External genitalia: diagnosis. In: Gross GE, Barrasso R, eds. Human papillomavirus infection. A clinical atlas. Berlin: Ullstein Mosby, 1997: 289–361.
  • von Krogh G, Gross G, Barrasso R. Warts and HPV-related squamous cell tumours of the genitoanal area in adults; clinical presentation and evaluation. In: Gross G, von Krogh G, eds. Human papillomavirus infection in dermatovenereology. Boca Raton, FL: CRC Press, 1997: 259–304.
  • Wikström A, von Krogh G, Hedblad M-A, Syrjänen S. Papillomavirus-associated balanoposthitis. Genitourin Med 1994; 70: 175–81.
  • Rothman I, Berger RE, Kiviat N, Navarro AL, Remington ML. Urethral meatal warts in men: results of urethroscopy and biopsy. J Urol 1994; 151: 875–7.
  • Thin RN. Meatoscopy: an important technique for assessing meatal warts in men. Int J STD AIDS 1994; 5: 18–20.
  • Nathan PM, Thompson VC, Sharmacharja G, Hawks-well J, Fogarty B. A study of the prevalence of male intrameatal warts using meatoscopy in a genitourinary medicine department. Int J STD AIDS 1995; 6: 184–7.
  • Obalek S, Jablonska S, Beadenon S, Walczak L, Orth G. Bowenoid papulosis of the male and female geni-talia: risk of cervical neoplasia. J Am Acad Dermatol 1986; 14: 433–44.
  • Gimeno E, Vilata JJ, Sanchez IL, Lloret A, Fortea JM. Bowenoid papulosis: clinical and histological study of eight cases. Genitourin Med 1987; 63: 109–13.
  • Demeter LM, Stoler MH, Bonnez W, Corey L, Pappas P. Strussenberg J, et al. Penile intraepithelial neoplasia: clinical presentation and an analysis of the physical state of human papillomavirus DNA. J Infect Dis 1993; 168: 38–46.
  • Gross G, Hagedorn M, Ikenberg H, Rufli T, Dahlet C, Grosshans E, et al. Bowenoid papulosis. Presence of human papillomavirus (HET) structural antigens and of HPV 16-related DNA sequences. Arch Dermatol 1985; 121: 858–63.
  • Buschke A, Löwenstein LW. Ober carcinomähnliche Condylomata acuminata des Penis. KlM Woschr 1925; 4: 1726–35.
  • Knoblich R, Failing Jr JF. Giant condyloma acumina-tum (Buseke-Löwenstain tumor) of the rectum. Am J Clin Pathol 1967; 48: 389–95.
  • Bogomeletz WV, Potet F, Molas G. Condylomata acuminata, giant condyloma acuminatum (Buschke-Lowenstein tumor) and verrucous squamous carcinoma of the perianal and anorectal region: a continuous spectrum? Histopathology 1985; 9: 1155–60.
  • Mortensen PHG. The Buschke-Löwenstein tumor or verrucous carcinoma of the penis. Aust NZ J Surg 1987; 57: 337–41.
  • Dianzani C, Bucci M, Pierangeli A, Calvieri S, Degener AM. Association of human papillomavirus type 11 with carcinoma of the penis. Urology 1998; 51: 1046–8.
  • Cubilla AL, Barreto J, Caballero C, et al. Pathologic features of epidermoid cancer of the penis: a pros-pective study of 66 cases. Am J Surg Pathol 1993; 17: 753–63.
  • Cubilla AL, Barreto J, et al. The penis. In: Sternberg SS, ed. Diagnostic surgical pathology, 3rd edn., New York: Lippincott Raven, 1999: 2035–64.
  • Sanders CJG. Condylomata acuminata of the penis progressing rapidly to invasive squamous cell carcino-ma. Genitourin Med 1997; 73: 402–3.
  • Blessing K, McLaren K, Lessells A. Viral etiology for verrucous carcinoma. Histopathology 1986; 10: 1101–3.
  • Gregoire L, Cubilla AL, Reuter VE, Haas GP, Lan-caster WD. Preferential association of human papil-lomavirus with high-grade histologic variants of penile-invasive squamous cell carcinoma. J Natl Cancer Inst 1995; 87: 1705–9.
  • Kumar V, Collins T. Male genital tract. In: Robbin's pathologic basis of disease, 6th edn. Philadelphia, PA: W. B. Saunders, 1999: 1012–5.
