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Clinical Research

Are positive surgical margins in radical prostatectomy specimens an independent prognostic marker?

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Pages 514-521 | Received 15 Oct 2007, Published online: 09 Jul 2009

References

  • Cancer Registry Norway. Cancer in Norway 2005. Cancer Registry Norway; 2006.
  • Kvåle R, Skarre E, Tønne A, Kyrdalen AE, Norstein J, Angelsen A, et al. Curative treatment of prostatic cancer in Norway in 1998 and 2001. Tidskr Nor Laegeforen 2006; 126: 912–6
  • Orvieto MA, Alsikafi NF, Shalhav AL, Laven BA, Steinberg GD, Zagaja GP, et al. Impact of surgical margin status on long-term cancer control after radical prostatectomy. BJU Int 2006; 98: 1199–203
  • Pound CR, Partin AW, Eisenberger MA, Chan DW, Pearson JD, Walsh PC. Natural history of progression after PSA elevation following radical prostatectomy. JAMA 1999; 281: 1591–7
  • Salomon L, Anastasiadis AG, Antiphon P, Levrel O, Saint F, De La Taille A, et al. Prognostic consequences of the location of positive surgical margins in organ confined prostate cancer. Urol Int 2003; 70: 291–6
  • Epstein JI, Amin M, Boccon-Gibbod L, Egevad L, Humphrey P, Mikuz Gregor, et al. Prognostic factors and reporting of prostate carcinoma in radical prostatectomy and pelvic lymphadenectomy specimens. Scand J Urol Nephrol Suppl 2005; 216: 34–63
  • Swindle P, Eastham J, Ohori M, Kattan MW, Wheeler T, Maru N, et al. Do margins matter? The prognostic significance of positive surgical margins in radical prostatectomy specimens. J Urol 2005; 174: 903–7
  • Obek C, Sadek S, Lai S, Civantos F, Rubinowicz D, Soloway MS. Positive surgical margins with radical retropubic prostatectomy: anatomic site specific pathological analysis and impact on prognosis. Urology 1999; 54: 682–8
  • Bott SRJ, Kirby RS. Avoidance and management of positive surgical margins before, during and after radical prostatectomy. Prostate Cancer Prostatic Dis 2002; 5: 252–63
  • Kupelian PA, Katcher J, Levin HS, Klein EA. Stage t1–2 prostate cancer: a multivariate analysis of factors affecting biochemical and clinical failures after radical prostatectomy. Int J Radiat Oncol Biol Phys 1997; 37: 1043–52
  • Karaiewicz PI, Eastham JA, Graefen M, Cagiannos I, Stricker PD, Klein E, et al. Prognostic impact of positive surgical margins in surgically treated prostate cancer: multi-institutional assessment of 5831 patients. Urology 2005; 66: 1245–50
  • Stamey TA, McNeal JE, Yemoto CM, Sigal BM, Johnstone IM. Biological determinants of cancer progression in men with prostate cancer. JAMA 1999; 281: 1395–400
  • Graefen M, Noldus J, Pichlmeier U, Haese A, Hammerer P, Fernandez S, et al. Early prostate specific antigen relapse after radical retropubic prostatectomy: prediction on the basis of preoperative and postoperative tumor characteristics. Eur Urol 1999; 361: 21–30
  • Blute ML, Bostwick DG, Bergstralh EJ, Slezak JM, Martin SK, Amling CL, et al. Anatomic site specific positive margins in organ confined prostate cancer and its impact on outcome after radical prostatectomy. Urology 1997; 50: 733–9
  • Watson RB, Civantos F, Soloway MS. Positive surgical margins with radical prostatectomy: detailed pathological analysis and prognosis. Urology 1996; 48: 80–90
  • Babaian RJ, Troncoso P, Bhadkamkar VA, Johnston DA. Analysis of clinicopathologic factors predicting outcome after radical prostatectomy. Cancer 2001; 91: 1414–22
  • Emerson RE, Koch MO, Jons TD, Daggy JK, Juliar BE, Cheng L. The influence of extent of surgical margin positivity on prostate specific antigen recurrence. J Clin Pathol 2005; 58: 1028–32
  • Solberg A, Viset T, Haugen OA, Mjønes J, Klepp O, Angelsen A. Histopathological outcome in 167 patients operated with radical retropubic prostatectomy. Scand J Urol Nephrol 2005; 39: 283–8
  • Sebe P, Makhoul B, Audet JF, Chopin D, Abbou CC, Salomon L. Prognostic value of the localization of positive resection margins after radical prostatectomy for intraprostatic tumours. Prog Urol 2003; 13: 425–9
  • Koppie TM, Bianco FJ, Kuriowa K, Reuter VE, Guillonneau B, Eastham JA, et al. The clinical features of anterior prostate cancers. BJU Int 2006; 98: 1167–71
  • Cheng L, Darson MF, Bergstralh EJ, Slezak J, Meyers RP, Bostwick DG. Correlation of margin status and extraprostatic extension with progression of prostate carcinoma. Cancer 1999; 86: 1775–82
  • Ohori M, Wheeler TM, Kattan MW, Goto Y, Scardino PT. Prognostic significance of positive surgical margins in radical prostatectomy specimens. J Urol 1995; 154: 1818–24
  • Marks RA, Koch MO, Lopez-Beltran A, Montironi R, Juliar BE, Cheng L. The relationship between the extent of surgical margin positivity and prostate specific antigen recurrence in radical prostatectomy specimens. Hum Pathol 2007; 38: 1207–11
  • Aus G, Bergdahl S, Lodding P, Lilja H, Hugosson J. Prostate cancer screening decreases the absolute risk of being diagnosed with advanced prostate cancer – results from a prospective, population-based randomized control trial. Eur Urol 2007; 51: 659–64
  • D'Amico AV, Whittington R, Malowicz SB, Schultz D, Tomaszewski JE, Wein A. Prostate-specific antigen failure despite pathologically organ-confined and margin-negative prostate cancer: the basis for an adjuvant therapy trial. J Clin Oncol 1997; 15: 1465–9
  • Chuang AY, Chang SJ, Horng CF, Tsou MH. Study of prostate cancer pathologic features in Chinese populations. Urology 2007; 69: 915–20
  • Vis AN, Schroeder FH, van der Kwast TH. The actual value of the surgical margin status as a predictor of disease progression in men with early prostate cancer. Eur Urol 2006; 50: 258–65

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