Publication Cover
Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 38, 2008 - Issue 5
1,134
Views
25
CrossRef citations to date
0
Altmetric
Original Articles

Improved Solvent‐Free Dakin Oxidation Protocol

, , , &
Pages 784-788 | Received 05 Sep 2007, Published online: 15 Feb 2008

References

  • Dakin , H. D. , Clarke , H. T. and Taylor , E. R. 1941 . Catechol . Org. Synth. Coll. Vol. , 1 : 149 – 152 .
  • Nam , N.‐H. , Kim , Y. , You , Y.‐J. , Hong , D.‐H. , Kim , H.‐M. and Ahn , B.‐Z. 2002 . Preliminary structure–antiangiogenic activity relationships of 4‐senecioyloxymethyl‐6,7‐dimethoxycoumarin . Bioorg. Med. Chem. Lett. , 12 : 2345 – 2348 . and references cited therein
  • Godfrey , I. M. , Sargent , M. V. and Elix , J. A. 1974 . Preparation of methoxyphenols by Baeyer–Villiger oxidation of methoxybenzaldehydes . J. Chem. Soc. Perkin Trans. I , : 1353 – 1354 .
  • Matsumoto , M. , Kobayashi , H. and Hotta , Y. 1984 . Acid‐catalyzed oxidation of benzaldehydes to phenols by hydrogen peroxide . J. Org. Chem. , 49 : 4740 – 4741 .
  • Syper , L. 1989 . The Baeyer–Villiger oxidation of aromatic aldehydes and ketones with hydrogen peroxide catalyzed by selenium compounds — A convenient method for the preparation of phenols . Synthesis , : 167 – 172 .
  • McKillop , A. and Sanderson , W. R. 1995 . Sodium perborate and sodium percarbonate: cheap, safe and versatile oxidizing agents for organic synthesis . Tetrahedron , 51 : 6145 – 6166 .
  • Roy , A. , Reddy , K. R. , Mohanta , P. K. , Ila , H. and Junjappa , H. 1999 . Hydrogen peroxide/boric acid: an efficient system for oxidation of aromatic aldehydes and ketones to phenols . Synth. Commun. , 29 : 3781 – 3791 .
  • Varma , R. S. and Naicker , K. P. 1999 . The urea–hydrogen peroxide complex: solid‐state oxidative protocols for hydroxylated aldehydes and ketones (Dakin reaction), nitriles, sulfides, and nitrogen heterocycles . Org. Lett. , 1 : 189 – 191 .
  • Zambrano , J. L. and Dorta , R. 2003 . Improving the Dakin reaction by using an ionic liquid solvent . Synlett , : 1545 – 1546 .
  • Silva , E. T. 2000 . Instituto de Química, UFRJ . M.Sc. Thesis, Planejamento, síntese e avaliação farmacológica de novos candidatos a agentes antiinflamatórios não‐esteroidais de segunda geração derivados do do safrol. Rio de Janeiro
  • Barreiro , E. J. and Fraga , C. A. M. 2001 . “ Química medicinal: As bases moleculares da ação dos fármacos ” . 169 – 177 . Porto Alegre : Artmed .
  • Bezerra‐Neto , H. J. C. , Lacerda , D. I. , Miranda , A. L. P. , Alves , H. M. , Barreiro , E. J. and Fraga , C. A. M. 2006 . Design and synthesis of 3,4‐methylenedioxy‐6‐nitrophenoxyacetylhydrazone derivatives obtained from natural safrole: new lead agents with analgesic and antipyretic properties . Bioorg. Med. Chem. , 14 : 7924 – 7935 .
  • Tanaka , K. and Toda , F. 2000 . Solvent‐free organic synthesis . Chem. Rev. , 100 : 1025 – 1074 .

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.