  • Cubilla AL, Velaszques EF, Reuter VE, Olivia E, Mihm MC, Young RH. Warty (condylomatous) squamous cell carcinoma of the penis. A report of 11 cases and proposed calssification of "verruciform" penile tumors. Am J Surg Pathol 2000; 24: 505–12.
  • Barrasso R, DeBrux J, Croissant O, Orth G. High prevalence of papillomavirus-associated penile intra-epithelial neoplasia of the sexual partners of women with cervical intraepithelial neoplasia. N Engl J Med 1987; 317: 916–23.
  • Lloyd KM. Multicentric pigmented Bowen's disease of the groin. Arch Dermatol 1970; 101: 48–51.
  • Wade TR, Kopf AW, Ackerman AB. Bowenoid papu-losis of the genitalia. Arch Dermatol 1979; 115: 306–8.
  • Kaye V, Zhang J. Carcinoma in situ of penis: is distinction between erythroplasia of Queyrat and Bowen's disease relevant? Urology 1990; 36: 479–82.
  • Jaleel H, Narouz N, Wade AAH, Allan PS. Penile intraepithelial neoplasia-a veiled lesion on genitour-inary medicine. Sex Transm Infect 1999; 75: 435–6.
  • Wikström A, Hedblad M-A, Johansson B, Kalantari M, Syrjänen S, Lindberg M, et al. The acetic acid test in evaluation of subelinical genital papillomavirus infec-tion: A comparative study on penoscopy, histopathol-ogy, virology and scanning electron microscopy find-ings. Genitourin Med 1992; 68: 90–6.
  • Obalek S, Jablonska S, Beaudenon MB, Walczak L, Orth G. Bowenoid papulosis of the male and female genitalia: risk of cervical neoplasia. J Am Acad Dermatol 1986; 14: 433–40.
  • Patterson JVV, Kao GF, Graham JH, Helwig EB. Bowenoid papulosis: a clinicopathological study with ultrastructural observations. Cancer 1986; 57: 823–36.
  • Poblet E, Alfaro L, Femander-Segovia P. Jimenez-Reyes J, Salido EC. Human papillomavirus-associated penile squamous cell carcinoma in HIV-positive patients. Am J Surg Pathol 1999; 23: 1119–23.
  • Palefsky J. HPV-related disease in immunosuppressed individuals. In: Von Krogh G, Gross G, eds. Human papillomavirus infections in dermatovenereology. Boca Raton, FL: CRC Press, 1997: 227–40.
  • Sufrin G, Hubem R. Benign and malignant lesions of the penis. In: Gillenwater JY, et al, eds. Adult and pediatric urology, 2nd edn. Chicago, IL: Year Book Medical Publishers, 1991: 1643–81.
  • Bowen JT. Precancerous dermatoses: a study of two cases of chronic atypical epithelial proliferation. J Cutan Dis 1912; 30: 244–59.
  • Queyrat L. Erythroplasie du gland. Bull Soc Fr Dermatol Syphilogr 1911; 22: 378–82.
  • Michail GR. Cancers, precancers, and pseudocancers on the male genitalia: a review of clinical appearances, histopathology, and management. J Dermatol Surg Oncol 1980; 6: 1027–35.
  • Park KS, Kim KH, Youn S-W, Hwang J-H, Park K-H, Alm J-S, et al. Heterogeneity of human papillomavirus DNA in a patient with Bowenoid papulosis that progressed to squamous cell carcinoma. Br J Dermatol 1999; 139: 1087–91.
  • Raghavaiah NV, Soloway MS, Murphy WM. Malignant penile horn. J Urol 1997; 118: 1068–9.
  • Graham JH, Helwig EB. Erythroplasia of Queyrat: a clinicopathologic and histochemical study. Cancer 1973; 32: 1396–414.
  • Jaeger AB, Gramkow A, Melbye H, Frisch M. Bowen disease and risk of subsequent malignant neoplasms: a population-based cohort study in 1147 patients. Arch Dermatol 1999; 135: 790–3.
  • Jensen MS. Cancer of the penis in Denmark 1942 to 1962 (511 cases). Dan Med Bull 1977; 24: 66–72.
  • Fernando JJR, Wanas TM. Squamous cell carcinoma of the penis and previous recurrent balanitis: a case report. Genitourin Med 1991; 67: 153–5.
  • Young MJ, Reda DJ, Waters WB. Penile carcinoma: a twenty-five-year experience. Urology 1991; 38: 529–32.
  • Edwards S. Balanitis and balanoposthitis: a review. Genitourin Med 1996; 72: 155–9.
