Improved Method for Optical Purity Determination of Ketazolam with Chiral Shift Reagent

References

• Szmuskovicz , J. , Chidester , C. G. , Duchamp , D. J. , MacKellar , F. A. and Slomp , G. 1971 . Synthesis and proof of structure of a novel benzodiazepine . Tetrahedron Lett. , : 3665 – 3668 .
   Google Scholar
• Rothchild , R. and LaPlanche , L. A. to be submitted. Calculations based on crystal structure data from Ref.1
   Google Scholar
• Martin , R. , Myers , C. and Rothchild , R. 1987 . 1H NMR spectral simplification with achiral and chiral lanthanide shift reagents. Ketazolam. Method for direct optical purity determinations . Spectrosc. Lett. , 20 ( 8 ) : 645 – 661 .
   Web of Science ®Google Scholar
• Kinkel , J. N. , Fraenkel , W. and Blaschke , G. 1987 . The separation of enantiomers on polymer coated chiral silica gels . Kontakte (Darmstadt) [Merck] , : 3 – 14 .
   Google Scholar
• Yamaguchi , S. 1983 . “ Nuclear magnetic resonance analysis using chiral derivatives ” . In Asymmetric Synthesis , Edited by: Morrison , J. D. vol. 1 , 125 – 152 . London, New York : Academic Press .
   Google Scholar
• Wenzel , T. J. 1987 . NMR Shift Reagents , 6 Boca Raton, FL : CRC Press, Inc. .
   Google Scholar
• Sanders , J. K. M. and Hunter , B. K. 1987 . Modern NMR Spectroscopy: a Guide for Chemists , 222 New York : Oxford Univ. Press .
   Google Scholar
• Haverhand , M. 1986 . Ph.D. Thesis 66 – 67 . Cambridge Univ. . Figs. 1–5
   Google Scholar
• McCreary , M. D. , Lewis , D. W. , Wernick , D. L. and Whitesides , G. M. 1974 . The determination of enantiomeric purity using chiral lanthanide shift reagents . J. Am. Chem. Soc. , 96 ( 4 ) : 1038 – 1054 .
   Web of Science ®Google Scholar
• Wenzel , T. J. 1986 . Lanthanide Shift Reagents in Stereochemical Analysis, Methods in Stereochemical Analysis 5 , 151 New York : VCH Publ., Inc. .
   Google Scholar
• Shapiro , B. L. and Johnston , M. D. Jr. 1972 . Lanthanideinduced shifts in proton nuclear magnetic resonance spectra. III. Lanthanide shift reagent-substrate equilibria . J. Am. Chem. Soc. , 94 ( 23 ) : 8185 – 8191 .
   Web of Science ®Google Scholar
• Fraser , R. R. 1983 . “ Nuclear magnetic resonance analysis using chiral shift reagents ” . In Asymmetric Synthesis , Edited by: Morrison , J. D. vol. 1 , 173 – 196 . London, New York : Academic Press . p. 182
   Google Scholar
• Solomon , I. 1955 . Relaxation processes in a system of two spins . Phys. Rev. , 99 : 559 – 565 .
   Web of Science ®Google Scholar
• Cockerill , A. F. , Davies , G. L. O. , Harden , R. C. and Rackham , D. M. 1973 . Lanthanide shift reagents for nuclear magnetic resonance spectroscopy . Chem Rev. , 73 ( 6 ) : 553 – 588 .
   Web of Science ®Google Scholar
• Rackham , D. M. 1980 . Lanthanide shift reagents. XV. Quantitation of D,L-amino acid enantiomers using chiral lanthanide shift reagents . Spectrosc. Lett. , 13 ( 5 ) : 321 – 327 .
   Web of Science ®Google Scholar
• Mayo , B. C. 1973 . Lanthanide shift reagents in nuclear magnetic resonance spectroscopy . Chem. Soc. Rev. , 2 : 49 – 74 .
   Web of Science ®Google Scholar
• Faller , J. W. and La Mar , G. N. 1973 . Chemical spindecoupling and lanthanide reagents . Tetrahedron Lett. , : 1381 – 1384 .
   Web of Science ®Google Scholar
• Jesson , J. P. 1973 . “ The paramagnetic shift ” . In NMR of Paramagnetic Molecules; Principles and Applications , Edited by: La Mar , G. N. , Horrocks , W. DeW. Jr. and Holm , R. H. 17 New York, London : Academic Press .
   Google Scholar
• Swift , T. J. 1973 . “ The paramagnetic linewidth ” . In NMR of Paramagnetic Molecules; Principles and Applications , Edited by: La Mar , G. N. , Horrocks , W. DeW. Jr. and Holm , R. H. 73 New York, London : Academic Press .
   Google Scholar
• Bulsing , J. M. and Sanders , J. K. M. 1981 . Spin-echo methods for resolution control of lanthanide-shifted NMR spectra . J. Chem. Soc., Chem. Commun. , 23 : 1201 – 1203 .
   Google Scholar
• Lenkinski , R. E. and Reuben , J. 1976 . Line broadenings induced by lanthanide shift reagents: concentration, frequency, and temperature effects . J. Magn. Reson. , 21 : 47 – 56 .
   Web of Science ®Google Scholar