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Scandinavian Journal of Urology and Nephrology Volume 18, 1984 - Issue sup79: Scandinavian Symposium on the Physiology and Clinical Use of Ace Inhibitors
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Session I: Physiological Aspects on ACE Inhibitors

Competitive Inhibitor Binding Assay (IBA) of Captopril and Other Inhibitors of Angiotensin Converting Enzyme

Frej Fyhrquist Ilkka TikkanenFrom the Unit of Clinical Physiology, Minerva Institute for Medical Research, P.O. Box 819, SF-00101Helsinki 10, Finland and the IVth Department of Medicine, University of Helsinki
&
Carola Grönhagen-RiskaFrom the Unit of Clinical Physiology, Minerva Institute for Medical Research, P.O. Box 819, SF-00101Helsinki 10, Finland and the IVth Department of Medicine, University of Helsinki
Pages 13-16 | Published online: 27 Oct 2016

References

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  • Patchett A. The design of enalapril. In: Doyle A.E., Bearn AG, eds. Hypertension and the angiotensin system: Therapeutic approaches. New York, Raven Press 155–165, 1984
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  • Duncan E.M., Martin V.I.., Williams B.C., Al-Dujaili E.A.S., Edwards R.W. Development and optimisation of a radioimmunoassay for plasma captopril. Clin. Chem. Acta 295–303, 1983
  • Fyhrquist E., Tikkanen L., Grönhagen-Riska C., Hortling L., Hichens M. Inhibitor binding assay for Angiotension-Converting Enzyme. Clin. Chem. 30, 696–700 1984
  • Swanson B.N., Hichens M., Mojaverian P. Angiotensin converting enzyme activity in human serum: Relationship to enzyme inhibitor in vivo and in vitro. Res. Commun. Chem. Pathol. Pharmacol. 33: 525–36, 1981
  • Biollaz J., Schelling J.L., Jacot des Combes B., Brunner D.B., Desponds G., Brunner H.R. Enalapril maleate and a lysine analogue (MK–521) in normal volunteers; relationship between plasma drug levels and the renin angiotensin system. Brit. J. Pharmacol. 14:363–68, 1982
  • Funae Y., Komori T., Sasaki D., Yamamoto K. Inhibitor of angiotensin converting enzyme: (4R)-3-(2S)-3-mercapto-2-methylpropanoyl-4-thiazolidinecarboxylic acid (YS 980). Biochem. Pharmacol. 29: 1543–47, 1980
  • Boomsma F., de Bruyn J.H.B., Derkx F.H.M., Schalekamp M.A.D. Opposite effects of captopril on angiotensin converting enzyme "activity" and "concentration"; relation between enzyme inhibition and long-term blood pressure responses. Clin. Science 60: 491–98, 1981
  • Fyhrquist F., Grönhagen-Riska C., Hortling L., Forslund T., Tikkanen L., Klockars M. The induction of angiotensin converting enzyme by its inhibitors. Clin. Exp. Hypertension A5 (7&8): 1319–1330, 1983
  • Fyhrquist F., Grönhagen-Riska C., Hortling L., Forslund T., Tikkanen I. Regulation of angiotensin converting enzyme. J. Hypertension 1 (Suppl 1): 25–30, 1983

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