  • English JC, Laws RA, Keough GC, et al. Dermatoses of the glans penis and prepuce. J Am Acad Dermatol 1997; 37: 1–24.
  • Tan SH, Derick E, McKee PH, et al. Altered p53 expression and epidermal cell proliferation is seen in vulval lichen sclerosus. J Cutan Pathol 1994; 21: 316–23.
  • Levi JE, Rahal P. Sarkis AS, Villa LL. Human papillomavirus DNA and p53 status in penile carcino-mas. Int J Cancer 1998; 76: 779–83.
  • Maden C, Sherman KJ, Beckmann AM, Hislop TG, Teh CZ, Ashley RL, et al. History of circumcision, medical conditions, and sexual activity and risk of penile cancer. J Natl Cancer Inst 1993; 85: 19–24.
  • Moses S, Bailey RC, Ronald AR. Male circumcision: assessment of health benefits and risks. Sex Transm Infect 1998; 74: 368–73.
  • Mallou E, Hawkins D, Dinneen M, Francis N, Fearfield, Newson P, et al. Circumcision and genital dermatosis. Arch Dermatol 2000; 136: 350–9.
  • Hemal AK, Kumar R, Wadhwa SN. Carcinoma of the penis in a young boy. A case report. Indian J Cancer 1996; 33: 108–10.
  • Ross BS, Levine VL, Dickson C, Ashinoff R. Squamous cell carcinoma of the penis in a circumcised man: a case for dermatology and urology and review of the literature. Cutis 1998; 61: 41–3.
  • Meffert JJ, Davis BM, Grimwood RJ J Am Acad Dematol 1995; 32: 393–416.
  • Thomas RHM, McGibbon DH, Black MMM. Lichen sclerosus et atrophicus and autoimmunity-a study of 350 women. Br J Dermatol 1988; 118: 41–6.
  • Oikarinen A, Sandberg M, et al. Collagen biosynthesis in lichen sclerosus et atrophicus studied by biochemical and in situ hybridization techniques. Acta Dermatove-nerol 1991; (Suppl 162): 3–12.
  • Carli P. Moretti S, et al. Fibrogenic cytokines in vulvar lichen sclerosus. J Reprod Med 1997; 42: 161–5.
  • Meyrick Thomas RH, Ridley CM, Black MM. Clinical features and therapy of lichen sclerosus et atrophicus affecting males. Clin Exp Dermatol 1987; 12: 126–8.
  • Tompkins KJ, James WD. Persistent bullae on the penis of an elderly man. Arch Dermatol 1987; 123: 1392, 1394–5.
  • Estcourt CS, Higgins SP, Goomey BP. Recurrent bullous balanitis: an unusual presentation of balanitis xerotica obliterans. Int J STD AIDS 1994; 5: 58–9.
  • Mikat DM, Ackerman HR, Mikat KW. Balanitis xerotica obliterans: report of a case in a 11-year-old and review of the literature. Pediatrics 1973; 52: 25–8.
  • Bainbridge DR, Whitaker RH, Shepheard BGF. Bala-nitis xerotica obliterans and urinary obstruction. Br J Urol 1971; 43: 487–91.
  • Staff WG. Urethral involvement in balanitis xerotica obliterans. Br J Urol 1970; 47: 234–9.
  • Hawksell J, Nathan M. Lichen sclerosus and acute urinary obstruction. Genitourin Med 1992; 68: 177–8.
  • Chalmers RJG, Burton PA, Bennett RF, Goring CC, Smith JB. Lichen sclerosus et atrophicus. A common and distinctive cause of phimosis in boys. Arch Dermatol 1984; 120: 1025–7.
  • Ledwig PA, Weigland DA. Late circumcision and lichen sclerosus et atrophicus of the penis. J Am Acad Dermatol 1989; 20: 211–4.
  • Bale PM, Martin HCO. Balanitis xerotica obliterans in children. Pediatr Pathol 1987; 7: 617–7.
  • Aynaud O, Piron D, Casanomva J-M. Incidence of preputial lichen sclerosus in adults: histologic study of circumcision specimens. J Am Acad Dermatol 1999; 41: 923–6.
  • Dahlman-Gihgozlan K, Hedblad M-A, von Krogh G. Penile lichen sclerosus et atrophicus treated with clobetasol diproprionate O.05% cream: A retrospective clinical and histopathologic study. J Am Acad Dermatol 1999; 40: 451–7.
  • Schinella RA, Miranda D. Posthitis xerotica obliterans in circumcision specimens. Urology 1974; 111: 349–51.
  • Rickwood AMK, Hemalatha V, Batcup G, et al. Phimosis in boys. Br J Urol 1980; 52: 147–50.
  • Campus GV, Ena P. Schuderi N. Surgical treatment of balanitis xerotica obliterans. Plast Reconstr Surg 1984; 73: 652–7.
  • Chalmers RJG, Burton PA, Bennett RF, et al. Lichen sclerosus et atrophicus: a common and distinctive cause of phimosis in boys. Arch Dermatol 1984; 120: 1025–7.
  • Garat JM, Chechile G, Algaba F, et al. Balanitis xerotica obliterans in children. J Urol 1986; 136: 436–7.
  • Clemmensen OJ, Krogh J, Petri M. The histologic spectrum of prepuces from patients with phimosis. Am J Dermatopathol 1988; 10: 10–6.
  • Loening-Bauke V. Lichen sclerosus et atrophicus in children. Am J Dis Child 1991; 145: 1058–61.
  • Ridley CM. Genital lichen sclerosus (lichen sclerosus et atrophicus) in childhood and adolescence. J R Soc Med 1993; 86: 69–75.
  • Carli P. Cattaneo A, De Magnis A, Biggeri A, Taddei G, Gianotti B. Squamous cell carcinoma arising in vulvar lichen sclerosus: a longitudinal cohort study. Eur J Cancer Prey 1995; 4: 491–5.
  • Walkden V, Chia Y, Wojnarowska F. The association of squamous cell carcinoma of the vulva and lichen sclerosus: implications for follow-up. J Obstet Gyaecol 1997; 17: 551–3.
  • Bart RS, Kopf AW. Squamous-cell carcinoma arising in balanitis xerotica obliterans. J Dermatol Surg Oncol 1978; 4: 556–8.
  • Campus G-V, Alla F, Bosincu L. Squamous cell carcinoma and lichen sclerosus et atrophicus of the prepuce. Plast Reconstr Surg 1992; 89: 962–4.
  • Bingham JS. Carcinoma of the penis developing in lichen sclerosus et atrophicus. Br J Venereol Dis 1978; 54: 350–1.
  • Weigland DA. Lichen sclerosus et atrophicus, multiple dysplastic keratoses, and squamous cell carcinoma of the glans penis. J Dermatol Surg Oncol 1980; 6: 45–61.
  • Jamieson NV, Bullock KN, Barker THVV. Adenosqua-mous carcinoma of the penis associated with balanitis xerotica obliterans. Br J Urol 1986; 58: 730–1.
  • Weber P. Rabinovitz H, Garland L. Verrucous carci-noma in penile lichen sclerosus et atrophicus. J Dermatol Surg Oncol 1987; 13: 529–32.
  • Ledwig PA, Weigland DA. Late circumcision and lichen sclerosus et atrophicus of the penis. J Am Acad Dermatol 1989; 20: 211–4.
  • Dore B, Irani J, Aubert J. Carcinoma of the penis and lichen sclerosus et atrophicus: a case report. Eur Urol 1990; 18: 153–5.
  • Pride HB, Miller F, Tyler WB. Penile squamous cell carcinoma arising from balanitis obliterans. J Am Acad Dermatol 1993; 29: 469–73.
  • Simonart T, Noel JC, De Dobbeleer G, Simonart JM. Carcinoma of the glans penis arising 20 years after lichen sclerosus. Dermatology 1997; 196: 337–8.
  • Lau PWY, Cook N, Andrews H, Bracka A, Myint SH. Detection of human papillomavirus types in balanitis xerotica obliterans and other penile conditions. Geni-tourin Med 1995; 71: 228–30.
  • Leibowitch M, Neil S, Pelisse M, et al. The epithelial changes associated with squamous cell carcinoma of the vulva: a review of the clinical, histological and virological findings in 78 women. Br J Obstet Gynaecol 1990; 97: 1135–9.
  • Hording U, Junge J, Daugaard S, Lundvall F, Poulsen H, Bock JE. Vulvar squamous cell carcinoma and papillomaviruses: indications for two different etiolo-gies. Gynecol Oncol 1994; 52: 241–6.
  • Wilmer C, Cavelier-Balloy B, Nogues C, Trassard M, Le Dousall V. Analysis of alterations adjacent to invasive vulvar carcinoma and their relationship with the associated carcinoma: a study of 67 cases. Eur J Gynaecol Oncol 1998; 19: 25–31.
  • Powell JJ, Wojanorwska F. Lichen sclerosus. Lancet 1999; 353: 1777–83.
  • Scurry J. Does lichen sclerosus play a central role in the pathogenesis of human papillomavirus negative vulvar squamous cell carcinoma? The itch-scratch-lichen sclerosus hypothesis. Int J Gynecol Cancer 1999; 9: 97–9.
  • Fisher BK, Margesson LJ eds Genital skin disorders: Diagnosis and treatment. St Louis, MO: Mosby, 1998.
  • Lewis FM. Vulval lichen planus. Br J Dermatol 1998; 138: 569–75.
  • Edwards L. Desquamative vulvitis. Dermatol Clin 1992; 10: 325–37.
  • Kanwar AJ, Handa S, Ghosh S, et al. Lichen planus of childhood: a report in 17 patients. Paediatr Dermatol 1991; 8: 288–91.
  • Bain L, Geronemus R. The association of lichen planus of the penis with cell carcinoma in situ and with verrucous squamous carcinoma. J Dermatol Surg Oncol 1989; 15: 413.
  • Ferrandiz C, Ribera M. Zoon's balanitis treated by circumcision. J Dermatol Surg Oncol 1984; 10: 622–5.
  • Jolly BB, Krishnamurthy S, Vaidyanthan S. Zoon's balanitis. Urol Int 1993; 50: 182–4.
  • Kumar B, Sharma R, Rajagopalan M, Radotra BD. Plasma cell balanitis: clinical and histpathological features-response to circumcision. Genitourin Med 1995; 71: 32–4.
  • Bargman H. Pseudoepitheliomatous, keratotic, and micaceneous balanitis. Cutis 1985; 35: 77–9.
  • Bart RS, Kopf AW. On the dilemma of penile horns, pseudo-epitheliomatous hyperkeratotic and micaceous balanitis. J Dermatol Surg Oncol 1977; 3: 580–2.
  • Lortat-Jacob E, Civatti J. Balanite pseudoepithelioma-teuse keratosique et micacee (balanite synechiante evolution keratosique). Bull Soc Fr Derm Syph 1966; 73: 931–8.
  • Reid SI, Abell E. Pseudo-epitheliomatous keratotic and micaceous balanaitis. Arch Dermatol 1981; 117: 435–7.
  • Mann RJ, Allen BR. Keratotic and micaceous pseudo-epitheliomatous balanitis. Br J Urol 1982; 54: 431.
  • Jemkins D, Jakubowic HR. Pseudoepitheliomatous, keratotitc, micaceos balanitis: A clinical lesion with two histological subsets: Hyperplastic dystrophy and verru-cous carcinoma. J Am Acad Dermatol 1988; 18: 419–23.
  • Gray MR, Ansell ID. Pseudoepitheliomatous hyperker-atotic and micaceous balanitis: evidence for regarding it as pre-malignant. Br J Urol 1990; 66: 103–4.
  • Beijaards RC, van Dijk E, Hausmann R. Is pseudoe-pitheliomatous micaceous and keratotic balanitis sy-nonymous with verrucous carcinoma? Br J Dermatol 1987; 117: 641–6.
  • Irvine C, Anderson JR, Pye RJ. Micaneous and keratotic pseudoepitheliomatous balanatis and rapidly fatal fibrosarcoma of the penis occurring in the same patients. Br J Dermatol 1987; 116: 719–25.
  • Stern RSand Members of the Photochemotherapy Follow-up Study. Genital tumours among men with psoriasis exposed to psoralens and ultraviolet A radiation (PUVA) and ultraviolet B radiation. N Engl J Med 1990; 322: 1093–7.
  • Lever WF, Schaumberg-Lever G. Basal cell epithelio-ma. In: Histopathology of the skin. Philadelphia, PA: Lippincott Co. 1990: 22–633.
  • Murphy GF, Elder DE. Basal cell carcinoma. In: Rosai J, Sobin LH, eds. Atlas of tumor pathology: Non-melanotic tumors of the skin, 3rd series, Fascicle 1. Washington DC: Armed Forces Institute of Pathology, 1991: 47–60.
  • Kim ED, Kroft S, Dalton DP. Basal cell carcinoma of the penis: case report and review of the literature. J Urol 1994; 152: 1557–9.
  • Ladocsi LT, Siebert CF, Rickert RR, Fletcher HS. Basal cell carcinoma of the penis. Cutis 1998; 61: 25–7.
  • Goldminz D, Scott G, Klaus S. Penile basal cell car-cinoma. Report of a case and review of the literature. J Am Acad Dermatol 1989; 20: 1094–7.
  • Heymann WR, Soifer I, Burk PG. Penile premalignant fibroepithelioma of Pinkus. Cutis 1983; 31: 519–21.
  • Png JC, Tung KH, Wong YE, et al. Extramammary Paget's disease: a report of three cases and review of the literature. Ann Acad Med (Singapore) 1995; 24: 636–9.
  • Chang YT, Liu HN, Wong CK. Extramammary Paget's disease: a report of 22 cases in Chinese males. J Dermatol 1996; 23: 320–4.
  • Smith DJ, Hamdy FC, Evans JVVH, Falzon M, Chapple CR. Paget's disease of the glans penis: an unusual urological malignancy. Eur Urol 1994; 25: 316–9.
  • Mohammed KN. Extramammary Paget's disease pre-senting as condylomata lata. Int J STD AIDS 1993; 4: 242–3.
  • Chanda H. Extramammary Paget's disease: prognosis and relationship to internal malignancy. J Am Acad Dermatol 1985; 13: 1009–14.
  • Nakamura G, Shikata N, Shoji T, et al. An immuno-histochemical study of mammary and extrammammary Paget's disease. Anticancer Res 1995; 15: 467–70.
  • Goldblum JR, Hart WR. Vulvar Paget's disease; a clinicopathologic and immunohistochemical study of 19 cases. Am J Surg Pathol 1997; 21: 1178–87.
  • Schellhammer PF, Jordan GH, Robey EL, Spaulding JT. Premalignant lesions and nonsquamous malignancy of the penis and carcinoma of the scrotum. Urol Clin North Amer 1992; 19: 131–42.
  • Ronan SG, Eng AM, Briele HA, Walker MJ, Das Gupta TK. Malignant melanoma of the female genitalia. J Acad Dermatol 1990; 22: 428–35.
  • Ragnarsson Olding B Malignant melanoma of the vulva [dissertation]. Stockholm: Karolinska Institutet, 1999.
  • Lowe FC, Lattimer G, Metroka CE. Kaposi's sarcoma of the penis in patients with acquired immunodeficiency syndrome. J Urol 1989; 142: 1475–7.
  • Chang Y, Cesarman E, Pessin MS, Lee F, Culpepper J, Knowles DM, et al. Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma. Science 1994; 266: 1965–9.
  • Moore PS, Gao SJ, Dominguez G, Cesarman E, Lungu O, Knowles DM, et al. Primary characterization of a herpesvirus agent associated with Kaposi's sarcoma. J Virol 1996; 70: 549–58.
  • Lennette ET, Blackboum DJ, Levy JA. Antibodies to human herpesvirus type 8 in the general population and in Kaposi's sarcoma patients. Lancet 1996; 348: 858–61.
  • Regamey N, Tamm M, Wemli M, Witschi A, Thiel G, Cathomas G, et al. Transmission of human herpesvirus 8 infection from renal-transplant donors to recipients. N Engl J Med 1998; 339: 1358–63.
  • Begin LR, Clement PB, Kirk ME, Johty S, McCaughey WTE, Ferenczy A. Aggressive angiomyxoma of pelvic soft parts: a clinicopathologic study on nine cases. Hum Pathol 1985; 16: 621–8.
  • Tsang WYVV, Chan JKC, Lee KC, Fisher C, Fletcher CDM. Aggressive angiomyxoma: a report of four cases occurring in men. Am J Surg Pathol 1992; 16: 1059–65.
  • Fezzoni JC, Fechner RE, Wong LS, Rosai J. Aggressive angiomyxoma in males: a report of four cases. Am J Clin Pathol 1995; 104: 391–6.
  • Ockner DM, Sayadi H, Swanson PE, Ritter JH, Wick MR. Genital angiofibroblastoma. Comparison with aggressive angiomyxoma and other myxoid neoplasms of skin and soft tissue. Am J Clin Pathol 1997; 107: 36–44.
  • Corsi A, Perugia G, de Matteis A. Epitheloid sarcoma of the penis. Clinicopathologic study of a tumor with myogenic features and review of the literature con-cerning this unusual location. Pathol Res Pract 1999; 195: 441–8.
  • Laszlo S, Kalman E. Metaplastic carcinoma of the penis. J Urol 1998; 160: 2152–3.

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